公开(公告)号：EP3006921A1

公开(公告)日：2016-04-13

申请号：EP14806991.7

申请日：2014-06-05

Applicant: Konica Minolta, Inc.

Inventor： OOTANI, Makiko ,  TAMURA, Tsuruki ,  MURAMATSU, Shinichi

IPC: G01N21/64

CPC classification number: G01N33/54373 ,  G01N21/6428 ,  G01N21/648 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2201/061 ,  G01N2333/4712 ,  G01N2333/805 ,  G01N2800/324

Abstract: Provided is a fluorescence immunoassay sensor chip and a fluorescence immunoassay method, which are capable of measuring, at the same time, a marker requiring high sensitivity due to its low content in a sample solution and a marker not requiring high sensitivity due to its high content in a sample solution. The fluorescence immunoassay sensor chip for use in fluorescence immunoassay for detecting and measuring markers contained in a sample solution includes: a dielectric member; a metal thin film formed on part of a main surface of the dielectric member; a first sensor part formed in a predetermined position on the metal thin film; and a second sensor part directly formed in a predetermined position on the dielectric member, wherein a ligand immobilized in the first sensor part and a ligand immobilized in the second sensor part capture different types of markers.

公开(公告)号：EP2994740A1

公开(公告)日：2016-03-16

申请号：EP13889149.4

申请日：2013-07-09

Applicant: Halliburton Energy Services, Inc.

Inventor： PERKINS, David L. ,  GAO, Li ,  PELLETIER, Michael T. ,  SKINNER, Neal Gregory

IPC: G01N21/27 ,  E21B49/08

CPC classification number: G01V8/12 ,  E21B47/102 ,  E21B49/087 ,  G01J3/0205 ,  G01J3/28 ,  G01J3/457 ,  G01N21/27 ,  G01N2201/061 ,  G01N2201/12

Abstract: Technologies for providing optical analysis systems using an integrated computational element with laterally-distributed spectral filters are described. A measurement tool contains an optical element including a substrate and a plurality of spectral filters supported by the substrate and arranged at different lateral positions with respect to a path of light to be received from a sample during operation of the measurement tool. Each spectral filter is formed to transmit or reflect a different subset of wavelengths in a wavelength range. Additionally, each spectral filter has a respective area exposed to the light from the sample, such that the respective areas are related to a property of the sample. The wavelength range can include wavelengths in a range from about 0.2μm to about 25μm. Additionally, the sample can include wellbore fluids and the property of the sample is a property of the wellbore fluids.

Abstract translation: 描述了使用具有横向分布光谱滤波器的集成计算元件来提供光学分析系统的技术。 测量工具包含光学元件，所述光学元件包括基板和多个光谱滤波器，所述多个光谱滤波器由所述基板支撑并且布置在相对于在所述测量工具的操作期间从样品接收的光的路径的不同横向位置处。 每个光谱滤波器被形成为透射或反射波长范围内的不同波长子集。 另外，每个光谱过滤器具有暴露于来自样品的光的相应区域，使得各个区域与样品的性质相关。 波长范围可以包括从约0.2μm至约25μm范围内的波长。 另外，样品可以包括井筒流体，并且样品的性质是井筒流体的性质。

公开(公告)号：EP2993460A1

公开(公告)日：2016-03-09

申请号：EP14804538.8

申请日：2014-05-30

Applicant: Osaka Prefecture University Public Corporation

Inventor： IIDA, Takuya ,  TOKONAMI, Shiho

IPC: G01N21/17 ,  G01N21/3577 ,  G01N21/41

CPC classification number: G01N33/54346 ,  C12Q1/6834 ,  C12Q2563/155 ,  C12Q2565/628 ,  G01N21/21 ,  G01N21/554 ,  G01N21/658 ,  G01N33/5308 ,  G01N33/553 ,  G01N2201/061 ,  G01N2201/0683

Abstract: A detection device (100) detects an analyte that may be contained in a specimen. The detection device (100) includes a plurality of gold nanoparticles, an optical trapping light source (101), an illumination light source (102), an objective lens (103), an image pick-up device (108), and a computation unit (106). The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source (101) emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens (103) focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device (108) receives light from the liquid. The computation unit (106) detects an analyte based on a signal received from the image pick-up device (108).

Abstract translation: 检测装置（100）检测可能包含在样本中的分析物。 检测装置（100）包括多个金纳米颗粒，光学捕获光源（101），照明光源（102），物镜（103），图像拾取装置（108）和计算 单元（106）。 多个金纳米颗粒各自用探针DNA修饰，使得分析物特异性地粘附于其上。 光捕获光源（101）发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜（103）将偏振光聚焦并引入含有样品和多个金纳米颗粒的液体中。 摄像装置（108）从液体接收光。 计算单元（106）基于从图像拾取装置（108）接收的信号检测分析物。

公开(公告)号：EP2888392A4

公开(公告)日：2016-03-09

申请号：EP13831127

申请日：2013-08-22

Applicant: UNIV CALIFORNIA

Inventor： BAXTER BRIAN CULLEN ,  DERISI JOSEPH L ,  FORDYCE POLLY M ,  GERVER RACHEL E ,  GÓMEZ-SJÖBERG RAFAEL ,  HELMS BRETT A ,  THORN KURT S ,  ZUCKERMANN RONALD N

IPC: C40B70/00 ,  B29B9/08 ,  C08F2/44 ,  G01N33/58

CPC classification number: G01N21/64 ,  B01F3/0807 ,  B01F3/0861 ,  B01F5/061 ,  B01F13/0059 ,  B01F13/0062 ,  B01F13/1027 ,  B01F2005/0623 ,  B01F2005/0636 ,  B82Y30/00 ,  C08F2/44 ,  C08F222/385 ,  G01N33/585 ,  G01N33/587 ,  G01N2201/061 ,  G01N2458/40

公开(公告)号：EP2990804A1

公开(公告)日：2016-03-02

申请号：EP15182922.3

申请日：2015-08-28

Applicant: SYSMEX CORPORATION

Inventor： Yamakawa, Nobuyoshi ,  Tatsutani, Hiroo ,  Ohmae, Yuichiro

IPC: G01N35/00 ,  G01N35/02

CPC classification number: G01N35/00732 ,  G01N21/78 ,  G01N35/00 ,  G01N35/00871 ,  G01N35/02 ,  G01N35/026 ,  G01N35/04 ,  G01N2021/7759 ,  G01N2035/00326 ,  G01N2035/00831 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0465 ,  G01N2035/0491 ,  G01N2201/025 ,  G01N2201/061

Abstract: [Object]
Provided is a test system operable with a simplified structure.
[Solution]
A test system (10) includes a test device (20) and a test device (30) each of which transports and tests a sample. The test device (20) includes a master control unit (25) which performs assignment of samples to the test device (20) and the test device (30), and control of a transport operation of the sample assigned to the test device (20). The test device (30) includes a slave control unit (35) which controls a transport operation of the sample assigned to the test device (30) by the master control unit (25).

Abstract translation: 提供了一种以简化的结构可操作的测试系统。 [解决方案]一种测试系统（10）包括测试装置（20）和测试装置（30），每个测试装置运送和测试样品。 测试装置（20）包括执行对测试装置（20）和测试装置（30）的样本分配的主控制单元（25），以及分配给测试装置（20）的样本的传送操作的控制 ）。 测试装置（30）包括从控制单元（35），其通过主控单元（25）控制分配给测试设备（30）的样本的传送操作。

公开(公告)号：EP2857845A4

公开(公告)日：2016-02-10

申请号：EP13800133

申请日：2013-05-24

Applicant: HITACHI HIGH TECH CORP

Inventor： YOSHIKAWA KEIKO ,  MAKINO AKIHISA

IPC: G01N35/00 ,  G01N21/01 ,  G01N21/49 ,  G01N21/82 ,  G01N35/04

CPC classification number: G01N35/025 ,  G01N21/253 ,  G01N21/49 ,  G01N21/51 ,  G01N21/82 ,  G01N33/86 ,  G01N35/0099 ,  G01N35/02 ,  G01N2015/0693 ,  G01N2021/157 ,  G01N2021/825 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2201/0256 ,  G01N2201/04 ,  G01N2201/0415 ,  G01N2201/061 ,  G01N2201/12723

Abstract: A configuration of detecting light from the front face of a light source is the best for confirming the variation of a light quantity, but when a plurality of light sources are present, as many detectors for checking a light quantity as the light sources are necessary and the apparatus configuration becomes complex. In the present invention, a detector 130 for checking a light source light quantity is installed in a reaction container transfer mechanism 117 used commonly for a plurality of detection sections, and the light quantities of light sources 124 are checked with the detector 130.

公开(公告)号：EP2980562A1

公开(公告)日：2016-02-03

申请号：EP13879924.2

申请日：2013-12-18

Applicant: Hamamatsu Photonics K.K.

Inventor： HIRAWAKE Kazumasa ,  MIWA Mitsuharu

IPC: G01N21/64

CPC classification number: G01N21/6456 ,  A61B1/00006 ,  A61B1/00009 ,  A61B1/043 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0071 ,  G01N21/6486 ,  G01N2201/061 ,  G01N2201/062

Abstract: A fluorescence viewing device 1A is configured to take a difference between one of an image of a first frame and an image of a second frame output from an imaging device 12 and the other of the first frame image and the second frame image stored in an image storage means, whereby clear observed images can be obtained without influence of background light. In the fluorescence viewing device 1A, an exposure time of a fluorescence image acquisition period and an exposure time of a background image acquisition period are different from each other. When the exposure time of the fluorescence image acquisition period and the exposure time of the background image acquisition period are made asymmetric in this manner, the observed images are acquired with good smoothness. Since ON/OFF durations of excitation light also become asymmetric according to the asymmetry of the exposure times, the device can reduce user's feeling of strangeness due to blinking of the excitation light.

Abstract translation: 荧光观察装置1A被配置为对从成像装置12输出的第一帧的图像和第二帧的图像中的一个和存储在图像中的第一帧图像和第二帧图像中的另一个 存储装置，由此可以获得清晰的观察图像而不受背景光的影响。 荧光观察装置1A中，荧光图像取得期间的曝光时间与背景图像取得期间的曝光时间互不相同。 当以这种方式使荧光图像获取时段的曝光时间和背景图像获取时段的曝光时间不对称时，以良好的平滑度获取观察图像。 由于激发光的ON / OFF持续时间也根据曝光时间的不对称性而变得不对称，所以该装置可以减少由于激发光的闪烁而导致的用户的不适感。

公开(公告)号：EP2976605A1

公开(公告)日：2016-01-27

申请号：EP14779143.8

申请日：2014-03-20

Applicant: Viavi Solutions Inc.

Inventor： O'BRIEN, Nada, A. ,  HULSE, Charles, A. ,  SIESLER, Heinz, W. ,  HSIUNG, Changmeng

IPC: G01J3/00

CPC classification number: G01N21/359 ,  G01J3/0216 ,  G01J3/26 ,  G01J3/2803 ,  G01J2003/1234 ,  G01J2003/2873 ,  G01N21/27 ,  G01N21/3563 ,  G01N21/55 ,  G01N33/12 ,  G01N2201/0221 ,  G01N2201/061 ,  G01N2201/12

Abstract: A method and apparatus for field spectroscopic characterization of seafood is disclosed. A portable NIR spectrometer is connected to an analyzer configured for performing a multivariate analysis of reflection spectra to determine qualitatively the true identities or quantitatively the freshness of seafood samples. The present invention relates to materials characterization and identification, and in particular to spectroscopic characterization of seafood.

公开(公告)号：EP2951560A4

公开(公告)日：2015-12-09

申请号：EP13873629

申请日：2013-01-29

Applicant: HEWLETT PACKARD DEVELOPMENT CO

Inventor： YAMAKAWA MINEO ,  LI ZHIYONG

IPC: G01N21/25 ,  G01N21/65

CPC classification number: A61B5/1459 ,  A61B5/6848 ,  A61B2562/0238 ,  A61B2562/12 ,  G01N21/658 ,  G01N2021/258 ,  G01N2201/061 ,  G01N2201/068

Abstract: According to an example, an apparatus for performing spectroscopy includes an elongated substrate having a shape and size to be inserted into a specimen, wherein the elongated substrate has a first end and a second end. The apparatus also includes a plurality of surface-enhanced spectroscopy (SES) elements positioned on an exterior surface of the elongated substrate at a location between the first end and the second end of the elongated substrate.

Abstract translation: 根据一个实例，用于执行光谱学的装置包括具有插入到样本中的形状和尺寸的细长衬底，其中所述细长衬底具有第一端和第二端。 该设备还包括多个表面增强光谱（SES）元件，该多个表面增强光谱（SES）元件位于细长基底的第一端和第二端之间的位置处，位于细长基底的外表面上。

公开(公告)号：EP2943776A1

公开(公告)日：2015-11-18

申请号：EP14700571.4

申请日：2014-01-09

Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

Inventor： HELL, Stefan W.

IPC: G01N21/64

CPC classification number: G01N21/64 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2201/061

Abstract: In a method for the spatially high-resolved imaging of a structure (2) of a sample (3) that has a luminophore (1), the sample (3) is subjected to luminescence excitation light (7) in a measurement range (5), which luminescence excitation light(7) excites the luminophore (1) from an excitable electronic basic state into an excited luminescent state. The sample (3) is subjected to a intensity distribution of luminescence damping light (8) in the measurement range (5), the intensity distribution having a local minimum (9), and the luminescence damping light returning the luminophore (1) from the excited luminescent state into the excitable electronic basic state. Luminescence light (10) emitted from the measurement range (5) is recorded and is assigned to the position of the local minimum (9) in the sample (3). Prior to being subjected to the luminescent excitation light (7), the sample (3) is subjected to an intensity distribution of excitation prevention light (4) in the measurement range (5), which excitation prevention light transfers the luminophore (1) from the excitable electronic basic state into a protected state, in which the luminophore (1) is protected against electronic excitations from the luminescence excitation light (7) and the luminescence damping light (8). The intensity distribution of the excitation prevention light (4) has a local minimum (6), which overlaps with the local minimum (9) of the intensity distribution of the luminescence damping light (8).