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423 条记录 (耗时 0.023 秒)

    A PROCESS FOR THE HYDROGENATION OF A SUGAR OR SUGAR MIXTURE
    31.
    发明公开
    A PROCESS FOR THE HYDROGENATION OF A SUGAR OR SUGAR MIXTURE 有权
    工艺加氢的糖或糖混纺

    公开(公告)号：EP2104658A1

    公开(公告)日：2009-09-30

    申请号：EP07857108.0

    申请日：2007-12-21

    申请人： Cargill, Incorporated

    发明人： WEICHERT, Udo

    IPC分类号： C07C29/141 ,  C07C29/145 ,  C07H3/00 ,  C07H3/04 ,  C07H1/00

    CPC分类号： C07H3/00 ,  C07H1/00 ,  C07H3/04

    摘要： A process for the hydrogenation of a ketose or a ketose-containing sugar mixture to produce a product mixture comprising at least two stereoisomeric sugar alcohols is disclosed. The process comprises the provision of a reaction mixture comprising said ketose or ketose-containing sugar mixture, the addition of a concentration of solid nickel-based catalyst to said reaction mixture, and conducting a hydrogenation reaction in said reaction mixture in the presence of hydrogen gas. With this process, it is possible to obtain a predefined ratio of cis-isomer to trans-isomer of the two stereoisomeric sugar alcohols. The ratio of cis-isomer to trans-isomer can be decreased by increasing the concentration of solid nickel-based catalyst, by decreasing the starting temperature of the heating step, and/or by decreasing the heating rate of the heating step.

    SOLID- AND SOLUTION -PHASE SYNTHESIS OF HEPARIN AND OTHER GLYCOSAMINOGLYCANS
    32.
    发明公开
    SOLID- AND SOLUTION -PHASE SYNTHESIS OF HEPARIN AND OTHER GLYCOSAMINOGLYCANS 审中-公开
    肝素及其他粘多糖固相和液相合成

    公开(公告)号：EP1353556A4

    公开(公告)日：2009-09-09

    申请号：EP02709129

    申请日：2002-01-22

    申请人： MASSACHUSETTS INST TECHNOLOGY

    发明人： SEEBERGER PETER H ,  ORGUEIRA HERNAN ,  SCHELL PETER

    IPC分类号： C07H3/04 ,  A01N43/04 ,  A61K31/715 ,  C07H3/06 ,  C08B37/00

    CPC分类号： C07H3/06 ,  C07H3/04 ,  C08B37/0075

    摘要： Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of each of them. Additionally, the modular strategy provides the basis for the preparation of combinatorial libraries and parallel libraries of defined glycosaminoglycan oligosaccharides. The defined glycosaminoglycan structures may be used in high-throughput screening experiments to identify carbohydrate sequences that regulate a host of recognition and signal-transduction processes. The determination of specifi sequences involved in receptor binding holds great promise for the develpment of molecular tools which will allow modulation of processes underlying viral entry, angiog enesis, kidney diseases and diseases of the control nervous system. Notably, the present invention enables the automated synthesis of glycosaminoglycans in much the same fashion that peptides and oligonucleotides are currently assembled.

    beta-1,4-MANNOBIOSE-CONTAINING COMPOSITION
    35.
    发明公开
    beta-1,4-MANNOBIOSE-CONTAINING COMPOSITION 有权
    β-1,4-甘露二糖包括成分

    公开(公告)号：EP1566446A4

    公开(公告)日：2008-12-31

    申请号：EP03775906

    申请日：2003-11-26

    申请人： FUJI OIL CO LTD

    发明人： MORIKOSHI TOSHIMICHI ,  YOKOMIZO FUTOSHI

    IPC分类号： A23K1/16 ,  A23K1/18 ,  A23L1/0528 ,  A61K31/7016 ,  A61P31/04 ,  C07H3/04 ,  C12P19/12 ,  C12P19/14

    CPC分类号： A23K1/1826 ,  A23K20/163 ,  A23K50/75 ,  A23L29/244 ,  A61K31/7016 ,  C07H3/04 ,  C12P19/12 ,  C12P19/14 ,  Y10S424/823 ,  Y10S424/826

    摘要： It is intended to provide a process for producing a composition containing beta-1,4-mannobiose which can inhibit the fixation of salmonella in animal bodies and effectively discharge the salmonella therefrom; a feed additive comprising the composition containing beta-1,4-mannobiose; and a feed comprising the composition containing beta-1,4-mannobiose. Namely, a process for producing a composition containing beta-1,4-mannobiose characterized by comprising treating a natural material containing mannan with a mannan digesting enzyme and thus forming at least 10% by weight, based on the mannan before the digestion, of beta-1,4-mannobiose; a composition containing beta-1,4-mannobiose characterized by being obtained by treating a natural material containing mannan with a mannan digesting enzyme and containing at least 10% by weight, in terms of dry matter, of beta-1,4-mannobiose; a feed additive comprising the composition containing beta-1,4-mannobiose; and a feed comprising the composition containing beta-1,4-mannobiose.

    LIQUID FOR PREVENTING TISSUE ADHESION AND METHOD OF PREVENTING TISSUE ADHESION
    37.
    发明公开
    LIQUID FOR PREVENTING TISSUE ADHESION AND METHOD OF PREVENTING TISSUE ADHESION 有权
    FLÜSSIGKEITENTHALTEND TREHALOSE ZUR VERWENDUNG BEI DER PREVENTION VONGEWEBEADHÄSION

    公开(公告)号：EP1905443A1

    公开(公告)日：2008-04-02

    申请号：EP06766477.1

    申请日：2006-06-08

    申请人： Cellex K.K. ,  KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO ,  The University of Tokyo

    发明人： SUZUKI, Shigeki ,  MIWA, Yoshikatsu K.K.K. Seibutsu Kagaku Kenkyujo ,  SASAKI, Nobuo c/o THE UNIVERSITY OF TOKYO ,  TEI, Yuichi c/o THE UNIVERSITY OF TOKYO

    IPC分类号： A61K31/7016 ,  A61P41/00 ,  C07H3/04

    CPC分类号： A61K31/7016 ,  A61L31/042

    摘要： The objective of the invention is to provide a solution for tissue adhesion prevention and a method for tissue adhesion prevention that are applicable to general surgery and in which covering condition during surgery is stable and convenient.
    The invention is the solution for tissue adhesion prevention of which the active ingredient is trehalose. Also, it contains at least one or more among antioxidants, chelates, antiseptics, hemostatics, anti-inflammatory agents, and polysaccharides, mucopolysaccharides, salts of polysaccharides and salts of mucopolysaccharides having lubricating properties. This solution for tissue adhesion prevention is provided as any form of perfusion fluid, spray fluid, solution for spray or vaporization administration, foam-like aerosol preparation, injection solution for intravenous fluids, intravenous fluid.

    摘要翻译： 本发明的目的是提供一种适用于普通外科手术的组织粘连防止方法和组织粘连防止方法，其中手术中的覆盖状态是稳定和方便的。 本发明是用于组织粘附防止的方法，其中活性成分是海藻糖。 此外，它还含有抗氧化剂，螯合物，防腐剂，止血剂，抗炎剂和多糖中的至少一种或多种，​​粘多糖，多糖的盐和具有润滑性质的粘多糖的盐。 用于组织粘附防止的这种解决方案提供为任何形式的灌注液，喷雾液，用于喷雾或蒸发给药的溶液，泡沫样气溶胶制剂，静脉注射液注射液，静脉注射液。