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    ARRANGEMENT FOR CONTINUOUS DETERMINATION OF A SUBSTANCE
    93.
    发明公开
    ARRANGEMENT FOR CONTINUOUS DETERMINATION OF A SUBSTANCE 有权
    DEVICE FOR物质的连续测定

    公开(公告)号：EP1695050A1

    公开(公告)日：2006-08-30

    申请号：EP04734802.4

    申请日：2004-05-26

    Applicant: Kimberley Limited

    Inventor： ROTHMAIER, Markus ,  BUSSE-GRAWITZ, Max, Erick ,  SCHMIDIGER, Thomas

    IPC: G01J3/02

    CPC classification number: G01N21/4738 ,  G01J3/02 ,  G01J3/0216 ,  G01J3/10 ,  G01N21/645 ,  G01N21/78 ,  G01N2201/024

    Abstract: The invention relates to an arrangement for continuous determination of a substance comprising a chemically reacting sensor element (21) arranged in or adjacent to a limiting wall of a volume (22) containing the substance, where in a housing (2) of a modular device (1) optical elements to read the sensor element (21) are arranged, comprising at least one light source (35) illuminating the sensor element (21) and at least one sample detector (29) detecting the light scattered by the sensor element (21), and where a front side of the housing (2) comprises a coupling for the sensor element (21), so that the sensor element (21) may be interchangeably and modularly coupled to the front side of the housing (2). A glass body (24) is arranged adjacent to the coupling for direct contact with the sensor element (21) and separate conduits (34, 31) for the illuminating and for the scattered light are arranged rearward of the glass body (24). The modular device (1) allows for easily interchanging the modular sensor element (21) and provides an optical connection between the sensor element (21) and the detector (29) which is steady and allows for high quality measurements.

    FLUORESCENCE LIFETIME SENSOR MODULE AND METHOD OF DETERMINING A FLUORESCENCE LIFETIME USING A SENSOR MODULE
    97.
    发明公开
    FLUORESCENCE LIFETIME SENSOR MODULE AND METHOD OF DETERMINING A FLUORESCENCE LIFETIME USING A SENSOR MODULE 审中-公开
    荧光寿命传感器模块和使用传感器模块确定荧光寿命的方法

    公开(公告)号：EP3305170A1

    公开(公告)日：2018-04-11

    申请号：EP16192198.6

    申请日：2016-10-04

    Applicant: ams AG

    Inventor： Münzer, Martin

    IPC: A61B1/04 ,  G01B11/14 ,  G01S7/486 ,  G01N21/64 ,  A61B5/00

    CPC classification number: G01N21/6456 ,  A61B5/0071 ,  G01N21/6408 ,  G01N21/6458 ,  G01N2201/0221 ,  G01N2201/0222 ,  G01N2201/0228 ,  G01N2201/024 ,  G01N2201/0612

    Abstract: A sensor module and method for determining and imaging fluorescence lifetime based on the time-of-flight values are disclosed. The sensor module comprises an opaque housing (OH) having a first chamber (CH1) and a second chamber (CH2) which are separated by a non-transparent barrier (LB). Further, it comprises an optical emitter (OE) arranged in the first chamber (CH1) and configured to emit light through a first aperture (AP1). Pulsed excitation light of a specified wavelength is directed to optically excite a fluorescent probe (FP) positioned in the optical path of the excitation light. The module also comprises a detector (MD) arranged in the second chamber (CH2) and configured to detect through a second aperture (AP2) photons originating from the fluorescent probe (FP). The module further comprises: a measurement block (MB) configured to determine a temporal difference between an arrival time of one of the received photons with respect to the emission pulses; a histogram block (HIST) configured to accumulate the difference values in a histogram; a processing circuit (PRC) configured to compute time-of-flight values based on an evaluation of the histogram and then to compute a fluorescence lifetime from the time-of-flight values and generate an output signal (OS) being indicative of the fluorescence lifetime of the fluorescent probe; and a control unit (CU) configured to initiate pulsed emission of the optical emitter (OE).

    Abstract translation: 公开了基于飞行时间值确定和成像荧光寿命的传感器模块和方法。 传感器模块包括具有由非透明屏障（LB）分开的第一腔室（CH1）和第二腔室（CH2）的不透明外壳（OH）。 此外，它包括布置在第一腔室（CH1）中并被配置为通过第一孔径（AP1）发射光的光学发射器（OE）。 指定波长的脉冲激发光被引导以光学地激发位于激发光的光路中的荧光探针（FP）。 该模块还包括布置在第二腔室（CH2）中并被配置为通过第二孔径（AP2）检测源自荧光探针（FP）的光子的检测器（MD）。 该模块还包括：测量块（MB），其被配置为确定接收到的光子之一相对于发射脉冲的到达时间之间的时间差; 直方图块（HIST），其被配置为将所述差值累积在直方图中; 处理电路（PRC），其被配置为基于对直方图的评估来计算飞行时间值，然后从飞行时间值计算荧光寿命并且生成指示荧光的输出信号（OS） 荧光探针的寿命; 以及控制单元（CU），其被配置为启动光学发射器（OE）的脉冲发射。

    MESSVORRICHTUNG
    98.
    发明公开
    MESSVORRICHTUNG 审中-公开

    公开(公告)号：EP3058349A2

    公开(公告)日：2016-08-24

    申请号：EP14799675.5

    申请日：2014-10-14

    Applicant: IFE Innovative Forschungs- und Entwicklungs GmbH & Co. KG

    Inventor： WILLUWEIT, Thomas ,  GRIESBACH, Ralf

    IPC: G01N21/64 ,  G01N21/25

    CPC classification number: G01N21/64 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/28 ,  G01J3/32 ,  G01J3/4406 ,  G01N21/251 ,  G01N21/645 ,  G01N2201/024 ,  G01N2201/08

    Abstract: The invention relates to a measuring device ready for analysing a luminescent sample and in particular for measuring the concentration of at least one analyte in a luminescent sample, comprising: a housing having a sample receiving chamber for receiving a sample container; a sample container for receiving the luminescent sample; a radiation receiver device for receiving radiation emitted by the luminescent sample, and an evaluation device for evaluating the radiation received by the radiation receiver device from the luminescent sample. Moreover the invention provides a measuring device comprising a base part and a measurement head interchangeably disposed on the base part, wherein the measurement head is designed for analysing a luminescent sample or as a spectrometer measurement head.

    Abstract translation: 本发明涉及一种准备用于分析发光样品并且特别用于测量发光样品中至少一种分析物的浓度的测量装置，该测量装置包括：具有用于接收样品容器的样品接收室的壳体; 用于接收发光样品的样品容器; 用于接收由发光样本发射的辐射的辐射接收器装置以及用于评估由发光样本由辐射接收器装置接收的辐射的评估装置。 此外，本发明提供了一种测量装置，其包括基座部分和可互换地设置在基座部分上的测量头，其中测量头设计用于分析发光样品或者作为分光计测量头。

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