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公开(公告)号：EP3048098B1
公开(公告)日：2018-08-15
申请号：EP16156059.4
申请日：2004-11-12
申请人： AbbVie Bahamas Ltd.
发明人： BRUNCKO, Milan , DING, Hong , ELMORE, Steven , KUNZER, Aaron R. , LYNCH, Christopher L. , MCCLELLAN, William , PARK, Cheol-Min , PETROS, Andrew , SONG, Xiaohong , WANG, Xilu , TU, Noah , WENDT, Michael D.
IPC分类号： C07D213/75 , C07D233/06 , C07D335/02 , C07D233/84 , C07D401/12 , C07D403/04 , C07D239/06 , C07D409/12 , C07C323/25 , C07D487/04 , C07D487/08 , C04B35/632 , C07D263/58 , C07D205/04 , C07D207/16
CPC分类号： C07D277/74 , C04B35/632 , C07C323/25 , C07C2601/16 , C07D205/04 , C07D207/16 , C07D211/46 , C07D211/60 , C07D211/74 , C07D213/70 , C07D213/75 , C07D233/06 , C07D233/84 , C07D239/06 , C07D263/58 , C07D277/36 , C07D295/13 , C07D295/192 , C07D307/64 , C07D335/02 , C07D401/12 , C07D403/04 , C07D409/12 , C07D487/04 , C07D487/08
摘要： Disclosed are N-acylsulfonamide compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression of one or more than one anti-apoptotic protein family member.
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公开(公告)号：EP2579854B2
公开(公告)日：2018-07-04
申请号：EP11727080.1
申请日：2011-06-09
申请人： AbbVie Bahamas Ltd.
发明人： LIEPOLD, Bernd , JUNG, Tina , HOLIG, Peter , SCHROEDER, Rudolf , SEVER, Nancy E. , LAFOUNTAINE, Justin , SINCLAIR, Brent D. , GAO, Yi , WU, Jianwei , ERICKSON, Bryan K. , KULLMANN, Simon , WESTEDT, Ulrich , PAULI, Mirko , HEITERMANN, Tanja , KOENIG, Renato , THIEL, Madlen , WOEHRLE, Gerd
IPC分类号： A61K9/14 , A61K9/16 , A61K9/20 , A61K31/4025
CPC分类号： A61K31/4025 , A61K9/146 , A61K9/1617 , A61K9/1635 , A61K9/1694 , A61K9/2027 , A61K9/2054 , A61K31/00
摘要： The present invention features solid compositions comprising Compound I A , I B , I C or I D , or a pharmaceutically acceptable salt thereof, in an amorphous form. Such compositions are useful for treating HCV infection. In one embodiment, Compound I A , I B , I C or I D , or a pharmaceutically acceptable salt thereof, is formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.
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公开(公告)号：EP2619205B1
公开(公告)日：2017-05-17
申请号：EP11764428.6
申请日：2011-09-21
申请人： AbbVie Bahamas Ltd.
IPC分类号： C07D471/08 , A61K31/439 , A61P25/00 , A61P25/28
CPC分类号： C07D451/14 , A61K31/439 , A61K45/06 , C07D471/08
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公开(公告)号：EP3056486A3
公开(公告)日：2016-09-14
申请号：EP16158981.7
申请日：2011-07-15
申请人： AbbVie Bahamas Ltd.
发明人： SHEKHAR, Shashank , FRANCZYK, Thaddeus S. , BARNES, David M. , DUNN, Travis B. , HAIGHT, Anthony R. , CHAN, Vincent S.
IPC分类号： C07D239/54 , A61K31/522 , A61P31/14 , B01J31/24 , A61K31/7056 , A61K31/513 , A61K45/06 , A61K38/21
CPC分类号： C07D239/54 , A61K31/513 , A61K31/7056 , A61K38/21 , A61K45/06 , B01J31/2423 , B01J2231/344 , B01J2231/4227 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2531/824 , A61K2300/00
摘要： This disclosure is directed to: (a) processes for preparing intermediates useful for the preparation of a compound and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b) intermediates useful for the preparation of the compound and salts; and (c) pharmaceutical compositions comprising the intermediates or salts.
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25.发明授权Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists 有权Arylschwefelpyrazolin甲脒衍生物作为5-HT 6拮抗剂
公开(公告)号：EP2610247B1
公开(公告)日：2016-05-25
申请号：EP13161112.1
申请日：2009-03-17
申请人： AbbVie Bahamas Ltd.
发明人： van Loevezijn, Arnold , Iwema Bakker, Wouter I. , Stoit, Axel , Rensink, Agatha A.M. , Venhorst, Jennifer , van der Neut, Martina A.W. , de Haan, Martin , Kruse, Cornelis G.
IPC分类号： C07D231/06 , C07D231/54 , C07D403/12 , C07D491/10 , A61K31/4155 , A61K31/416 , A61K31/4162 , A61P25/00
CPC分类号： C07D231/06 , A61K31/415 , A61K31/4155 , A61K31/4162 , A61K31/435 , A61K31/635 , A61K45/06 , C07D231/00 , C07D231/54 , C07D403/12 , C07D471/10 , C07D491/10 , C07D491/107
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26.发明授权
公开(公告)号：EP2435432B1
公开(公告)日：2015-06-24
申请号：EP10721246.6
申请日：2010-05-26
申请人： AbbVie Bahamas Ltd.
发明人： BRUNCKO, Milan , DING, Hong , DOHERTY, George , ELMORE, Steven , HASVOLD, Lisa , HEXAMER, Laura , KUNZER, Aaron R. , SONG, Xiaohong , SOUERS, Andrew J. , SULLIVAN, Gerard , TAO, Zhi-Fu , WANG, Gary T. , WANG, Le , WANG, Xilu , WENDT, Michael , MANTEI, Robert , HANSEN, Todd M.
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D491/052 , C07D519/00
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27.发明授权
公开(公告)号：EP2049472B1
公开(公告)日：2015-01-21
申请号：EP07784511.3
申请日：2007-06-22
申请人： AbbVie Bahamas Ltd.
IPC分类号： C07D207/06 , C07D401/10 , C07D403/10 , C07D417/10 , C07D495/04 , A61K31/4025 , A61K31/4439 , A61K31/455 , A61K31/501 , A61K31/506 , A61K31/4365 , A61K31/454 , A61K31/4196 , A61K31/397 , A61K31/55 , A61P25/00
CPC分类号： C07D207/06 , C07D401/10 , C07D403/10 , C07D417/10 , C07D495/04
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28.发明授权
公开(公告)号：EP2468285B1
公开(公告)日：2014-10-15
申请号：EP12160779.0
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
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公开(公告)号：EP2579855B1
公开(公告)日：2014-09-03
申请号：EP11728451.3
申请日：2011-06-07
申请人： AbbVie Bahamas Ltd.
发明人： MILLER, Jonathan , GOKHALE, Rajeev , SCHMITT, Eric, A. , GAO, Yi , LAFOUNTAINE, Justin , DIAS, Lloyd
IPC分类号： A61K9/14 , A61K9/16 , A61K31/4743
CPC分类号： A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K9/2077 , A61K31/4743
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30.发明授权CNS active fused bicycloheterocycle substituted azabicyclic alkane derivatives 有权CNS-有效和稠合杂环基取代的双环烷烃衍生物azabicyklische
公开(公告)号：EP2431368B1
公开(公告)日：2014-08-27
申请号：EP11185419.6
申请日：2007-05-15
申请人： AbbVie Bahamas Ltd.
IPC分类号： C07D451/08 , C07D451/14 , C07D519/00 , A61K31/4375 , A61P25/00
CPC分类号： C07D451/08 , C07D451/14 , C07D519/00
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