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公开(公告)号：EP2814317A1
公开(公告)日：2014-12-24
申请号：EP12868550.0
申请日：2012-11-15
IPC分类号： A01N25/04
CPC分类号： A61K9/0012 , A61K9/0014 , A61K9/08 , A61K31/79 , A61K33/18 , A61K45/06 , A61K47/20 , A61K2300/00
摘要： Disclosed herein are antifungal compositions for treatment of skin and nails, as well as methods of making and using the same.
摘要翻译： 本文公开了用于治疗皮肤和指甲的抗真菌组合物，以及制备和使用它们的方法。
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公开(公告)号：EP2749301A1
公开(公告)日：2014-07-02
申请号：EP13199727.2
申请日：2013-12-27
CPC分类号： A61K9/0012 , A61L27/446 , A61L27/46 , A61L27/48 , A61L27/502 , A61L27/56 , A61L2430/02
摘要： A biocompatible, resorbable composite for osteosynthesis includes osteoconductive particles dispersed within a porous polymer matrix having a plurality of fluid passageways that expose at least a portion of a plurality of the osteoconductive particles to an exterior of the polymer matrix. The composite may further include a chemical additive incorporated within the polymer matrix, the chemical additive being configured to modify one or more of acidity, degradation rate, melting point, hydrophilicity, and hydrophobicity of the polymer matrix. A method for making the composite includes mixing the osteoconductive particles with polymer material and the chemical additive to form a mixture and treating the mixture to bind the osteoconductive particles with the polymer material to create a solid unit.
摘要翻译： 用于骨接合术的生物相容性可吸收复合材料包括分散在具有多个流体通道的多孔聚合物基质内的骨传导性颗粒，其将多个骨传导性颗粒的至少一部分暴露于聚合物基质的外部。 复合材料还可以包括结合在聚合物基体内的化学添加剂，化学添加剂被配置为改变聚合物基质的酸度，降解速率，熔点，亲水性和疏水性中的一种或多种。 制造复合材料的方法包括将骨传导性颗粒与聚合物材料和化学添加剂混合以形成混合物，并将混合物处理以将骨传导性颗粒与聚合物材料结合以产生固体单元。
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公开(公告)号：EP2491924A4
公开(公告)日：2013-04-10
申请号：EP10824907
申请日：2010-10-19
申请人： TEIKOKU SEIYAKU KK
IPC分类号： A61K31/196 , A61K9/70 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/32 , A61K47/38 , A61P29/00
CPC分类号： A61K31/196 , A61K9/0012 , A61K9/7084 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38
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公开(公告)号：EP2185143B1
公开(公告)日：2013-01-02
申请号：EP08797186.7
申请日：2008-08-05
发明人： LEE, Lih-Huei , WU, Po-Yi , SUN, Erkuan , KING, Chi-Hsin Richard
CPC分类号： A61K9/0019 , A61K9/0012 , A61K31/4709 , A61K31/4725 , A61K47/02 , A61K47/12 , A61K47/26
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15.发明公开
公开(公告)号：EP2491924A1
公开(公告)日：2012-08-29
申请号：EP10824907.9
申请日：2010-10-19
IPC分类号： A61K31/196 , A61K9/70 , A61K47/18 , A61P29/00
CPC分类号： A61K31/196 , A61K9/0012 , A61K9/7084 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38
摘要： An aqueous patch containing diclofenac sodium, wherein the patch contains a homogeneous mixed solution of diclofenac sodium, wherein the solution is obtained by mixing crotamiton, diclofenac sodium and water in the mixture ratio of crotamiton/diclofenac sodium of 8.0 or less and the mixture ratio of (water + crotamiton)/diclofenac sodium of 3.0-20.0.
摘要翻译： 含有双氯芬酸钠的水性贴剂，其中贴剂含有双氯芬酸钠的均匀混合溶液，其中，将克罗他米芬/双氯芬酸钠的混合比例为8.0以下，将克罗他米芬，双氯芬酸钠和水混合，得到溶液， （水+克罗他米通）/双氯芬酸钠3.0-20.0。
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公开(公告)号：EP2185143A2
公开(公告)日：2010-05-19
申请号：EP08797186.7
申请日：2008-08-05
发明人： LEE, Lih-Huei , WU, Po-Yi , SUN, Erkuan , KING, Chi-Hsin Richard
CPC分类号： A61K9/0019 , A61K9/0012 , A61K31/4709 , A61K31/4725 , A61K47/02 , A61K47/12 , A61K47/26
摘要： This invention relates to a parenteral formulation containing an effective amount of the compound of formula I shown in the specification and an isotonic agent. Also disclosed is a method of treating an infectious disease by administering this formulation to a subject via parenteral injection or infusion.
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公开(公告)号：EP1796632A1
公开(公告)日：2007-06-20
申请号：EP05811827.4
申请日：2005-10-11
CPC分类号： A61K9/7015 , A61K8/042 , A61K8/345 , A61K8/37 , A61K8/42 , A61K8/466 , A61K8/553 , A61K9/0012 , A61K9/0014 , A61K9/06 , A61K31/74 , A61Q19/00
摘要： A composition suitable for the local delivery of cosmetic and/or pharmaceutical agents into the skin containing at least two biocompatible organic solvents, a polar lipid, a surfactant, water, urea and a thickener wherein the organic solvents include an ester and a dihydric and/or polyhydric alcohol is provided. Also disclosed are compositions that further contain a cosmetic and/or pharmaceutical agent, along with the preparation and use thereof.
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公开(公告)号：EP1411908A1
公开(公告)日：2004-04-28
申请号：EP02747613.4
申请日：2002-08-02
申请人： ABERDEEN UNIVERSITY
发明人： BENJAMIN, Nigel
CPC分类号： A61Q3/00 , A61K8/19 , A61K9/0012 , A61K31/04 , A61K33/00 , A61K47/12 , A61K47/32 , A61K47/38
摘要： Nitrogen oxide generating compositions are useful in the treatment of subungual infections, as NO has surprisingly been found to be able to penetrate the nail to exert an anti-fungal effect.
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公开(公告)号：EP2968428B1
公开(公告)日：2018-05-30
申请号：EP14718005.3
申请日：2014-03-14
申请人： Giuliani S.p.A.
发明人： GIULIANI, Giammaria , BENEDUSI, Anna , MARZANI, Barbara , MASCOLO, Antonio , LIMITONE, Antonio , BARONI, Sergio
IPC分类号： A61K36/63 , A61K36/87 , A61K31/353 , A61K31/05 , A61K45/06 , A61Q5/00 , A61Q19/00 , A61K8/27 , A61K8/34 , A23L33/105
CPC分类号： A61K36/87 , A23L33/105 , A23V2002/00 , A61K8/19 , A61K8/23 , A61K8/27 , A61K8/345 , A61K8/4973 , A61K8/498 , A61K8/602 , A61K8/97 , A61K9/0012 , A61K9/0014 , A61K31/047 , A61K31/05 , A61K31/353 , A61K31/355 , A61K31/375 , A61K31/7048 , A61K33/04 , A61K33/30 , A61K33/34 , A61K36/06 , A61K36/63 , A61K45/06 , A61K2800/522 , A61K2800/5922 , A61K2800/92 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00 , A61Q19/08 , A61K2300/00 , A23V2200/30 , A23V2200/318 , A23V2250/21 , A23V2250/2116 , A23V2250/21168
摘要： The invention relates to a composition for pharmaceutical or nutritional or cosmetic use, formulated for oral or topical use and possessing antioxidant activity against free radicals, comprising: a) a Vitis vinifera seed, or seed and leaf, extract containing a combination of the flavonoids catechin and quercetin in a molar ratio in a range from 6:1 to 3:1, respectively, or a′) a Vitis vinifera seed, or seed and leaf, extract containing a combination of the flavonoids catechin and quercetin in a molar ratio in a range from 7:1 to 4:1, respectively, or a″) a mixture of Vitis vinifera extracts a) and a′), or a′″) a mixture of catechin and quercetin in a molar ratio in a range from 7:1 to 3:1, respectively, together with b) an olive, Olea europaea L, leaf extract having a hydroxytyrosol content in a range from 1% to 30% by weight of the extract, or b′) hydroxytyrosol in an amount equal to that contained in the b) extract.
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公开(公告)号：EP3280737A1
公开(公告)日：2018-02-14
申请号：EP16722725.5
申请日：2016-04-07
申请人： Shire Human Genetic Therapies, Inc. , The Regents of The University of Colorado, A Body Corporate
发明人： KEEFE, Dennis , ABMAN, Steven , SEEDORF, Gregory
IPC分类号： C07K16/28
CPC分类号： C07K16/2863 , A23L33/10 , A23V2002/00 , A61K9/0012 , A61K9/0019 , A61K9/0053 , A61K9/007 , A61K9/0073 , A61K31/07 , A61K31/56 , A61K33/00 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/52 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/626 , C07K2317/74 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The present invention provides, among other things, methods and compositions for treating chronic lung disorders, in particular, bronchopulmonary dysplasia (BPD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to BPD an effective amount of an anti-Flt-1 antibody, or antigen binding fragment thereof, such that at least one symptom or feature of BPD is reduced in intensity, severity, or frequency, or has delayed onset.
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