利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

34 条记录 (耗时 0.02 秒)

    PLASMA PROCESS AND REACTOR FOR THE THERMOCHEMICAL TREATMENT OF THE SURFACE OF METALLIC PIECES
    13.
    发明公开
    PLASMA PROCESS AND REACTOR FOR THE THERMOCHEMICAL TREATMENT OF THE SURFACE OF METALLIC PIECES 审中-公开
    用于金属片表面热化学处理的等离子体处理和反应器

    公开(公告)号：EP3210233A1

    公开(公告)日：2017-08-30

    申请号：EP15790820.3

    申请日：2015-10-19

    申请人： Universidade Federal De Santa Catarina (UFSC)

    发明人： BINDER, Cristiano ,  BERNARDELLI, Euclides Alexandre ,  HAMMES, Gisele ,  KLEIN, Aloisio Nelmo ,  LAMIM, Thiago De Souza ,  BINDER, Roberto

    IPC分类号： H01J37/32 ,  C23C16/448 ,  H01J37/34

    摘要： The reactor (R) has a reaction chamber (RC) provided with a support (S) for the metallic pieces (1) and with a system of an anode (2), connected to a ground (2b), and of a cathode system (3) connected to the support (S) and to a pulsating DC power supply (10). In the reaction chamber (RC), which is heated and supplied with a gas load is formed, by means of an electric discharge in the cathode (3), a gas plasma. A liquid or gas precursor is admitted in at least one tubular cracking chamber (20) associated with a high voltage energy source (30). It may be provided at least one tubular sputtering chamber (40) associated with an electric power supply (50) receiving a solid precursor. A potential difference is applied between the anode (2) and one and/or other of said tubular chambers (20, 40), in order to release the alloy elements to be ionically bombarded against the metallic pieces (1), either simultaneously or individually and in any order.

    摘要翻译： 反应器（R）具有设置有用于金属片（1）的支撑件（S）的反应室（RC）以及连接到地面（2b）的阳极（2）的系统和阴极系统 （3）连接到支架（S）和脉动直流电源（10）。 在通过阴极（3）中的放电形成被加热并供应有气体负载的反应室（RC）中的气体等离子体。 液态或气态前体进入至少一个与高压能源（30）相关的管式裂化室（20）中。 可以提供与接收固体前体的电源（50）相关联的至少一个管状溅射室（40）。 在阳极（2）和所述管状腔室（20,40）中的一个和/或另一个之间施加电位差，以便同时或单独地释放合金元素以对金属片（1）进行离子轰击 并以任何顺序。

    ACYL-HYDRAZONE AND OXADIAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF
    15.
    发明公开
    ACYL-HYDRAZONE AND OXADIAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF 审中-公开
    ACYLHYDRAZON-以及恶二唑，含药物组合物和用途

    公开(公告)号：EP2784061A1

    公开(公告)日：2014-10-01

    申请号：EP12851308.2

    申请日：2012-11-26

    申请人： Universidade Federal De Santa Catarina

    发明人： NUNES, Ricardo José ,  MASCARELLO, Alessandra ,  YUNES, Rosendo Augusto ,  STUMPF, Taisa Regina ,  LEAL, Paulo Cesar ,  YUNES, José Andres ,  PEREIRA DE SOUZA MELO, Carolina ,  CANEVAROLO, Rafael Renatino ,  DOMENEGHINI CHIARADIA, Louise ,  BORTOLINI SILVEIRA, André ,  LARANJEIRA, Anqelo Brunelli Albertoni

    IPC分类号： C07C251/86 ,  C07D271/107 ,  C07D233/54 ,  C07D333/02 ,  A61K31/166 ,  A61K31/4164 ,  A61K31/381 ,  A61P35/02

    CPC分类号： C07D333/22 ,  C07C243/38 ,  C07C251/86 ,  C07D233/64 ,  C07D271/107 ,  C07D333/36

    摘要： The present invention relates to acyl-hydrazone compounds, in particular 3,4,5-trimethoxyphenyl-hydrazide derivatives, as well as the oxadiazole analogs thereof and other similar compounds, and to the pharmaceutical use of the same for the treatment of various diseases associated with cell proliferation, such as leukemias, including acute lymphoblastic leukemia (ALL), tumours and inflammation. Acyl-hydrazones have been obtained having activity similar to that of the compound used as a standard in experiments (colchicine). The greater selectivity of the compounds according to the invention is an important feature, associated with fewer side effects than the pharmaceuticals used at present in clinical treatments. The synthetised acyl-hydrazones, more particularly the compounds 02 and 07, exhibited important anti-leukemic activity, which suggests 02 and 07 as candidates to pharmaceutical prototypes, or to pharmaceuticals for the treatment of leukemias, in particular acute lymphoblastic leukemia (ALL), tumours and other proliferative diseases, such as inflammation. The action mechanism of the most active compounds was determined by using DNA microarrays and subsequent tests indicated by the chip, besides selectivity studies in healthy human lymphocytes.

    摘要翻译： 本发明涉及酰基腙化合物，特别是3,4,5-三甲氧基苯基 - 酰肼衍生物，以及它们的恶二唑类似物和其它类似化合物，以及用于各种疾病相关的治疗药物使用相同的 与细胞增殖，：如白血病，包括急性淋巴细胞白血病（ALL），肿瘤和炎症。 酰基水螅区havebeen得到具有类似于化合物活性做了用作实验标准（秋水仙碱）。 化合物gemäß发明的更大的选择性是重要的特征，具有副作用比在临床治疗目前使用的药物较少相关联。 所述synthetised酰基水螅区，更特别地是化合物02和07表现出重要的抗白血病活性，这表明02和07作为候选药物的模板，或者以药物用于治疗白血病，特别是急性淋巴细胞白血病（ALL） 肿瘤和其它增殖性疾病，：如炎症。 该确定性通过使用DNA微阵列和由芯片所指出的，除了在健康人淋巴细胞的选择性的研究随后的试验开采的最活跃的化合物的作用机制。

    PLASMA PROCESS AND REACTOR FOR TREATING METALLIC PIECES
    16.
    发明公开
    PLASMA PROCESS AND REACTOR FOR TREATING METALLIC PIECES 有权
    等离子体处理等反应器处理的金属片

    公开(公告)号：EP2294598A1

    公开(公告)日：2011-03-16

    申请号：EP09761190.9

    申请日：2009-06-09

    申请人： Whirlpool S.A. ,  Universidade Federal De Santa Catarina (UFSC)

    发明人： BINDER, Roberto ,  KLEIN, Aloisio Nelmo ,  BINDER, Cristiano ,  HAMMES, Gisele

    IPC分类号： H01J37/32

    CPC分类号： H01J37/32522 ,  B22F2998/00 ,  H01J37/3244 ,  H01J37/32568 ,  H01J37/32623 ,  H01J37/32834 ,  H01J2237/335 ,  B22F3/11

    摘要： The plasma reactor (10) defines a reaction chamber (23) provided with a support (30) for the metallic pieces (1) and an anode-cathode system (40), and a heating means (70) is mounted externally to said plasma reactor (10). The plasma process, for a cleaning operation, comprises the steps of connecting the support (30) to the grounded anode and the cathode to a negative potential of a power source (50); feeding an ionizable gaseous charge into the reaction chamber (23) and heating the latter at vaporization temperatures of piece contaminants; applying an electrical discharge to the cathode; and providing the exhaustion of the gaseous charge and contaminants. A subsequent heat treatment comprises the steps of: inverting the energization polarity of the anode-cathode system (40); feeding a new gaseous charge to the reaction chamber (23) and maintaining it heated; applying an electrical discharge to the cathode; and exhausting the gaseous charge from the reaction chamber (23).

    COMPRESSOR COOLING SYSTEM USING HEAT EXCHANGER PRE-CONDENSER, AND COMPRESSOR PROVIDED FROM A COOLING SYSTEM
    20.
    发明公开
    COMPRESSOR COOLING SYSTEM USING HEAT EXCHANGER PRE-CONDENSER, AND COMPRESSOR PROVIDED FROM A COOLING SYSTEM 审中-公开
    有热交换器预冷凝器 - 以及与此冷却系统，配备压缩机压缩机冷却系统

    公开(公告)号：EP2678618A1

    公开(公告)日：2014-01-01

    申请号：EP12748837.7

    申请日：2012-02-16

    申请人： Whirlpool S.A.S ,  Universidade Federal De Santa Catarina - UFSC

    发明人： KREMER, Rodrigo ,  SCHREINER, João Ernesto ,  RIBEIRO, Guilherme Borges ,  DESCHAMPS, José César

    IPC分类号： F25B6/00 ,  F04C29/04 ,  F28D1/04

    CPC分类号： F04B39/06 ,  F25B31/006 ,  F25B40/04

    摘要： The present invention pertaining to the field of refrigeration equipments was designed to allow an unexpected construction and operation, and which is more efficient than the one achieved by using existing similar equipments. It is consisted of a compressor (1 ) comprised of a shell (2) within which it is located a compression cylinder (3), whereas from the shell (2) it is projected an inlet tube (5) from an evaporator and a discharge tube (6), which conducts the fluid into a condenser; at least one pre-condenser (7) associated with the compressor (1 ), the pre-condenser (7) being fed by a tubing (8) from the compression cylinder (3) located within the compressor (1 ), and equipped with an outlet tube (1 1 ); and a heat exchanger (91 ) internal to the outer region of the compressor (1 ) and cooperative with the pre-condenser (7) through the outlet tube (11 ) of the pre-condenser (7), the heat exchanger (91 ) comprising tubes attached around the shell (2) of the compressor (1 ).