公开(公告)号：EP0513966A3

公开(公告)日：1993-03-03

申请号：EP92301575.4

申请日：1992-02-25

Applicant: ZENECA LIMITED

Inventor： Quan, Peter Michael ,  Thorp, Derek ,  Dalton, Raymond Frederick

IPC: C07D235/20 ,  C22B3/00 ,  C07D487/04

CPC classification number: C07D487/14 ,  C07D235/20 ,  C22B3/0036 ,  Y02P10/234 ,  Y10S423/14

Abstract: A composition of bibenzimidazoles of the Formula (I) :

wherein
X&Y which may be the same or different and, taken together, contain a total of from 12 to 52 saturated carbon atoms, are (a) each selected from -R, -COR, -CH 2 COOR, -CH(COOR) 2 and -COOR; or (b) together form a group selected from

and

wherein R is an optionally substituted hydrocarbyl group, A & B taken together with the two carbon atoms to which they are linked form an optionally substituted benzene ring ; and C & D taken together with the two carbon atoms to which they are linked form an optionally substituted benzene ring ; characterised in that at least 50% by weight of the bibenzimidazoles in the composition are of Formula (II)
wherein X and Y are as hereinbefore defined ; T, U, V & W which may be the same or different, are H, R 1 or OR 1 provided at least one of T, U, V & W is R 1 or OR 1 ; and R 1 is C 1-6 -alkyl ; which are suitable for use in the extraction of zinc from aqueous solutions of zinc in the presence of other metals.

Abstract translation: 式（I）的联苯并咪唑的组合物：其中可以相同或不同并且一起含有总共12至52个饱和碳原子的X和Y是（a）各自选自-R，-COR， -CH 2 COOR，-CH（COOR）2和-COOR; 或（b）一起形成选自和其中R是任选取代的烃基的基团，A和B与它们所连接的两个碳原子一起形成任选取代的苯环; 并且C＆D与它们连接的两个碳原子一起形成任选取代的苯环; 其特征在于组合物中至少50重量％的联苯并咪唑类具有式（II），其中X和Y如上所定义; T，U，V和W可以相同或不同，为H，R1或OR1，条件是T，U，V和W中至少一个为R1或OR1; 和R1是C1-6-烷基; 它们适用于在存在其他金属的情况下从锌水溶液中提取锌。

公开(公告)号：EP0268553B1

公开(公告)日：1991-09-11

申请号：EP87810585.7

申请日：1987-10-12

Applicant: CIBA-GEIGY AG

Inventor： Bauer, Sigrid, Dr.

IPC: C07D235/20 ,  C07D249/18 ,  G03F7/16

CPC classification number: C07D249/18 ,  C07D235/20 ,  G03F7/022

公开(公告)号：EP0009163A3

公开(公告)日：1980-04-16

申请号：EP79103260

申请日：1979-09-04

Applicant: HOECHST AKTIENGESELLSCHAFT

Inventor： Rösner, Manfred, Dr. ,  Raether, Wolfgang, Dr.

IPC: C07D235/20 ,  C07D407/04 ,  C07D409/04 ,  A61K31/415 ,  C07D333/38 ,  C07D307/68 ,  C07C87/60 ,  C07C87/58 ,  C07D295/12

CPC classification number: C07D295/195 ,  C07D235/20 ,  C07D307/68 ,  C07D333/38

公开(公告)号：EP3293292A1

公开(公告)日：2018-03-14

申请号：EP17182525.0

申请日：2014-08-08

Applicant: The Scripps Research Institute

Inventor： DISNEY, Matthew D. ,  VELAGAPUDI, Sai

IPC: C40B30/02 ,  C40B30/04 ,  C40B30/06

CPC classification number: G06F19/16 ,  C07D235/18 ,  C07D235/20 ,  C07D403/14 ,  C07H15/04 ,  C07H15/234 ,  G01N33/5308 ,  G01N2500/04 ,  G06F19/22

Abstract: Methods and computer systems are described herein for identifying small molecules that bind to selected RNA structural features (e.g., to RNA secondary structures). Also described are compounds and compositions that modulate RNA function and/or activity.

Abstract translation: 本文描述了用于鉴定结合选定RNA结构特征（例如结合RNA二级结构）的小分子的方法和计算机系统。 还描述了调节RNA功能和/或活性的化合物和组合物。

公开(公告)号：EP3224249A1

公开(公告)日：2017-10-04

申请号：EP15863016.0

申请日：2015-10-20

Applicant: Canon Kabushiki Kaisha

Inventor： KAMATANI, Jun ,  NISHIDE, Yosuke ,  MIYASHITA, Hirokazu ,  YAMADA, Naoki

IPC: C07D235/20 ,  C07D235/30 ,  C07D409/14 ,  C09K11/06 ,  H01L51/50 ,  H05B33/08

CPC classification number: H01L51/0072 ,  C07D235/20 ,  C07D401/14 ,  C07D409/14 ,  C09B23/102 ,  C09B57/00 ,  G03G15/04036 ,  H01L27/1225 ,  H01L27/3262 ,  H01L29/7869 ,  H01L51/0058 ,  H01L51/0074 ,  H01L51/5012 ,  H01L51/5092 ,  H01L51/5206 ,  H01L51/5221 ,  H01L51/529 ,  H05B33/0896

Abstract: A stable 2,2'-bibenzo[d]imidazolidene compound is provided. The 2,2'-bibenzo[d]imidazolidene compound is expressed by the following General Formula (1). In General Formula (1), Ar1 to Ar8 each represent a substituted or unsubstituted condensed ring. R1 to R8 each represent a hydrogen atom or a substituent.

Abstract translation: 提供稳定的2,2'-联苯并[d]咪唑化合物。 2,2'-联苯并[d]咪唑啉化合物由以下通式（1）表示。 通式（1）中，Ar 1〜Ar 8分别表示取代或未取代的稠环。 R1至R8各自表示氢原子或取代基。

公开(公告)号：EP3160944A1

公开(公告)日：2017-05-03

申请号：EP15811076.7

申请日：2015-06-22

Applicant: Canon Kabushiki Kaisha

Inventor： KAMATANI, Jun ,  KOSUGE, Tetsuya ,  ITABASHI, Masumi ,  NISHIDE, Yosuke ,  MIYASHITA, Hirokazu ,  YAMADA, Naoki ,  TAKAHASHI, Tetsuo ,  SHIOBARA, Satoru

IPC: C07D235/20 ,  H01L51/50 ,  H05B33/12

CPC classification number: H01L51/0072 ,  C07D235/20 ,  F21V29/70 ,  F21Y2115/15 ,  G03G15/04054 ,  G03G2215/0409 ,  G09G3/3208 ,  H01L27/322 ,  H01L27/3244 ,  H01L29/24 ,  H01L29/7869 ,  H01L51/504 ,  H01L51/5072 ,  H01L51/5092 ,  H05B33/0896

Abstract: A bibenzo[d]imidazolidene compound inert to oxygen is provided. An aspect of the invention provides a 1,1',3,3'-tetraphenyl-2,2'-bibenzo[d]imidazolidene compound according to Claim 1, which is represented by general formula (1). In formula (1), R1 to R28 are each independently selected from a hydrogen atom and a substituent. The substituent is any of a halogen atom, an alkyl group containing 1 or more and 8 or less carbon atoms, and a substituted or unsubstituted aryl group. At least one of R1 to R28 is the substituent.

Abstract translation: 本发明提供一种bibenzo并[d] imidazolidene化合物惰性的氧。 本发明的一个方面提供了一种1,1”，3,3'-四苯基-2,2'- bibenzo并[d] imidazolidene化合物gemäß权利要求1，在所有其由通式（1）表示。 在式（1）中，R1〜R28分别独立地选自氢原子和取代基中选择。 该取代基是任何卤原子的烷基含1以上且8个以下的碳原子，和一个substituiertem奥德unsubstituiertem芳基团。 至少R1中的一个来R28是取代基。

公开(公告)号：EP2318376B1

公开(公告)日：2015-07-29

申请号：EP09791236.4

申请日：2009-08-06

Applicant: Bristol-Myers Squibb Company

Inventor： BELEMA, Makonen ,  GOOD, Andrew, C. ,  GOODRICH, Jason ,  KAKARLA, Ramesh ,  LI, Guo ,  LOPEZ, Omar, D. ,  NGUYEN, Van, N. ,  KAPUR, Jayne ,  QIU, Yuping ,  ROMINE, Jeffrey, Lee ,  ST. LAURENT, Denis, R. ,  SERRANO-WU, Michael ,  SNYDER, Lawrence, B. ,  YANG, Fukang

IPC: C07D235/20 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  A61K31/4184 ,  A61K31/4188 ,  A61P31/12 ,  C07D409/14

CPC classification number: C07D235/20 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

公开(公告)号：EP2864299A1

公开(公告)日：2015-04-29

申请号：EP13728403.0

申请日：2013-06-14

Applicant: Janssen Sciences Ireland UC

Inventor： TAHRI, Abdellah ,  JONCKERS, Tim, Hugo, Maria ,  RABOISSON, Pierre, Jean-Marie, Bernard ,  VENDEVILLE, Sandrine, Marie Helene ,  HU, Lili

IPC: C07D235/20 ,  C07D235/26 ,  C07D471/04 ,  A61K31/437 ,  A61K31/4184 ,  A61P11/00

CPC classification number: C07D487/04 ,  C07D235/20 ,  C07D235/26 ,  C07D471/04

Abstract: The present invention is concerned with novel 4-substituted 1,3-dihydro-2H- benzimidazol-2-one derivatives substituted with benzimidazoles having formula (I), tautomers and stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherein R
4 , R
5 , Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.

公开(公告)号：EP2803356A1

公开(公告)日：2014-11-19

申请号：EP14166640.4

申请日：2009-03-31

Applicant: Agency for Science, Technology and Research

Inventor： Zhuo, Lang ,  Ho, Gideon ,  Zhang, Yugen ,  Ying, Jackie Y.

IPC: A61K31/4164 ,  C07D233/06 ,  C07D249/16 ,  A61K31/4184 ,  C07D233/58 ,  C07D401/04 ,  A61K31/4196 ,  C07D233/60 ,  C07D401/14 ,  A61P25/16 ,  C07D233/61 ,  A61P25/18 ,  C07D235/20

CPC classification number: A61K31/4164 ,  A61K31/4174 ,  A61K31/4184 ,  A61K31/4196 ,  C07D233/06 ,  C07D233/58 ,  C07D233/60 ,  C07D233/61 ,  C07D235/20 ,  C07D249/16 ,  C07D401/04 ,  C07D401/14

Abstract: There is presently provided methods for delivering a neuroprotective agent to a neural cell. The methods comprise contacting a neural cell with an imidazolium or imidazolinium compound as described herein, including an imidazolium or imidazolinium salt.

Abstract translation: 目前提供了将神经保护剂递送至神经细胞的方法。 所述方法包括将神经细胞与如本文所述的咪唑鎓或咪唑啉化合物接触，包括咪唑鎓或咪唑啉鎓盐。

公开(公告)号：EP2445888B1

公开(公告)日：2013-08-07

申请号：EP10727386.4

申请日：2010-06-17

Applicant: INKE, S.A.

Inventor： SINGH, Santosh ,  JOSHI, Anil ,  NEWADKAR, Ravindranath

IPC: C07D235/20

CPC classification number: C07D235/20