PROCESS FOR THE PREPARATION OF CEPHEM COMPOUNDS
    57.
    发明公开
    PROCESS FOR THE PREPARATION OF CEPHEM COMPOUNDS 有权
    VERFAHREN ZUR HERSTELLUNG VON CEPHEM-VERBINDUNGEN

    公开(公告)号:EP1209160A4

    公开(公告)日:2002-10-30

    申请号:EP00956785

    申请日:2000-08-30

    申请人: OTSUKA KAGAKU KK

    CPC分类号: C07D501/00 Y02P20/55

    摘要: A process for the preparation of 3-alkenylcephem or 3-norcephem compounds represented by general formula (3), characterized by treating a 3-cephem compound of general formula (1) in a solvent with an alkenyl halide of general formula (2), a nickel catalyst, a metal having a standard redox potential of -0.3 (V/SCE) or below , and a compound of a metal having a standard redox potential higher than that of the above metal. Formula (1) (wherein R1 is hydrogen or the like; R2 is hydrogen or the like; R3 is hydrogen or a carboxyl-protecting group; and X is halogeno or the like). (Formula 2) R4-Y wherein R4 is optionally substituted 1-alkenyl; and Y is halogeno. Formula (3) (wherein R?1, R2, and R3¿ are each as defined above; and R5 is hydrogen or optionally substituted 1-alkenyl).

    摘要翻译: 1.一种制备式(3)的3-链烯基头孢烯化合物或3-去头孢烯化合物的方法,其特征在于式(2)的烯基卤,镍催化剂,高达-0.3(V / SCE) 在标准氧化还原电位和具有比金属更高的标准氧化还原电位的金属的化合物在溶剂中作用于式(1)的3-头孢烯化合物,其中R 1是 氢原子等,R 2为氢原子等,R 3为氢原子或羧酸保护基,X为卤素原子等,R 4 -Y其中R 4是具有或不具有取代基的1-烯基,Y是卤素原子其中R 1,R 2和R 3如上所定义,R 5是 氢原子或具有或不具有取代基的1-烯基。

    PRINTING SHEETS
    60.
    发明公开
    PRINTING SHEETS 失效
    DRUCKBLÄTER

    公开(公告)号:EP1008618A4

    公开(公告)日:2000-10-25

    申请号:EP97950383

    申请日:1997-12-25

    申请人: OTSUKA KAGAKU KK

    摘要: A printing sheet shaped from a resin containing 5 to 80 wt. % of a fibrous electrically conductive filler less than 100 OMEGA .cm in volume resistivity, having 3 to 50 mu m in average fiber length, 0.01 to 5 mu m in average fiber diameter and 3 to 100 in aspect ratio and having a surface coated with an electrically conductive layer containing at least a tin oxide and an antimony oxide, or a printing sheet comprising a film substrate and a covering layer formed on at least one surface of the substrate and comprising a resin containing the above conductive filler.

    摘要翻译: 一种印刷用薄片,其特征在于,将含有5〜80重量%的纤维状导电性填料的树脂以体积电阻率小于100Ω·cm,平均纤维长度为3〜50μm,平均纤维直径 0.01至5微米,取向比为3至100,所述填料的表面涂覆有至少包含氧化锡和氧化锑的导电层; 以及另一印刷片,其包含由上述含导电性填料的树脂形成并设置在膜基材的至少一面上的涂层。