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公开(公告)号:EP3487862A1
公开(公告)日:2019-05-29
申请号:EP17746324.7
申请日:2017-07-21
发明人: CHENG, Peter T. W. , MENG, Wei , LIU, Mark , WANG, Bei , ZHAO, Rulin
IPC分类号: C07F9/40 , A61K31/675 , A61P3/00
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公开(公告)号:EP3433247A1
公开(公告)日:2019-01-30
申请号:EP17715361.6
申请日:2017-03-23
发明人: PI, Zulan , BILDER, Donna M , BRIGANCE, Robert Paul , FINLAY, Heather , JIANG, Wen , JOHNSON, James A. , LAWRENCE, R. Michael , MENG, Wei , MYERS, Michael C. , PHILLIPS, Monique , TORA, George O. , ZHANG, Xiaojun
IPC分类号: C07D401/14 , C07D401/06 , C07D403/06 , C07D403/14 , C07D239/557 , C07D417/14 , C07D471/04 , A61K31/505 , A61K31/506 , A61P35/00
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公开(公告)号:EP3114121B1
公开(公告)日:2018-09-26
申请号:EP15710687.3
申请日:2015-03-05
发明人: MENG, Wei , ZHAO, Guohua
IPC分类号: C07D401/14 , C07D401/04 , C07D409/04 , C07D409/14 , C07D417/14 , A61K31/4418 , A61K31/444 , A61K31/506 , A61P3/00 , A61P9/00
CPC分类号: C07D409/14 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/506 , A61K45/06 , C07D401/04 , C07D401/14 , C07D409/04 , C07D417/14
摘要: or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
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公开(公告)号:EP2558461B1
公开(公告)日:2015-12-02
申请号:EP11716736.1
申请日:2011-04-14
发明人: MENG, Wei , CHENG, Peter T. W.
IPC分类号: C07D403/12 , C07D417/12 , A61P3/10 , A61P3/04
CPC分类号: C07D403/12 , C07D417/12
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25.
公开(公告)号:EP1791852B1
公开(公告)日:2008-12-31
申请号:EP05814242.3
申请日:2005-09-23
发明人: WASHBURN, William , MENG, Wei
IPC分类号: C07H7/04
摘要: A compound of the formula (I) A method is also provided for treating diabetes and related diseases employing the above compound alone or in combination with another therapeutic agent.
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26.AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS 有权
标题翻译: 二肽基肽酶IV抑制剂ON AZOLOPYRIMIDINBASIS和方法公开(公告)号:EP1836206A1
公开(公告)日:2007-09-26
申请号:EP05855291.0
申请日:2005-12-23
IPC分类号: C07D487/04 , A61K31/437 , A61P3/10
CPC分类号: C07D487/04
摘要: Compounds are provided having the formula (I): Formula (I) wherein R, X, Y, A and n are as defined herein.
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公开(公告)号:EP1506211B1
公开(公告)日:2007-02-07
申请号:EP03736643.2
申请日:2003-05-15
CPC分类号: C07C43/225 , A61K31/70 , A61K31/7034 , A61K45/06 , C07C45/46 , C07C49/84 , C07H7/04 , C07H15/203 , A61K2300/00
摘要: An SGLT2 inhibiting compound is provided having the formula[Chemical structure] A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or in combination with another antidiabetic agent or other therapeutic agent.
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公开(公告)号:EP3362442B1
公开(公告)日:2020-01-29
申请号:EP16784732.6
申请日:2016-10-13
发明人: KIM, Soong-Hoon , CHAO, Hannguang J. , FINLAY, Heather , JIANG, Ji , JOHNSON, James A. , LAWRENCE, R. Michael , MYERS, Michael C. , PHILLIPS, Monique , TORA, George O. , MENG, Wei
IPC分类号: C07D401/14 , C07D405/14 , C07D413/14 , C07D213/82 , C07D401/06 , C07D401/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/10 , C07D491/107 , C07D498/10 , A61K31/4427 , A61P9/00
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公开(公告)号:EP3362442A1
公开(公告)日:2018-08-22
申请号:EP16784732.6
申请日:2016-10-13
发明人: KIM, Soong-Hoon , CHAO, Hannguang J. , FINLAY, Heather , JIANG, Ji , JOHNSON, James A. , LAWRENCE, R. Michael , MYERS, Michael C. , PHILLIPS, Monique , TORA, George O. , MENG, Wei
IPC分类号: C07D401/14 , C07D405/14 , C07D413/14 , C07D213/82 , C07D401/06 , C07D401/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/10 , C07D491/107 , C07D498/10 , A61K31/4427 , A61P9/00
摘要: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
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30.PHOSPHONATE AND PHOSPHINATE COMPOUNDS AS GLUCOKINASE ACTIVATORS 有权
标题翻译: 膦酸盐和PHOSPHINATVERBINDUNGEN ALS葡萄糖激酶激活公开(公告)号:EP2059522B1
公开(公告)日:2014-01-08
申请号:EP07812578.8
申请日:2007-07-03
发明人: RYONO, Dennis E. , CHENG, Peter T.W. , BOLTON, Scott A. , CHEN, Sean S. , SHI, Yan , MENG, Wei , TINO, Joseph A. , ZHANG, Hao , SULSKY, Richard B.
IPC分类号: C07F9/32 , C07F9/40 , A61K31/675 , A61P3/00
CPC分类号: C07F9/6539 , C07F9/582 , C07F9/587 , C07F9/65032 , C07F9/650964 , C07F9/650982 , C07F9/65181
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