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185 条记录 (耗时 0.022 秒)

    Chromogenic compounds
    101.
    发明公开
    Chromogenic compounds 失效
    染色体化合物

    公开(公告)号：EP0124377A3

    公开(公告)日：1985-08-14

    申请号：EP84302885

    申请日：1984-04-30

    申请人： YAMAMOTO KAGAKU GOSEI CO., LTD.

    发明人： Ikegami, Seishi ,  Amako, Takamichi

    IPC分类号： C07D307/94 ,  C07D491/107 ,  B41M05/12 ,  B41M05/26 ,  C07D307/00 ,  C07D221/00 ,  C07D241/00

    CPC分类号： B41M5/145 ,  B41M5/327 ,  C07D307/94 ,  C07D491/10

    摘要： Chromogenic fluorene-9-spiro-lactones have the formula:
    where R 1 , R 2 , R 3 , R 4 and E have defined meaning. The compounds can be made by diazotizing and then effecting a ring closing reaction on the corresponding precursor primary amino-substituted phthalide, furopyridine or furopyrazine. Compounds where E is a group of the formula
    and R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are each C 1 -C 4 alkyl groups are preferred. The compounds are chromogenic and can be used in pressure and/or heat sensitive record material. They give lightfast blue to green colours when reacted with electron accepting co-reactants. The coloured forms exhibit marked absorption in the near infrared making them particularly useful in OCR detection systems.

    Pentacyclic compounds
    103.
    发明公开
    Pentacyclic compounds 失效
    PENTACYCLIC化合物

    公开(公告)号：EP0088575A3

    公开(公告)日：1984-07-11

    申请号：EP83301071

    申请日：1983-02-28

    申请人： BEECHAM GROUP PLC

    发明人： Gaster, Laramie Mary ,  Orlek, Barry Sidney

    IPC分类号： C07D487/06 ,  C07D487/04 ,  C07D223/32 ,  C07D241/38 ,  C07C93/14 ,  A61K31/555 ,  C07D241/00 ,  C07D223/00

    CPC分类号： C07D241/38 ,  C07D223/14 ,  C07D223/32 ,  C07D487/06

    摘要： Compounds of formula (I),
    or an N-oxide or pharmaceutically acceptable salt thereof, wherein R 1 is hydrogen, C 1-7 alkyl, C 3-7 cycloalkyl, C 4-7 cycloalkenyl or C 1-4 alkyl substituted by C 2 - 7 alkenyl, C 2-7 alkynyl, C 3-7 cycloalkyl, hydroxy, thiol, C 1-4 alkoxy, C 1-4 alkylthio, carboxy, C 1-4 alkoxycarbonyl, C 1-4 alkanonyl, amino optionally sustituted by one or two C 1-4 alkyl or by C 4-6 polymethylene optionally containing an oxygen or nitrogen atom, aminocarbonyl optionally N-substitued by one or two C 1-4 alkyl, or benzol or phenyl either being optionally ring-substituted by C 1-4 alkyl, C 1-4 alkoxy, halogen or trifluoromethyl, R 2 and R 3 are the same or different and are hydrogen, hydroxy, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylthio, halogen or trifluoromethyl, m is 1 to 3 and n is 1 or 2, the hydrogen atom bonded to the C a carbon atom being trans to the hydrogen atom bonded to the C b carbon atom, having mood-modifying activity such as anti-depressant activity.

    Triazaloquinoxalin-1,4-diones
    104.
    发明公开
    Triazaloquinoxalin-1,4-diones 失效
    Triazaloquinoxalin -1,4-二酮

    公开(公告)号：EP0039920A3

    公开(公告)日：1982-01-27

    申请号：EP81103498

    申请日：1981-05-07

    申请人： USV PHARMACEUTICAL CORPORATION

    发明人： Brown, Richard E. ,  Georgiev, Vasil St. ,  Kropp, Philip ,  Loev, Bernard

    IPC分类号： C07D487/04 ,  C07D471/14 ,  C07D495/14 ,  C07D491/14 ,  C07D241/44 ,  A61K31/495 ,  C07D471/04 ,  C07D249/00 ,  C07D241/00 ,  C07D221/00 ,  C07D333/00 ,  C07D307/00

    CPC分类号： C07D471/04 ,  C07D241/44 ,  C07D471/14 ,  C07D487/04

    摘要： Anti-allergic compounds of the formulae
    wherein,
    X is S or O; R 1 and R 2 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl, sulfonamido, halogen, alkoxy, alkenyloxy, alkynyloxy, cyano, hydroxy, acyloxy, nitro, amino, alkylamino, alkanoylamino, carbalkoxyamino, methanesulfonyl, carboxy, carbalkoxy, trihalomethyl, or taken together, methylenedioxy; R 3 and R 4 is hydrogen, alkyl, alkenyl, alkynyl, aryl, acyl, aralkyl, cycloalkyl, cycloalkyl CH 2 -, or carbalkoxy; and Z forms a heterocyclic ring with the two carbon atoms to which it is attached;and intermediates for their preparation.

    摘要翻译： 下式的抗过敏化合物其中X是S或O; 烷基，链烯基，炔基，环烷基，芳基，芳烷基，亚磺酰氨基，卤素，烷氧基，烯氧基，炔氧基，氰基，羟基，酰氧基，硝基，氨基，烷基氨基，烷酰基氨基， 三卤代甲基，或者合在一起，亚甲二氧基; R3和R4是氢，烷基，链烯基，炔基，芳基，酰基，芳烷基，环烷基，环烷基CH2-或烷氧羰基; Z与其所连接的两个碳原子形成杂环;以及用于其制备的中间体。