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    INTERCHANGEABLE TIP-OPEN CELL FLUOROMETER
    13.
    发明授权
    INTERCHANGEABLE TIP-OPEN CELL FLUOROMETER 有权
    荧光更换的尖端开孔的

    公开(公告)号：EP1718953B1

    公开(公告)日：2010-10-20

    申请号：EP05711948.9

    申请日：2005-01-20

    Applicant: Nalco Company

    Inventor： BANKS, Rodney, H.

    IPC: G01N21/64

    CPC classification number: G01N21/645 ,  G01N33/18 ,  G01N2021/157 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/064

    Abstract: Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.

    DETECTING AND COUNTING BACTERIA SUSPENDED IN BIOLOGICAL FLUIDS
    14.
    发明公开
    DETECTING AND COUNTING BACTERIA SUSPENDED IN BIOLOGICAL FLUIDS 审中-公开
    证据并记入生物液体悬浮细菌

    公开(公告)号：EP2238233A2

    公开(公告)日：2010-10-13

    申请号：EP08867370.2

    申请日：2008-12-24

    Applicant: Bacterioscan Ltd.

    Inventor： WEICHSELBAUM, Amnon ,  DE LA ZERDA, Jaime ,  REGEV, Issakhar

    IPC: C12M1/34

    CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

    Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

    MICROELECTRONIC SENSOR DEVICE WITH A MODULATED LIGHT SOURCE
    15.
    发明公开
    MICROELECTRONIC SENSOR DEVICE WITH A MODULATED LIGHT SOURCE 有权
    与调制光源微电子传感器装置

    公开(公告)号：EP2176644A2

    公开(公告)日：2010-04-21

    申请号：EP08789335.0

    申请日：2008-07-17

    Applicant: Koninklijke Philips Electronics N.V.

    Inventor： BRULS, Dominique, M. ,  SCHLEIPEN, Johannes, J., H., B.

    IPC: G01N21/55 ,  G01N33/543 ,  G01N21/64

    CPC classification number: G01N21/552 ,  G01N21/648 ,  G01N27/745 ,  G01N2201/064 ,  G01N2201/0691 ,  G01N2201/0696

    Abstract: The invention relates to a microelectronic sensor device and a method for making optical examinations at a carrier (11), e.g. for the detection of magnetic particles (1) at a contact surface (12) of the carrier (11) by frustrated total internal reflection (FTIR). A light source (21), particularly a laser light source, with a laser modulator (22) are used for emitting an input light beam (L1) into the carrier (11) which is modulated such that optical interferences with reflections (L1') of the input light beam (L1) from the entrance window (14) or other components of the carrier (11) are reduced/minimized. This can for example be achieved by a pulsed on/off modulation in which the first relaxation minimum of a currently emitted pulse (PN) coincides in the light source (21) with the first relaxation maximum of a reflected pulse (PN-1'). By reducing the effect of interferences, the setup is less prone to disturbances from dimensional variations that are e.g. induced by thermal extension.

    Fluorescence detecting apparatus, and fluorescence detecting method
    17.
    发明公开
    Fluorescence detecting apparatus, and fluorescence detecting method 审中-公开
    荧光素酶和荧光素酶

    公开(公告)号：EP2081016A2

    公开(公告)日：2009-07-22

    申请号：EP09000507.5

    申请日：2009-01-15

    Applicant: KONICA MINOLTA SENSING, INC.

    Inventor： Yamada, Masayuki

    IPC: G01N21/64

    CPC classification number: G01N21/474 ,  G01N21/01 ,  G01N21/6456 ,  G01N2021/6484 ,  G01N2201/064

    Abstract: A fluorescence detecting apparatus (100) includes: an excitation light emitter (1) for emitting excitation light exciting a fluorescent material onto a measurement object; an illumination light emitter (2) for emitting illumination light onto the measurement object (20); an image pickup device (50) for sensing light from the measurement object (20); and a controller (8) for controlling the image pickup device (50), the excitation light emitter (1), and the illumination light emitter (2). The excitation light is emitted from the excitation light emitter (1) onto the measurement object (20) to define an image pickup condition of the image pickup device (50), based on an image pickup result to be obtained by sensing light from the measurement object (20) by the image pickup device (50). A light amount of the illumination light to be emitted from the illumination light emitter (2) is set depending on the image pickup condition. The excitation light, and the illumination light of the set light amount are simultaneously emitted from the excitation light emitter (1) and the illumination light emitter (2), to cause the image pickup device (50) to sense light from the measurement object (20).

    Abstract translation: 荧光检测装置（100）包括：激发光发射器（1），用于将激发荧光材料的激发光发射到测量对象上; 用于将照明光发射到测量对象（20）上的照明光发射器（2）; 用于感测来自测量对象（20）的光的图像拾取装置（50）; 以及用于控制图像拾取装置（50），激发光发射器（1）和照明光发射器（2）的控制器（8）。 激发光从激发光发射器（1）发射到测量对象（20）上，以基于通过感测来自测量的光获得的图像拾取结果来定义图像拾取装置（50）的图像拾取条件 物体（20）通过图像拾取装置（50）。 从照明光发射器（2）发射的照明光的光量根据摄像条件而设定。 激发光和设定光量的照明光同时从激发光发射器（1）和照明光发射器（2）发射，以使摄像装置（50）感测来自测量对象的光（ 20）。

    Scannende Anordnung, vorzugsweise zur Erfassung von Fluoreszenzlicht
    20.
    发明公开
    Scannende Anordnung, vorzugsweise zur Erfassung von Fluoreszenzlicht 有权
    Optische Anordnung zurUnterdrückungvon Falschlicht

    公开(公告)号：EP1353209A2

    公开(公告)日：2003-10-15

    申请号：EP03013895.2

    申请日：2000-05-18

    Applicant: CARL ZEISS JENA GmbH

    Inventor： Schmidt, Stefan

    IPC: G02B21/00 ,  G02B21/16

    CPC classification number: G01N21/6456 ,  G01N21/6458 ,  G01N2201/064 ,  G01Q60/20 ,  G02B21/16

    Abstract: Optische Anordnung zur Unterdrückung von Falschlicht, das von einer beleuchteten Probe stammt, wobei die Beleuchtung der Probe und die Detektion des von der Probe emittierten Lichtes über ein Objektiv erfolgen und zur Erzeugung eines Schattenbereiches für Falschlicht in der Bildebene eine Ausblendung oder Ausspiegelung in einem Teil des Strahlengangs in Richtung der Detektion erfolgt, indem in Richtung des von der Probe emittierten Lichtes in oder in der Nähe der Pupillenebene des Objektives eine Blendenanordnung vorgesehen ist.

    Abstract translation: 在玻璃基板（2）上检测并测量薄的100nm厚的层（1a）的彩色标记分子的荧光，以通过依赖于该层中的侧向点来定量检测荧光效率。 为了对该层进行着色，将其放置在填充有水溶液的通道（3）的内侧。 衬底和通道后壁（4）形成通道。 刺激光的背反射和背散射影响透镜（5）的干涉。

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