Infrared circular dichroism measuring apparatus and method
    21.
    发明公开
    Infrared circular dichroism measuring apparatus and method 有权
    Gerätund Verfahren zum Nachweis von Zirkulardichroismus im Infrarotbereich

    公开(公告)号:EP1376099A1

    公开(公告)日:2004-01-02

    申请号:EP03013605.5

    申请日:2003-06-16

    申请人: JASCO CORPORATION

    IPC分类号: G01N21/19 G01N21/21

    CPC分类号: G01N21/19

    摘要: The object of the invention is to provide an infrared circular dichroism measuring apparatus that improves the measuring time and the measuring accuracy.
    An infrared circular dichroism measuring apparatus 101 comprising: AC signal extractors 110-112 where an interference light beam from an IR light source 102 which has passed an interferometer 103 is converted into a clockwise and a counterclockwise circularly polarized light beams and is irradiated on a sample to extract from a detected signal of detector 107 an interferogram by each of the circularly polarized light beams; DC signal extractors 113, 112 for extracting an interferogram by the IR absorption of the sample; a calculator 114 for figuring out the circular dichroism; and a selective transmitter 120 for narrowing down the wavelength region to be measured based on an IR absorption wavelength region corresponding to a vibration mode of the structure to be measured in the sample molecule.

    摘要翻译: 本发明的目的是提供一种改善测量时间和测量精度的红外圆二色性测量装置。 一种红外圆二色性测量装置101,包括:AC信号提取器110-112,其中来自经过干涉仪103的IR光源102的干涉光束被转换为顺时针和逆时针圆偏振光束,并且是 照射到样品上以从检测器107的检测信号中提取每个圆偏振光束的干涉图; DC信号提取器113,112,用于通过样品的IR吸收来提取干涉图; 用于计算圆二色性的计算器114; 以及选择发射机120,用于基于与样品分子中要测量的结构的振动模式相对应的IR吸收波长区域来缩小待测波长区域。

    Pressure control apparatus
    25.
    发明公开
    Pressure control apparatus 失效
    压力控制装置和装置,用于通过使用其进行提取,色谱分离和分离

    公开(公告)号:EP0275933A3

    公开(公告)日:1991-01-09

    申请号:EP88100485.7

    申请日:1988-01-15

    申请人: JASCO CORPORATION

    IPC分类号: G01N30/32 G05D16/20

    摘要: A pressure control apparatus is used in an apparatus for effecting extraction, chromatographic separation, and fractionation. The pressure control apparatus is intended to reduce the amount of a fluid stagnating in a valve, and is arranged to cyclically open and close the valve, thereby controlling the level of pressure. An apparatus for effecting extraction, chromatographic separation, and fractionation is designed to perform in an on-line manner the extraction of soluble components contained in a sample as well as the separation and fractionation of the components. A chromatography is connected to a downstream side of a supercritical fluid extraction device, and the aforesaid pressure control apparatus is used as back-pressure regulators (9, 18) for the chromatography and the extraction device. An extraction fluid and an elution fluid which are used in a mobile phase may be a common fluid (Fig. 1) or separate fluids (Fig. 10). At the time of extraction, the soluble components of the sample within an extraction vessel (6) is extracted by a supercritical fluid, and is delivered to an adsorption column (14). The supercritical fluid is converted into a gas by reducing the pressure within the adsorption column and thus the solubility of the fluid is lowered so that the resultant extract is adsorbed by an adsorbent packed in this column. At the time of chromatographic separation, the pressure within the adsorption column (14) is maintained at a critical pressure or higher and thus an extract is eluted by the supercritical fluid and is delivered to a separation column (16), in which the extract is separated into individual components. Then, when the pressure within the adsorption column is reduced, the supercritical fluid is gasified and the result components are collected as fractions.

    Split stream flow cell
    26.
    发明公开
    Split stream flow cell 失效
    DurchflussküvettemitStrömungsspaltung。

    公开(公告)号:EP0294312A1

    公开(公告)日:1988-12-07

    申请号:EP88710013.9

    申请日:1988-06-06

    申请人: JASCO CORPORATION

    IPC分类号: G01N21/05

    摘要: The present invention relates to a split stream flow cell which is used for a UV detector of liquid chromatography and in which a UV light for detecting absorption of the light is transmitted through a sample solution flowing in the cell. It is an object of the present invention to reduce the influences of both the flow effect and the liquid lens effect without cell volume being made too large. To this end, a split stream flow cell of the present invention comprises a split flow channel (12) which passes through a cell block (10) and which has a central portion communicating with an inlet channel (18), both ends communicating with an outlet channel (38), and both sides symmetrical with respect to the central portion, the diameter thereof being increased from a given position in the central portion toward both ends.

    摘要翻译: 本发明涉及一种用于液相色谱的紫外检测器的分流式流动池,其中用于检测光的吸收的紫外光透射通过在该池中流动的样品溶液。 本发明的目的是减小流动效应和液体透镜效应两者对细胞体积过大的影响。 为此,本发明的分流流动池包括通过电池块(10)并且具有与入口通道(18)连通的中心部分的分流通道(12),两端与 出口通道(38),并且两侧相对于中心部分对称,其直径从中心部分中的给定位置向两端增加。

    INFRARED CIRCULAR DICHROISM MEASUREMENT DEVICE

    公开(公告)号:EP4220128A1

    公开(公告)日:2023-08-02

    申请号:EP20955307.2

    申请日:2020-09-28

    申请人: JASCO Corporation

    IPC分类号: G01N21/19

    摘要: This invention provides a circular dichroism measurement device that is capable of measuring infrared circular dichroism with a suitable signal-to-noise ratio even if a sample has two or more absorbances. This circular dichroism measurement device comprises: a laser light source (QCL) capable of sweeping the wavenumber of laser light within an infrared wavenumber range including at least one absorption peak of a sample; a sample chamber (15) within which the sample is disposed; a polarization modulation element (14) that modulates the polarization state of swept laser light having a specific wavenumber before or after the laser light passes through the sample; a detector (17) that detects intensity variation in the laser light that has passed through the sample and had the polarization state thereof modulated; and a signal processing unit (40) that extracts a direct current component (DC) and an alternating current component (AC) synchronized with the modulation frequency from a detection signal from the detector (17) and calculates an infrared circular dichroism value for the sample on the basis of the ratio (AC/DC) of the components.

    Chromatography system, signal processing apparatus, chromatography data processing apparatus, and program
    29.
    发明公开
    Chromatography system, signal processing apparatus, chromatography data processing apparatus, and program 审中-公开
    色谱系统,信号检测器,色谱分析仪

    公开(公告)号:EP2778675A1

    公开(公告)日:2014-09-17

    申请号:EP14158583.6

    申请日:2014-03-10

    申请人: Jasco Corporation

    IPC分类号: G01N30/86 G01N30/74

    摘要: A chromatography system has a multi-channel detection device 10 including a flow cell 12 to which a specimen is supplied, optics for directing light from light sources 11 to the flow cell 12 and outputting light that has passed through the flow cell, and a multi-channel detector 13 disposed on an output of the optics. The optics has a function of dispersing light in wavelength in an optical path. The detector 13 receives the light dispersed in wavelength. The multi-channel detection device 10 also has a signal processing part 14 connected to the detector. The chromatography system has a data processing apparatus 20. The signal processing circuit has a function of calculating an absorbance by absorbance = -log 10 ( I / I 0 ) using the intensity I of light having a wavelength to be measured that is outputted from the detector and a reference intensity I 0 of light that is an average of intensities of light having different wavelengths that is produced at the same point of time as the light having a wavelength to be measured.

    摘要翻译: 色谱系统具有多通道检测装置10,该多通道检测装置10包括提供试样的流动池12,用于将来自光源11的光引导到流动池12并输出已经通过流动池的光的光学器件, 通道检测器13设置在光学器件的输出端上。 光学元件具有在光路中分散波长的光的功能。 检测器13接收波长分散的光。 多通道检测装置10还具有连接到检测器的信号处理部14。 色谱系统具有数据处理装置20.信号处理电路具有使用从被测定的波长输出的具有待测波长的光的强度I计算吸光度= -log 10(I / I 0)的吸光度的功能 检测器和光的参考强度I 0,其是在与要测量的波长相同的时间点产生的具有不同波长的光的平均值的平均值。

    Spectroscopic confocal microscope with aperture stop for increased spatial resolution and parallelized data acquisition
    30.
    发明公开
    Spectroscopic confocal microscope with aperture stop for increased spatial resolution and parallelized data acquisition 审中-公开
    具有孔径光谱共焦显微镜,以增加的空间分辨率和一个并行数据采集

    公开(公告)号:EP2685304A1

    公开(公告)日:2014-01-15

    申请号:EP13175871.6

    申请日:2013-07-10

    申请人: Jasco Corporation

    IPC分类号: G02B21/00

    摘要: A confocal microscopy apparatus (10) for irradiating a measuring region of a specimen with light and for obtaining spectral information of light from the measuring region, comprising: a specimen irradiation means (20); an objective lens (32); an imaging lens (34); an aperture stop (36) having a plurality of openings disposed on an imaging plane of the imaging lens; and spectrum obtaining means (50, 60) for detecting and for obtaining the spectral information of light passing through each of the openings. Therefore, the spectral information according to light passing through each opening maintains the same spatial resolution as that obtained with the aperture stop having a circular opening, and the spectral information of light from the plurality of points of the specimen can be obtained altogether. Consequently, distribution measurement of a given measuring region of the specimen can be executed with high resolution and at high speed.

    摘要翻译: 甲共聚焦显微镜装置(10),用于用光照射的样本的测量区域和用于从所述测量区域获取的光的光谱信息,包括:检体照射装置(20); 至物镜(32); 在成像透镜(34); 在具有设置在所述成像透镜的成像平面开口的多元性孔径光阑(36); 和频谱获取装置,用于检测和用于获得光的穿过每个开口的光谱信息(50,60)。 因此,光谱信息gemäß点亮穿过每个开口保持空间分辨率就与具有圆形开口的孔径光阑获得相同的,并且光从样品的点的多个频谱信息可以完全获得。 因此,样品中的给定测量区域的分布测定能够以高分辨率和高的速度执行。