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41.发明授权VERFAHREN ZUR GEWINNUNG EINES AN NICHT-KONJUGIERTEN LIPOPHILEN VERBINDUNGEN ABGEREICHERTEN NAT RLICHEN GEMISCHES KONJUGIERTER EQUINER STROGENE 有权程序为获得TO非共轭亲脂性CONNECTIONS耗尽合剂自然科学结合雌激素
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42.发明公开A PROCESS FOR THE ISOLATION OF PHARMACOLOGICALLY ACTIVE PRINCIPLES OF VEGETABLE AND ANIMAL ORIGIN 审中-公开式分离方法的药剂PFANZLICHER和动物源
公开(公告)号：EP1965880A1
公开(公告)日：2008-09-10
申请号：EP06829732.4
申请日：2006-12-19
申请人： Evultis S.A.
发明人： MAZZOLA, Giancarlo , ANZANI, Anna
CPC分类号： B01J20/26 , A23L33/105 , A61K36/48 , B01D15/00 , B01D15/08 , B01J20/264 , B01J20/267 , C07D311/40
摘要： A process for the recovery and purification of natural hydrophilic water-soluble products in conjugated form from vegetable aqueous extracts or physiological fluids, by adsorption of said extracts or fluids on a lipophilic resin, followed by desorption and recovery of the eluate, which process is characterized in that the resin is a porous styrene-divinyl benzene polymer brominated at the styrene and/or divinylbenzene portion, with 600 m2/g area, 1.3 ml/g volume (dry weight), about 200 Angstrom pore size.
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43.发明公开
公开(公告)号：EP1539930A4
公开(公告)日：2006-08-09
申请号：EP03772114
申请日：2003-07-29
申请人： ES CELL INT PTE LTD
IPC分类号： A61K35/12 , A61K35/14 , A61K35/22 , A61K35/23 , A61K35/28 , A61K35/30 , A61K35/32 , A61K35/34 , A61K35/36 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/42 , A61K35/54 , A61P1/18 , A61P3/10 , C12N5/074 , C12N5/00 , C12N5/08 , C12N5/16
CPC分类号： C12N5/0678 , A61K35/12 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2501/01 , C12N2501/119 , C12N2501/12 , C12N2501/16 , C12N2501/175 , C12N2501/33 , C12N2501/335 , C12N2501/355 , C12N2501/39 , C12N2501/41 , C12N2501/835 , C12N2501/91
摘要： The present invention provides improved methods of differentiating insulin+, glucose responsive islet-like structures from insulin- cells. The invention further provides methods for using insulin+, glucose responsive islet-like structures, as well as the insulin+, glucose responsive cells which comprise said islet-like clusters.
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公开(公告)号：EP1446015A4
公开(公告)日：2005-11-23
申请号：EP02801789
申请日：2002-10-18
发明人： LIVESEY STEPHEN A , MCQUILLAN DAVID J , BENIKER HERBERT DANIEL , BOERBOOM LAWRENCE E , HAGGARD WARREN O
IPC分类号： A61L27/00 , A61K35/12 , A61K35/22 , A61K35/32 , A61K35/34 , A61K35/36 , A61K35/38 , A61K35/44 , A61K35/55 , A61K45/00 , A61P1/00 , A61P9/00 , A61P9/04 , A61P13/02 , A61P13/10 , A61P17/00 , A61P19/02 , A61P19/08 , A61P21/00 , A61P25/00 , A61P43/00 , A01N63/00 , A61K48/00
CPC分类号： A61K35/32 , A61K35/36 , A61K38/00 , A61L27/3608 , A61L27/362 , A61L27/3804 , A61L27/54 , A61L2430/02
摘要： The invention provides methods of repairing damage to, or defects in, mammalian tissues or organs. In these methods, a particulate or non-particulate acellular matrix made from a tissue or organ other than the tissue or organ being repaired is placed in or on the organ or tissue that is being repaired.
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45.发明公开VERFAHREN ZUR GEWINNUNG EINES AN NICHT-KONJUGIERTEN LIPOPHILEN VERBINDUNGEN ABGEREICHERTEN NAT RLICHEN GEMISCHES KONJUGIERTER EQUINER STROGENE 有权PROCEDURE用于获得TO非共轭的亲脂性CONNECTIONS耗尽NAT MIXTURE自然科学共轭马雌激素
公开(公告)号：EP1553959A1
公开(公告)日：2005-07-20
申请号：EP03808742.5
申请日：2003-10-08
CPC分类号： A61K31/56
摘要： The invention relates to a method for extracting an extract, which contains the natural mixture of conjugated equine estrogens, by the liquid-liquid extraction of the mixture of conjugated equine estrogens. The extracted mixture is depleted of non-conjugated lipophilic compounds from the group consisting of non-conjugated flavonoids, non-conjugated isoflavonoids, non-conjugated norisoprenoids, non-conjugated steroids, particularly androstane and pregnane steroids, and comparable non-conjugated compounds.
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公开(公告)号：EP1278530B1
公开(公告)日：2005-06-15
申请号：EP01943290.5
申请日：2001-04-26
申请人： Breivogel, Boris
发明人： BREIVOGEL, Boris , KIEF, Horst
CPC分类号： A61K35/14 , A61K33/40 , A61K35/22 , A61K2300/00
摘要： New methods for the chemical modification of mammal urine and mammal blood are disclosed for the treatment of diseases.
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47.发明公开Pharmaceutical composition inducing cancer cell differentiation and their use for treatment and prevention of cancer 审中-公开一种药物组合物诱导肿瘤细胞的分化和它们用于治疗和预防癌症中的用途
公开(公告)号：EP1419779A1
公开(公告)日：2004-05-19
申请号：EP02025733.3
申请日：2002-11-15
申请人： Bio Grand Co., Ltd.
发明人： Liau, Ming-Cheng
CPC分类号： A61K31/192 , A61K31/525 , A61K35/22 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition for the treatment and prevention of cancer and the preparation method thereof, especially to a cell differentiation agent named CDA-II which is prepared by reverse phase chromatography of fresh human urine. The pharmaceutical composition is effective for the treatment and prevention of cancer. The active components in CDA-II contain differentiation inducers, differentiation helper inducers and an anticachexia agent, which act cooperatively to achieve the best therapeutic effect.
摘要翻译： 本发明涉及用于治疗和预防癌症和它们的制备方法，爱的药物组合物尤其是命名为CDA-II全部是由新鲜人尿的反相色谱制备的细胞分化剂。 该药物组合物是有效的用于治疗和预防癌症。 在CDA II的活性成分含有分化诱导，分化诱导帮手和抗恶剂，作用协同，以达到最佳的治疗效果。
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公开(公告)号：EP0923381B1
公开(公告)日：2004-04-14
申请号：EP96930139.9
申请日：1996-08-30
摘要： Disclosed is a method to obtain an extract containing a natural mixture of conjugated oestrogens from mare's urine by solid-phase extraction of the mixture of conjugated oestrogens from pregnant mare's urine on non-ionic semipolar polymer adsorbing resins.
摘要翻译： 本发明公开了一种通过固相提取来自怀孕母马尿的结合雌激素在非离子半极性聚合物吸附树脂上的混合物而获得含有来自马尿的结合雌激素的天然混合物的提取物的方法。
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公开(公告)号：EP1278530A2
公开(公告)日：2003-01-29
申请号：EP01943290.5
申请日：2001-04-26
申请人： Breivogel, Boris
发明人： BREIVOGEL, Boris , KIEF, Horst
CPC分类号： A61K35/14 , A61K33/40 , A61K35/22 , A61K2300/00
摘要： New methods for the chemical modification of mammal urine and mammal blood are disclosed for the treatment of diseases.
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公开(公告)号：EP0356836B1
公开(公告)日：1994-05-11
申请号：EP89115272.0
申请日：1989-08-18
申请人： KOWA COMPANY, LTD.
CPC分类号： C07K14/7455 , A61K38/00 , Y10S530/834
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