公开(公告)号：EP2459726A1

公开(公告)日：2012-06-06

申请号：EP10725576.2

申请日：2010-06-15

申请人： MBI International

发明人： GUETTLER, Michael, V. ,  HANCHAR, Robert, J. ,  RUMLER, Denise, S. ,  KLEFF, Susanne

IPC分类号： C12P7/46

CPC分类号： C12P7/56 ,  C12P7/46 ,  C12P7/48

摘要： This invention is directed to methods of obtaining a high quantity of desired acid salt in a form that is relatively easy to recover. Particularly desired as a recovery product is an organic acid. A salt form of the desired organic acid is formed that is relatively high in concentration and that is relatively soluble in an aqueous medium. The method includes a step of fermenting a fermentable carbon source in the fermentation medium in the presence of a magnesium compound containing oxygen.

摘要翻译： 本发明涉及以相对容易恢复的形式获得大量所需酸盐的方法。 作为回收产物特别需要的是有机酸。 形成浓度相对较高并且相对可溶于水性介质的所需有机酸的盐形式。 该方法包括在含有氧化镁的化合物的存在下在发酵培养基中发酵可发酵碳源的步骤。

公开(公告)号：EP2118295A2

公开(公告)日：2009-11-18

申请号：EP08717464.5

申请日：2008-03-06

申请人： DSM IP Assets B.V.

发明人： BAUWELEERS, Hugo Marc Karel ,  GROESENEKEN, Dominique Robert

IPC分类号： C12P7/48 ,  C07C31/22

CPC分类号： C12P7/48 ,  C07C29/88 ,  C07C31/225

摘要： The present invention relates to a method for producing citric acid from glycerol with a yield of more than 70%. The method comprises fermenting a filamentous fungus on a substrate which comprises glycerol. The advantage of the method according to the invention is that a widely available substrate, i.e. glycerol, can be used and that yields may be obtained which are much higher than the yields obtained using state of the art methods for producing citric acid from glycerol. The glycerol is used in combination with one or more other carbon sources.

公开(公告)号：EP1789567A2

公开(公告)日：2007-05-30

申请号：EP05776873.1

申请日：2005-08-31

申请人： Agrotechnology and Food Innovations B.V.

发明人： SANDERS, Johan, Pieter, Marinus ,  WEUSTHUIS, Ruud, Alexander ,  MOOIBROEK, Andreas

IPC分类号： C12P1/00 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/56 ,  C12P7/58 ,  C12P7/64 ,  C12P13/06 ,  C12P13/08 ,  C12P13/14 ,  C12P37/00 ,  C12M1/12

CPC分类号： C12P7/56 ,  C12P1/00 ,  C12P7/46 ,  C12P7/48 ,  C12P7/54 ,  C12P7/58 ,  C12P7/6409 ,  C12P7/6427 ,  C12P7/6463 ,  C12P7/6472 ,  C12P13/06 ,  C12P13/08 ,  C12P13/14 ,  C12P37/00

摘要： The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by a single production organism wherein the first product is in a more reduced state than the substrate and the second fermentation product is in a more oxidised state than the substrate yet in less oxidised state than the final oxidation product CO2, such that the concurrent synthesis of the first and second product in the organism allows recycling of reducing power and can be performed under (partially) anaerobic conditions. The invention further relates to processes in which the first fermentation product is weak alkaline compound and the second fermentation product is a weak acidic compound. In such instances both products may be produced by a single organism in a single fermenter or each the first and second product may be produced by two different organisms that are co-fermented. Co-fermentation may be performed in two separate fermenters that are connected through micro-sieves that allow circulation of soluble medium components between the two fermenters but prevent circulation of the production organisms' cells. The invention also relates to such processes in which the first and second fermentation products are capable of forming a(n) (insoluble) complex or salt.

公开(公告)号：EP1183385B1

公开(公告)日：2006-07-19

申请号：EP00932649.7

申请日：2000-05-19

申请人： Cargill Dow LLC

发明人： RAJGARHIA,Vineet ,  HATZIMANIKATIS, Vassily ,  OLSON, Stacey ,  CARLSON, Ting Liu ,  STARR, John N. ,  KOLSTAD, Jeffrey J. ,  EYAL, Aharon, M.

IPC分类号： C12P7/56 ,  C12P7/40 ,  C12P7/48 ,  C12P7/60 ,  C12P19/02 ,  C12N15/53 ,  C12N15/81 ,  C12N9/04 ,  C12N1/19 ,  C12R1/645

CPC分类号： C12N1/16 ,  C12P7/40 ,  C12P7/48 ,  C12P7/56 ,  C12P7/60 ,  Y02E50/17

摘要： The invention provides methods and materials related to the production of organic products. Specifically, the invention provides various recombinant yeast cells, methods for culturing yeast cells, methods for making yeast cells, nucleic acid constructs, and methods and materials for producing various organic products.

公开(公告)号：EP0611823B1

公开(公告)日：1999-11-24

申请号：EP94102443.2

申请日：1994-02-17

申请人： KEMIJSKI INSTITUT

发明人： Legisa, Matic, Dr. ,  Gradisnik-Grapulin, Majda

IPC分类号： C12P7/48

CPC分类号： C12P7/48

公开(公告)号：EP0479084A2

公开(公告)日：1992-04-08

申请号：EP91116121.4

申请日：1991-09-23

申请人： HAARMANN & REIMER CORP.

发明人： Mothes, Helmut A. ,  Patwardhan, Bhalchandra H. ,  Schroeder, Theo G. ,  Solow, David J.

IPC分类号： C07C59/265 ,  C07C51/43 ,  C07C51/42

CPC分类号： C12P7/48 ,  C07C51/42 ,  C07C51/43 ,  Y10S435/80 ,  Y10S435/917 ,  Y10S435/923 ,  C07C59/265

摘要： Disclosed is an improved method for preparing a particulate citric acid or an alkali metal or alkaline earth metal salt thereof. The method involves spray granulating citric acid or a salt thereof from its partially purified fermentation broth to form granules which are freer flowing and less inclined to fracture than is citric acid or its salts prepared by crystallization techniques which properties render the material prepared by the present method suitable for handling in bulk.

摘要翻译： 公开了一种制备颗粒状柠檬酸或其碱金属或碱土金属盐的改进方法。 该方法包括从其部分纯化的发酵液中将柠檬酸或其盐喷雾成粒，以形成比柠檬酸或其盐通过本发明方法制备的材料通过结晶技术制备的柠檬酸或其盐更自由流动并且不太倾向于断裂的颗粒 适合批量处理。

公开(公告)号：EP0460854A1

公开(公告)日：1991-12-11

申请号：EP91304805.4

申请日：1991-05-28

申请人： CARGILL, INCORPORATED

发明人： Baniel, Avraham ,  Gonen, David

IPC分类号： C07C59/265 ,  C07C51/48 ,  C12P7/48 ,  A23K1/16

CPC分类号： C12P7/48 ,  C07C51/48 ,  C07C59/265

摘要： A process for the recovery of citric acid from a citric acid fermentation broth comprising

i) subjecting said citric acid fermentation broth to evaporation to produce a concentrate;
ii) subjecting such concentrate to an extraction operation with a recycled amine extractant citric acid solution;
iii) withdrawing the aqueous extraction raffinate from said extraction operation;
iv) withdrawing the said concentrated amine extractant citric acid solution extract and back-extracting it with water to obtain an aqueous citric acid solution and a depleted amine extractant citric acid solution; and
v) recycling said depleted amino extractant citric acid solution to the extraction operation.

摘要翻译： 一种从柠檬酸发酵液中回收柠檬酸的方法，包括：i）使所述柠檬酸发酵液蒸发以产生浓缩物; ii）用再循环的胺萃取剂柠檬酸溶液对这种浓缩物进行萃取操作; iii）从所述提取操作中抽出含水萃取萃余液; iv）取出所述浓胺萃取剂柠檬酸溶液提取物并用水反萃，得到柠檬酸水溶液和贫胺萃取剂柠檬酸溶液; 和v）将所述耗尽的氨基提取剂柠檬酸溶液回收至萃取操作。 [R

公开(公告)号：EP0135728B1

公开(公告)日：1987-11-11

申请号：EP84109154.9

申请日：1984-08-02

申请人： HOECHST AKTIENGESELLSCHAFT

发明人： Keil, Karl-Heinz, Dr. ,  Greiner, Ulrich, Dr. ,  Engelhardt, Friedrich, Dr. ,  Kühlein, Klaus, Dr. ,  Hess, Gerhard ,  Keller, Reinhold, Dr. ,  Schlingmann, Merten, Dr.

IPC分类号： C07C51/47 ,  C07C59/08 ,  C07C59/265 ,  C08F226/00

CPC分类号： C12P7/56 ,  C07C51/47 ,  C12P7/48 ,  C07C59/08 ,  C07C59/265

公开(公告)号：EP0052829A3

公开(公告)日：1982-07-21

申请号：EP81109609

申请日：1981-11-11

申请人： MILES LABORATORIES, INC.

发明人： Borglum, Gerald Baltzer

IPC分类号： C12N11/04 ,  C12N11/10 ,  C12P07/06 ,  C12P07/48

CPC分类号： C12N11/10 ,  C12N11/04 ,  C12P7/06 ,  C12P7/48 ,  Y02E50/17

摘要： A method for immobilizing viable microorganisms in kappa-carrageenan is disclosed. The method involves mixing the microorganisms and kappa-carrageenan together and gelling the mixture with an epihalohydrin alkylene polyamine polymer or with polyethyleneimine. Also disclosed are methods of producing citric acid and ethanol from immobilized microorganisms.

公开(公告)号：EP3133164A4

公开(公告)日：2018-01-03

申请号：EP15780585

申请日：2015-04-10

申请人： TORAY INDUSTRIES

发明人： KOBAYASHI KOJI ,  SAWAI KENJI ,  YAMADA KATSUSHIGE

IPC分类号： C12P7/06 ,  C12P7/16 ,  C12P7/18 ,  C12P7/40 ,  C12P7/46 ,  C12P7/48 ,  C12P7/50

CPC分类号： C12P7/56 ,  C12P7/06 ,  C12P7/16 ,  C12P7/18 ,  C12P7/46 ,  C12P7/48 ,  C12P7/50 ,  Y02E50/17

摘要： A method for producing a chemical product by continuous fermentation utilizing a separation membrane under conditions at a pH of not more than 3.5, wherein yeast having vanillin resistance is used to enable efficient production of a chemical product without leaving a large amount of fermentation feedstock unused, is provided.