摘要:
Systems and methods of inducing large-scale optical transfection and generation of an immune response in target cells are presented. In preferred aspects large-scale optofection uses nanoparticles with target specific affinity moieties to generate cavitation events proximal to the cell membrane of cells to which the nanoparticles are attached, and suspended and/or dissolved cargo is so provided access into the cell. Notably, cells can be transfected in very large quantities at high viability, with the transfected cells exhibiting up-regulated immune responses.
摘要:
Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only.
摘要:
Methods of detecting anomalous behaviors associated with a fabric are presented. A network fabric can comprise many fungible networking nodes, preferably hybrid-fabric apparatus capable of routing general purpose packet data and executing distributed applications. A nominal behavior can be established for the fabric and represented by a baseline vector of behavior metrics. Anomaly detection criteria can be derived as a function of a variation from the baseline vector based on measured vectors of behavior metrics. Nodes in the fabric can provide a status for one or more anomaly criterion, which can be aggregated to determine if an anomalous behavior has occurred, is occurring, or is about to occur.
摘要:
Link association analysis systems are presented. Disclosed systems are configured to analyze links created by users and to determine possible reasons underpinning why a user would create such a link. The system derives such reasons by analyzing the context within which the link was created and to which the link points, and then presents the reasons as a data object to users for feedback. The system can be made to be self-refining by collecting survey data regarding its accuracy, so that the more users interact with the system, the more accurate the system is at deriving reasons for link creation.
摘要:
Method of retrieving event information is presented. Memento objects can be recognized by an archive engine. Based on the recognition, the archive engine obtains information related to the memento object, possibly one or more recognizable features, and uses the information to search for events associated with a timeline that have corresponding tags. The archive engine can then return the event information as a result set to a user.
摘要:
A method of interacting with a virtual space, comprising: allowing a mobile device to electronically capture image data of a real-world object and a user; using the image data to identify information related to the real-world object, where the identified information includes a real-world visual appearance of the real-world object; interacting with software being operated at least in part on the device by deriving a real-world position and orientation of the object with respect to user from the real-world visual appearance of the real-world object in the identified information; and controlling interactive advertisement content on a publicly available information kiosk local to the device as a function of the real-world visual appearance of the real-world object including the derived position and orientation of the real-world object relative to the user.
摘要:
Healthcare object (HCO) discriminator systems and methods are presented. Systems can obtain a digital representation of a scene via a sensor interface. An HCO discriminator platform analyzes the digital representation to discriminate objects within the scene as being associated with a type of HCO or as being unrelated to a type of HCO. Once the HCO recognition platform determines that a type of HCO is relevant, it instantiates an actual HCO. The HCO can be routed to one or more destinations based on routing rules generated from a template or based on the manner in which the objects in the scene were discriminated.
摘要:
Interference-based augmented reality hosting platforms are presented. Hosting platforms can include networking nodes capable of analyzing a digital representation of scene to derive interference among elements of the scene. The hosting platform utilizes the interference to adjust the presence of augmented reality objects within an augmented reality experience. Elements of a scene can constructively interfere, enhancing presence of augmented reality objects; or destructively interfere, suppressing presence of augmented reality objects.