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公开(公告)号：EP3698815A1
公开(公告)日：2020-08-26
申请号：EP20170093.7
申请日：2015-03-20
发明人： BADYLAK, Stephen F. , DEARTH, Christopher Lee , KEANE, Timothy Joseph, Jr. , TURNER, Neill Jordon
摘要： Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
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公开(公告)号：EP3600358A1
公开(公告)日：2020-02-05
申请号：EP18717798.5
申请日：2018-03-26
发明人： GILBERT, Thomas Wayne , DI, Yuanpu
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公开(公告)号：EP3600160A1
公开(公告)日：2020-02-05
申请号：EP18772186.5
申请日：2018-03-16
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公开(公告)号：EP2858975B1
公开(公告)日：2019-04-24
申请号：EP13800256.3
申请日：2013-03-13
申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education , The United States Government as Represented by the Department of Veterans Affairs
IPC分类号： A61K31/137 , A61K31/341 , A61K31/381 , A61K31/402 , A61K31/4155 , A61K31/427 , A61K31/4418 , A61K31/506 , A61K31/5375 , C07D213/36 , C07D231/10 , C07D231/12 , C07D333/20 , C07D413/12 , C07D471/04 , C07D471/10 , A61P3/10 , A61P11/06 , A61P19/00 , A61P25/00 , A61P35/00
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公开(公告)号：EP3458079A1
公开(公告)日：2019-03-27
申请号：EP17799914.1
申请日：2017-05-12
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公开(公告)号：EP2608799B1
公开(公告)日：2018-12-12
申请号：EP11820530.1
申请日：2011-08-23
发明人： OKADA, Hideho
IPC分类号： A61K38/08 , A61K39/39 , A61K39/395 , A61P35/00
CPC分类号： A61K39/0011 , A61K9/0019 , A61K38/17 , A61K38/1709 , A61K38/177 , A61K38/2086 , A61K39/39 , A61K2039/5154 , A61K2039/55566 , A61K2039/55583 , A61K2039/572 , A61K2039/70 , C07K14/4703 , C07K14/4705 , C07K14/705 , C07K14/7155 , A61K2300/00
摘要： Provided herein are interleukin-13 receptor α2 peptide-based brain cancer vaccines and methods for treating and vaccinating against brain cancer comprising administering to patients in need thereof interleukin-13 receptor α2 peptide-based brain cancer vaccines. Also provided herein are regimens comprising interleukin-13 receptor α2 peptides and at least one additional peptide and/or immunostimulant.
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公开(公告)号：EP3399952A1
公开(公告)日：2018-11-14
申请号：EP17736224.1
申请日：2017-01-04
申请人： University of Pittsburgh- Of the Commonwealth System of Higher Education , The United States Government as represented by The Department of Veterans Affairs , Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： COOPER, Rory, Alan , WANG, Hongwu , DAVELER, Brandon, Joseph , GEBROSKY, Benjamin, Todd , GRINDLE, Garrett, G. , PEARLMAN, Jonathan, L. , SCHNEIDER, Urs , MINZENMAY, David
CPC分类号： A61G5/045 , A61G5/048 , A61G5/10 , A61G5/1051
摘要： A personal mobility device includes a frame, a plurality of wheels attached to the frame and one or more pneumatic motors. Each of the one or more pneumatic motors has a drive shaft in operative connection with at least one of the plurality of wheels. The personal mobility device further includes at least one tank (that is, a storage container) for storage of a pressurized gas in operative connection with the one or more pneumatic motors to supply pressurized gas to the one or more pneumatic motors and a control system in operative connection with the at least one tank and with the one or more pneumatic motors.
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公开(公告)号：EP3383471A1
公开(公告)日：2018-10-10
申请号：EP16871478.0
申请日：2016-12-01
发明人： TAI, Changfeng
CPC分类号： A61F7/12 , A61F7/007 , A61F7/02 , A61F2007/0093 , A61F2007/0096 , A61F2007/0295 , A61F2007/126 , A61M19/00 , A61M2205/3368 , A61M2205/3523 , A61M2205/3606 , A61M2205/3653 , A61M2205/3673 , A61M2205/3686
摘要： Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g. 37° C. in a human), such as from 43° C. to 54° C. for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15° C. to 30° C.
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公开(公告)号：EP3359642A1
公开(公告)日：2018-08-15
申请号：EP16854326.2
申请日：2016-10-06
摘要： Disclosed herein are various bioreactor devices and systems for growing cellular material, and related methods of growing cellular material. In some cases, a system can include a bioreactor system having one or more wells with at least one fluidic passageway coupled to each well to feed fluids to biological material being developed inside the well. In some cases, a bioreactor system can include a main body comprising the perimeter of the well and the fluidic passageways, a cover that forms the top of the well and provides optical access into the well, and a base that forms the bottom surface of the well. The cover and base can be attached and detached from the main body to seal the well closed and to physically access the contents of the well.
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