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21.发明公开
公开(公告)号：EP0381680A1
公开(公告)日：1990-08-16
申请号：EP88907739.0
申请日：1988-09-02
申请人： BIOCOMPATIBLES LTD.
CPC分类号： A61L26/0066 , A61K9/127 , A61L15/28 , A61L15/44 , A61L26/0023 , A61L2300/406 , A61L2300/626 , C08L5/04
摘要： On peut piéger des liposomes contenant un agent pharmacologiquement actif, dans une matrice d'alginate et en faire des couches minces, des fibres, des mousses ou des caillots pour préparer des pansements de blessures.
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22.发明授权
公开(公告)号：EP0157469B1
公开(公告)日：1989-05-31
申请号：EP85300356.4
申请日：1985-01-18
申请人： BIOCOMPATIBLES LTD.
IPC分类号： C07F9/10 , C07F9/14 , C07F9/15 , C07F9/65 , C07F9/09 , C08J7/12 , A61L27/00 , A61L33/00 , C07F9/02 , C07F5/00
CPC分类号： C07F9/65844 , A61L33/0082 , C07C43/315 , C07F5/003 , C07F9/091
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公开(公告)号：EP0275293A1
公开(公告)日：1988-07-27
申请号：EP87904908.0
申请日：1987-07-28
申请人： BIOCOMPATIBLES LTD.
发明人： DURRANI, Aziz, A.
CPC分类号： C08G63/692 , A61L27/18 , Y10S528/92 , Y10S623/924 , C08L67/00
摘要： Un polyester biocompatible contenant des unités répétitives dérivées de la glycérophosphorylcholine ou de la glycérophosphoryléthanolamine et au moins un acide di ou polyfonctionnel ou un dérivé réactif de ce dernier est hémocompatible et peut être utilisé dans des articles destinés à transporter des fluides corporels et dans des prothèses.
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24.发明公开
公开(公告)号：EP1141124A1
公开(公告)日：2001-10-10
申请号：EP99954247.5
申请日：1999-11-12
申请人： Biocompatibles Ltd.
发明人： STRATFORD, Peter William,Biocompatibles Limited , COURT, Jane Louise,Biocompatibles Limited , LEWIS, Andrew Lennard,Biocompatibles Limited
IPC分类号： C08L57/04 , C08K9/12 , A61K31/785 , C08J3/075 , B01J20/28
CPC分类号： C08K9/12 , C08L57/04 , C08L57/12 , C08L2666/04
摘要： A polyion complex (PIC) is formed of an anionic soluble polymer formed from ethylenically unsaturated monomers including at least one anionic or monomer and a cationic soluble polymer formed from ethylenically unsaturated monomer including at least one cationic monomer, in which the monomers used to form at least one of the polymers comprise a zwitterionic monomer and in which the monomers used to form at least one of the polymers include non-ionic monomer, preferably C1-24 alkyl(meth)acrylate, in which the overall ratio of anionic groups to cationic groups in the PIC is in the range 1.5:1 to 1:1.5, and in which the polymers are combined in ratios to provide a PIC in which there are units derived from zwitterionic monomer in an amount in the range 1 to 70 mole % based on total monomer derived units in the PIC and there are units derived from non-ionic monomer in an amount in the range 0 to 60 mole % based on total monomer derived units in the PIC. The PIC is preferably swollen in water and is a flowable gel. The zwitterionic monomer is preferably 2-(methacyloyloxyethyl)-2'-(trimethylammoniumethyl)phosphate inner salt.
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公开(公告)号：EP0247114B1
公开(公告)日：1992-04-15
申请号：EP86906871.8
申请日：1986-11-04
申请人： BIOCOMPATIBLES LTD.
IPC分类号： C08K5/00 , C08L101/00 , A61K9/22 , A61L27/00
CPC分类号： A61K9/0024 , A61K47/32 , A61K47/34 , A61L27/502 , A61L31/141 , A61L33/0052 , C08K5/0016 , C08K5/521
摘要： Plastics materials may be plasticised using lipids as the sole plasticiser or in combination with conventional plasticisers. When appropriate lipids are used thermosetting plastics and elastomers may be rendered biocompatible or therapeutic articles and sustained release medicaments may be formed.
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公开(公告)号：EP0237542B1
公开(公告)日：1991-01-30
申请号：EP86905371.0
申请日：1986-09-17
申请人： BIOCOMPATIBLES LTD.
CPC分类号： A23K50/80 , A23K20/158 , A23K40/30 , A23P10/30 , A61K9/127 , A61K9/1652 , A61K9/1658
摘要： A microcapsule comprising a payload entrapped in liposomes, the liposomes being encapsulated in a hydrocolloid matrix, wherein the matrix comprises an alginate salt and gelatin or wherein the payload comprises a nutritional or pharmacologically active component and the liposomes comprise at least one nutritional or pharmacologically active lipid. The microcapsules or a formulation thereof may be used in medicine and to deliver part or all of the dietary requirements of animals in closed system aquaculture.
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公开(公告)号：EP0161759B1
公开(公告)日：1990-09-26
申请号：EP85302048.5
申请日：1985-03-25
申请人： BIOCOMPATIBLES LTD.
IPC分类号： A61K9/50
CPC分类号： A61K38/42 , A61K9/1273
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公开(公告)号：EP0237542A1
公开(公告)日：1987-09-23
申请号：EP86905371.0
申请日：1986-09-17
申请人： BIOCOMPATIBLES LTD.
CPC分类号： A23K50/80 , A23K20/158 , A23K40/30 , A23P10/30 , A61K9/127 , A61K9/1652 , A61K9/1658
摘要： Une microcapsule comprend une charge utile incorporée dans des liposomes, ceux-ci étant encapsulés dans une matrice hydrocolloïdale, ladite matrice comprenant un sel d'alginate et de la gélatine ou ladite charge utile comprenant un composant nutritif ou pharmacologiquement actif et les liposomes comprenant au moins un lipide nutritif ou pharmacologiquement actif. Les microcapsules ou une formulation desdites microcapsules peuvent être utilisées en médecine et dans le but de distribuer la totalité ou une partie des aliments dont les animaux ont besoin dans l'aquaculture en système fermé.
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