公开(公告)号：EP1380337B1

公开(公告)日：2012-11-14

申请号：EP03015457.9

申请日：2003-07-09

申请人： TOSOH CORPORATION

发明人： Futami, Toru ,  Ohkawa, Tomohiro ,  Oikawa, Tomoyuki ,  Kawai, Akira ,  Katayama, Koji ,  Nishizawa, Keiichiro

IPC分类号： B01J19/00 ,  B01F13/00

CPC分类号： B01J19/0093 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01F2005/0088 ,  B01F2215/0409 ,  B01F2215/0427 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/086

公开(公告)号：EP1567269B1

公开(公告)日：2007-01-03

申请号：EP03789521.6

申请日：2003-11-27

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： SARRUT, Nicolas

IPC分类号： B01L3/00 ,  G01N27/26

CPC分类号： B01F13/0076 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00853 ,  B01J2219/00889 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2400/0415

摘要： The invention concerns a microfluidic device (1) comprising at least one micro-channel delimited by lower (2), lateral (4) and upper (5) walls and designed to contain at least one liquid (6) and at least one fluid (7) non-miscible with the liquid (6). The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The stabilizing means include at least one electrode (9) arranged on at least one part of a first wall of the micro-channel, over the entire length thereof and at least one counter-electrode (10) arranged over the entire length of the micro-channel, on at least one part of a second wall, arranged opposite the electrode. The electrode (9) and the counter-electrode (10) are preferably respectively arranged on the micro-channel lower (2) and upper (5) walls.

公开(公告)号：EP1610892A1

公开(公告)日：2006-01-04

申请号：EP04726208.4

申请日：2004-04-07

申请人： GLAXO GROUP LIMITED

发明人： HUGHES, Ian GlaxoSmithKline ,  WARRINGTON, Brian Herbert GlaxoSmithKline ,  WONG, Yuk Fan GlaxoSmithKline

IPC分类号： B01J19/00 ,  B01L3/00

CPC分类号： B01L3/5027 ,  B01F13/0059 ,  B01F13/0093 ,  B01F15/0404 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/005 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/0086 ,  B01L2200/143

摘要： A system (20) having a microfluidic channel structure (3;103) in which fluids (A, B; A-C) are able to interact to produce at least one product, and an automated closed-loop control mechanism to autonomously control a condition in, or of, the channel structure, the control mechanism having:- a sensor (27) adapted to produce a sensor signal (29) representative of a predetermined property of the at least product which is dependent on the condition in, or of, the channel structure, means (25) adapted to vary the condition in, or of, the channel structure, and a computer (21) which is adapted to receive the sensor signal and to cause the means to vary the condition in, or of, the channel structure in dependence of the sensor signal.

公开(公告)号：EP1415708A3

公开(公告)日：2004-12-29

申请号：EP03024900.7

申请日：2003-10-31

申请人： Hitachi, Ltd.

发明人： Sano, Tadashi, c/o Hitachi,Ltd. IP Group ,  Riyake, Ryo c/o Hitachi,Ltd. IP Group ,  Koide, Akira, c/o Hitachi,Ltd. IP Group ,  Harada, Takeshi, c/o Hitachi,Ltd. IP Group

IPC分类号： B01J19/00 ,  B01D11/04 ,  B01F13/00

CPC分类号： B01F13/0062 ,  B01F3/0807 ,  B01F5/0453 ,  B01F5/0682 ,  B01F13/0066 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00837 ,  B01J2219/0084 ,  B01J2219/00891 ,  B01J2219/00923 ,  B01L3/5027 ,  B01L2200/0636 ,  G01N35/08 ,  Y10T137/2224 ,  Y10T137/2564 ,  Y10T436/255

摘要： In a chemical reactor (50), a gas and a liquid which are in trace volumes are used to produce air bubbles and thus increase the interface area between the gas and liquid, substantially enhancing the efficiency of reaction between the gas and liquid. The chemical reactor comprises the following: a sheath flow forming block (10) which forms a plurality of alternating sheath flows with two mutually unmixable fluids (61, 62), a plurality of inlet ports (1, 2) through which the two fluids (61, 62) flow into the sheath flow forming block (10), a contraction zone (11) which simultaneously contracts a plurality of sheath flows formed in the sheath flow forming block (10), and reaction flow channels (21, 22) each of which is connected with the contraction zone (11) and is smaller in width than the sheath flow forming block (10).

公开(公告)号：EP1380337A2

公开(公告)日：2004-01-14

申请号：EP03015457.9

申请日：2003-07-09

申请人： Tosoh Corporation

发明人： Futami, Toru ,  Ohkawa, Tomohiro ,  Oikawa, Tomoyuki ,  Kawai, Akira ,  Katayama, Koji ,  Nishizawa, Keiichiro

IPC分类号： B01J19/00 ,  B01F13/00

CPC分类号： B01J19/0093 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01F2005/0088 ,  B01F2215/0409 ,  B01F2215/0427 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00833 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/086

摘要： A fine channel device comprising a fine channel (19) provided with at least two inlet ports (11, 28, 29) for feeding fluid, inlet channels communicated with the inlet ports, a confluent portion (37) communicated with the inlet channels to feed the fluid, a branch portion (4) communicated with the fine channel, from which at least two outlet channels are branched to feed predetermined amounts of fluid, and outlet ports (12, 30, 31) communicated with the outlet channels, wherein the fine channel (19) is provided with a plurality of partition walls (22) along a boundary formed by at least two kinds of fluid (13, 14) fed from the inlet ports so as not to cause mutual contamination of fluid, whereby different kinds of fluid flowing in the fine channel in an adjacent state can form stably the fluid boundary and each kind of fluid can be discharged from a predetermined outlet port separately without causing the mutual contamination of fluid between adjacent flows of the fluid, is provided.
By using such fine channel device, a chemical reaction can be accelerated by making two different kinds of fluid contact at the fluid boundary in a flowing direction of fluid in the fine channel of the fine channel device.

摘要翻译： 包括细通道的细通道装置（19）设置有至少两个进气口（11，28，29），用于将流体，与所述入口端口连通的入口通道，与所述入口通道连通的合流部（37）喂 流体，分支部分（4）连通的微细流路，从该至少两个出口通道被分支成进料的流体的预定量，和出口端口（12，30，31）与出口通道连通，worin细 信道（19）上设置有隔壁（22）沿一个边界由至少两种从入口口供给流体（13，14）的形成有多个，以便不使流体的相互污染，由此不同种类的 在相邻的状态下在细通道中流动在可稳定地形成所述流体边界和各种流体的流体可从预定的排出口排出单独而不引起的流体的流动相邻之间的流体的相互污染，提供了。 通过使用搜索细通道装置，化学反应可以通过在流体中的微细流路装置的微细流路的流动方向的流体边界制作两种不同类型的流体接触的加速。

公开(公告)号：EP1320741A1

公开(公告)日：2003-06-25

申请号：EP01973129.8

申请日：2001-09-18

申请人： University of Washington

发明人： KAMHOLZ, Andrew ,  MUNSON, Matthew ,  SCHILLING, Eric ,  HAWKINS, Kenneth ,  WEIGL, Bernhardt, H. ,  BARDELL, Ronald L.

IPC分类号： G01N15/06 ,  G01N21/64 ,  G01N30/00 ,  G01N35/08 ,  B01D11/00

CPC分类号： F15C1/14 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01F13/0093 ,  B01F15/0203 ,  B01F15/0233 ,  B01F2005/0031 ,  B01F2215/0431 ,  B01J19/0093 ,  B01L3/502776 ,  B01L2200/0621 ,  B01L2200/0636 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0457 ,  B01L2400/0655 ,  B01L2400/0688 ,  F16K99/0001 ,  F16K2099/0074 ,  F16K2099/0078 ,  F16K2099/008 ,  F16K2099/0084 ,  G01N21/07 ,  G01N2035/00237 ,  G01N2035/00495 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/25 ,  Y10T436/2575

摘要： Multifluidic devices and methods are provided for enhancing detection of a diffusion pattern formed by particles diffusing between at least two fluid streams (I) parallel laminar flow such that an interface is formed between them by increasing the dimension of the streams in the diffusion direct. This may be accomplished by flowing the streams through a transforming turn, or by flowing the streams through a channel having diverging walls. Devices and methods are also provided for enhancing diffusion between two streams comprising changing the interface between said streams from a narrow interface to a broad interface.

公开(公告)号：EP0790849B1

公开(公告)日：2003-03-26

申请号：EP95934715.4

申请日：1995-10-20

申请人： CENTRAL RESEARCH LABORATORIES LIMITED

发明人： HOLMES, Robert, George, Godfrey ,  BULL, Adrian, James ,  SIMPER, Adrian, Mark ,  SHAW, John, Edward, Andrew ,  BRENNAN, David, Edward ,  TURNER, Robert, Edward ,  SIMPSON, Richard, Iain ,  WESTWOOD, Lyn

IPC分类号： B01D11/04 ,  B01D61/28 ,  G01N1/40

CPC分类号： G01N1/4005 ,  B01D11/04 ,  B01D11/0403 ,  B01D11/0407 ,  B01D11/0415 ,  B01D11/0419 ,  B01D11/0426 ,  B01D11/0496 ,  B01D61/246 ,  B01D61/28 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00833 ,  B01J2219/00837 ,  B01J2219/00995 ,  G01N25/14 ,  G01N27/44743 ,  G01N30/6069 ,  G01N30/6095 ,  G01N2001/4016

摘要： In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the fluids without mixing, method and apparatus are disclosed having first and second fluid flow paths (11, 12) carrying first and second immiscible fluids, the flow paths communicating with one another in an interface region (16) in which the fluids contact one another and a stable open interface is formed. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the interface without mixing. The width of the flow paths in the interface region measured normal to the interface lies between 10 and 500 micrometres.

公开(公告)号：EP1086143A1

公开(公告)日：2001-03-28

申请号：EP99915632.6

申请日：1999-03-17

申请人： Axiva GmbH

发明人： PYSALL, Detlev ,  WACHSEN, Olaf ,  BAYER, Thomas ,  WULF, Stefan

IPC分类号： C08F2/00 ,  B01J19/24 ,  C08F2/06 ,  B01J19/00 ,  C08F20/12

CPC分类号： B01F13/0059 ,  B01F5/0403 ,  B01F2005/0031 ,  B01F2015/062 ,  B01F2215/0049 ,  B01J19/0093 ,  B01J19/242 ,  B01J2219/00889 ,  B29K2105/0002

摘要： Two reaction partners (educts) are stored in separate receptacles (2, 3, 4, 5) and are pumped at an overpressure to a micromixer (18) via warmed heat exchangers (11) using regulating and dosing devices (6, 7) such as dosing pumps. The educts are respectively separated and heated inside the heat exchangers (11, 12) in such a way that the required reaction temperature is immediatedly attained in the micromixer (18) during the mixing process. Polymerization occurs downstream in a tubular reactor (20) that is made of series-mounted tubes (21, 22, 23).