公开(公告)号：EP1290187A2

公开(公告)日：2003-03-12

申请号：EP01946479.1

申请日：2001-06-14

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LAL, Preeti ,  BANDMAN, Olga ,  BOROWSKY, Mark,L ,  AU-YOUNG, Janice ,  LU, Yan ,  GANDHI, Ammena, R ,  TRIBOULEY, Catherine, M ,  WALIA, Narinder,K ,  YAO, Monique, G ,  LU,Dyung, Aina,M ,  GREENWALD,Sara, R ,  RAMKUMAR,Jayalaxmi ,  GRIFFIN,Jennifer, A ,  KEARNEY, Liam ,  BURFORD, Neil ,  NGUYEN, Danniel, B ,  TANG,Y Tom ,  BAUGHN, Mariah, R ,  HE, Ann ,  THORNTON, Michael ,  HAFALIA, April ,  PATTERSON, Chandra ,  GURURAJAN,Rajagopal ,  LO, Terence, P ,  KHAN, Farrah ,  RECIPON, Shirley, A ,  AZIMZAI, Yalda ,  POLICKY, Jennifer, L ,  DING,Li ,  GRETHER, Megan ,  ELLIOTT, Vicki, S ,  THANGAVELU, Kavitha ,  BATRA, Sajeev ,  ISON, Craig, H

IPC分类号： C12N15/54 ,  C12N9/12 ,  C07K16/40 ,  C12Q1/68 ,  G01N33/573

CPC分类号： C12N9/12

摘要： The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or prevention disorders associated with aberrant expression of PKIN.

公开(公告)号：EP1255819A2

公开(公告)日：2002-11-13

申请号：EP01910933.9

申请日：2001-02-16

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  BUFORD, Neil ,  GANDHI, Ameena, R. ,  PATTERSON, Chandra ,  KHAN, Farrah, A. ,  YUE, Henry ,  HAFALIA, April ,  SHIH, Leo, L. ,  TRIBOULEY, Catherine, M. ,  YAO, Monique, G. ,  BURRILL, John, D. ,  MARCUS, Gregory, A. ,  ZINGLER, Kurt, A. ,  LU, Dyung, Aina, M. ,  BANDMAN, Olga ,  POLICKY, Jennifer, L. ,  GRIFFIN, Jennifer, A. ,  THORNTON, Michael ,  NGUYEN, Danniel, B. ,  WALSH, Roderick, T.

IPC分类号： C12N9/12 ,  C12N15/54 ,  C12N5/10 ,  A01K67/027 ,  C07K16/40 ,  C12Q1/68 ,  C12N15/11 ,  A61K38/45 ,  G01N33/53

CPC分类号： C12N9/1205 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00

摘要： The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.

公开(公告)号：EP1442064A2

公开(公告)日：2004-08-04

申请号：EP02801802.6

申请日：2002-10-17

申请人： Incyte Genomics, Inc.

发明人： BANDMAN, Olga ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  DUGGAN, Brendan, M. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GANDHI, Ameena, R. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  HAFALIA, April, J.A. ,  KHAN, Farrah, A. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Soo, Yeun ,  LINDQUIST, Erika, A. ,  LU, Dyung Aina, M. ,  LU, Yan ,  MARQUIS, Joseph, P. ,  NGUYEN, Danniel, B. ,  ARVIZU, Chandra S. ,  RAMUKAR, Jayalaxmi ,  RECIPON, Shirley A. ,  RICHARDSON, Thomas, W. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  THORNTON, Michael ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget A. ,  YANG, Junming ,  YAO, Monique G. ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh

IPC分类号： C07K16/00 ,  A61K38/00

CPC分类号： C12N9/1205 ,  A01K2217/05

摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1412387A2

公开(公告)日：2004-04-28

申请号：EP01988245.5

申请日：2001-10-25

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  YUE, Henry ,  NGUYEN, Danniel, B. ,  HAFALIA, April, J., A. ,  ELLIOTT, Vicki, S. ,  LU, Yan ,  CHAWLA, Narinder, K. ,  YAO, Monique, G. ,  BAUGHN, Mariah, R. ,  GANDHI, Ameena, R. ,  DING, Li ,  SANJANWALA, Madhusudan ,  RAMKUMAR, Jayalaxmi ,  ARVIZU, Chandra ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  AZIMZAI, Yalda ,  KHAN, Farrah, A. ,  THANGAVELU, Kavitha ,  THORNTON, Michael ,  LU, Dyung Aina M. ,  TRIBOULEY, Catherine M. ,  WARREN, Bridget A. ,  ISON, Craig H. ,  DAS, Debopriya ,  RAUMANN, Brigitte E. ,  POLICKY, Jennifer L. ,  KEARNEY, Liam

IPC分类号： C07K14/705

CPC分类号： C07K14/705

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

公开(公告)号：EP1404703A2

公开(公告)日：2004-04-07

申请号：EP02723697.5

申请日：2002-03-29

申请人： Incyte Genomics, Inc.

发明人： THORNTON, Michael ,  YAO, Monique, G. ,  RICHARDSON, Thomas, W. ,  SWARNAKAR, Anita ,  KALLICK, Deborah, A. ,  ISON, Craig, H. ,  CHAWLA, Narinder, K. ,  GANDHI, Ameena, R. ,  LEE, Ernestine, A. ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J.A. ,  AU-YOUNG, Janice ,  GRIFFIN, Jennifer, A. ,  BAUGHN, Mariah, R. ,  KHAN, Farrah, A. ,  BECHA, Shanya ,  LU, Yan ,  ARVIZU, Chandra, S. ,  BOROWSKY, Mark, L. ,  LAL, Preeti G. ,  RAMKUMAR, Jayalaxmi ,  EMERLING, Brooke M. ,  WALSH, Roderick T. ,  YUE, Henry ,  BURFORD, Neil ,  GRAUL, Richard C.

IPC分类号： C07K5/00 ,  C07K7/00 ,  C07K14/00 ,  A61K38/00

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

公开(公告)号：EP1366165A2

公开(公告)日：2003-12-03

申请号：EP02718924.0

申请日：2002-02-06

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  TRIBOULEY, Catherine, M. ,  NGUYEN, Danniel, B. ,  THORNTON, Michael ,  YAO, Monique, G. ,  KALLICK, Deborah, A. ,  GANDHI, Ameena, R. ,  CHAWLA, Narinder, K. ,  ARVIZU, Chandra ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J., A. ,  RAMKUMAR, Jayalaxmi ,  PEI, Jin ,  TANG, Y., Tom ,  YUE, Henry ,  REDDY, Roopa, M. ,  BURFORD, Neil ,  LU, Dyung, Aina, M. ,  GRAUL, Richard, C. ,  KHAN, Farrah A. ,  WALSH, Roderick T. ,  ISON, Craig H. ,  RICHARDSON, Thomas W. ,  GRIFFIN, Jennifer A. ,  WARREN, Bridget A. ,  YANG, Junming ,  LEE, Ernestine A. ,  HARLAND, Lee

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K14/72 ,  C12N5/10 ,  C07K16/28 ,  C12Q1/68 ,  A61K38/16 ,  G01N33/50 ,  A61K31/00 ,  A61K33/00 ,  A61K39/395

CPC分类号： C07K14/723 ,  C07K14/705

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

公开(公告)号：EP1360304A2

公开(公告)日：2003-11-12

申请号：EP02718932.3

申请日：2002-02-08

申请人： Incyte Genomics, Inc.

发明人： SANJANWALA, Madhusudan, M. ,  LU, Yan ,  LEE, Ernestine, A. ,  HAFALIA, April, J. A. ,  WARREN, Bridget, A. ,  BAUGHN, Mariah, R. ,  TANG, Tom, Y. ,  YUE, Henry ,  YAO, Monique, G. ,  LEE, Sally ,  THORNTON, Michael ,  CHAWLA, Narinder, K. ,  XU, Yuming ,  TRAN, Uyen, K. ,  LAL, Preeti, G. ,  LU, Dyung, Aina, M. ,  SWARNAKER, Anita ,  JONES, Karen, Anne ,  RING, Huijun, Z.

IPC分类号： C12N15/54 ,  C12N9/10 ,  A01K67/027 ,  C07K16/40 ,  C12Q1/68 ,  A61K38/43 ,  G01N33/68 ,  C12Q1/48 ,  A61K49/00 ,  G01N33/53

CPC分类号： C12N9/0004 ,  A61K38/00 ,  C12N9/10 ,  C12N9/88 ,  G01N33/573

摘要： The invention provides human enzymes (NZMS) and polynucleotides which identify and encode NZMS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NZMS.

摘要翻译： 本发明提供了识别和编码NZMS的人类酶（NZMS）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与NZMS异常表达相关的病症的方法。

公开(公告)号：EP1341921A2

公开(公告)日：2003-09-10

申请号：EP01975504.0

申请日：2001-09-28

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  BAUGHN, Mariah, R. ,  WARREN, Bridget, A. ,  TRIBOULEY, Catherine, M. ,  TANG, Y., Tom ,  KHAN, Farrah, A. ,  YAO, Monique, G. ,  LAL, Preeti ,  THORNTON, Michael

IPC分类号： C12N15/55 ,  C12N9/14 ,  C07K16/40 ,  G01N33/573 ,  G01N33/577 ,  C12Q1/34 ,  C12Q1/68 ,  A61K38/46 ,  A61K39/395 ,  C12N1/21 ,  C12N1/15 ,  C12N5/10 ,  A01K67/027 ,  A01H5/00

CPC分类号： C12N9/14 ,  A01K2217/05 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human hydrolases (HYDR) and polynucleotides which identify and encode HYDR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HYDR.

摘要翻译： 本发明提供了识别和编码HYDR的人水解酶（HYDR）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与HYDR异常表达相关的病症的方法。

公开(公告)号：EP1339748A2

公开(公告)日：2003-09-03

申请号：EP01999578.6

申请日：2001-12-05

申请人： Incyte Genomics, Inc.

发明人： KALLICK, Deborah, A. ,  BAUGHN, Mariah, R. ,  LU, Dyung, Aina, M. ,  YUE, Henry ,  GRAUL, Richard, C. ,  LU, Yan ,  DING, Li ,  TRIBOULEY, Catherine, M. ,  TANG, Y., Tom ,  GANDHI, Ameena, R. ,  THORNTON, Michael

IPC分类号： C07K14/705 ,  C12N15/12 ,  C12N1/21 ,  C12N5/10 ,  A01K67/027 ,  C12N15/00 ,  C07K16/28 ,  C12Q1/68 ,  A61K38/17 ,  G01N33/68

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/723

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

公开(公告)号：EP1326972A2

公开(公告)日：2003-07-16

申请号：EP01971080.5

申请日：2001-09-14

申请人： Incyte Genomics, Inc.

发明人： LEE, Ernestine, A. ,  YUE, Henry ,  LAL, Preeti, G. ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  WARREN, Bridget, A. ,  LEE, Sally ,  SANJANWALA, Madhu, S. ,  YAO, Monique, G. ,  RAMKUMAR, Jayalaxmi ,  THORNTON, Michael ,  GANDHI, Ameena, R. ,  POLICKY, Jennifer, L. ,  ELLIOTT, Vicki, S. ,  ARVIZU, Chandra ,  RAUMANN, Brigitte, E. ,  BRUNS, Christopher, M. ,  NAINI, Amir ,  HAFALIA, April, J., A. ,  NGUYEN, Danniel B. ,  XU, Yuming ,  LU, Dyung Aina M. ,  ISON, Craig H. ,  GRIFFIN, Jennifer A. ,  REDDY, Roopa M. ,  BURFORD, Neil

IPC分类号： C12N15/12 ,  C12N5/10 ,  C12Q1/68 ,  C07K14/705 ,  C07K16/18 ,  C07K1/22 ,  A61K38/17 ,  A01K67/027 ,  G01N33/68 ,  G01N33/53 ,  B01J19/00

CPC分类号： C07K14/705

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.