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136 条记录 (耗时 0.077 秒)

    Isomerases, nucleic acids encoding them and methods for making and using them
    53.
    发明公开
    Isomerases, nucleic acids encoding them and methods for making and using them 审中-公开
    异构酶，编码它们的核酸，以及制备方法及其用途

    公开(公告)号：EP2706122A2

    公开(公告)日：2014-03-12

    申请号：EP13195575.9

    申请日：2008-12-22

    申请人： Verenium Corporation

    发明人： Weiner, David ,  Burke, Ellen ,  Bueno, Analia ,  Cuenca, Joslin ,  De Souza, Mervyn L. ,  Kollmann, Sherry ,  Luginbuhl, Peter

    IPC分类号： C12Q1/533 ,  C12N9/90 ,  C12N15/61 ,  A61K38/52 ,  A23K1/165 ,  A23G4/12

    CPC分类号： C12N9/90 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/10 ,  A23G3/366 ,  A23G4/123 ,  A23G4/14 ,  A23K20/189 ,  A23L29/06 ,  A23V2002/00 ,  A61K38/00 ,  A61K38/52 ,  C12Q1/533 ,  C12Y501/00 ,  C12Y501/01

    摘要： This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having isomerase activity, e.g., racemase activity, e.g., amino acid racemase activity, alanine racemase activity, and/or epimerase activity, and/or catalyze the rearrangement of atoms within a molecule, catalyze the conversion of one isomer into another, catalyze the conversion of an optically active substrate into a raceme, which is optically inactive, catalyze the interconversion of substrate enantiomers, catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry, catalyze the stereochemical inversion of the configuration around an asymmetric carbon atom in a substrate having more than one asymmetric center, and/or catalyze the racemization of amino acids. Thus, the invention provides enzymes, compositions, methods for production of pharmaceutical compositions, pharmaceutical intermediates, antibiotics, sweeteners, peptide enzymes, peptide hormones, fuel and fuel additive compositions, foods and food additives, beverage and beverage additives, feeds and feed additives, drugs and drug additives, dietary supplements, textiles, wood, paper, pulp, and detergents comprising the polypeptides or polynucleotides in accordance with the invention.

    摘要翻译： 本发明涉及基因的反弹于酶，多核苷酸编码的酶，利用搜索多核苷酸和多肽，更具体的涉及具有异构酶活性的酶，例如，消旋酶活性，例如，氨基酸消旋酶活性，丙氨酸消旋酶活性，和/或差向异构酶活性， 和/或催化的原子的重新排列的分子内，催化一种异构体转化为另一种，催化的光学活性底物转化成一总状花序，其全部在光学上是不活动的，催化底物的相互转换对映异构体围绕催化的立体化学反转 在仅具有一个不对称中心基板的不对称碳原子，围绕催化的配置的立体化学反转在不对称碳原子中具有多于一个不对称中心的基底，和/或催化的氨基酸外消旋化。 因此，本发明提供的酶，组合物，方法用于制备药物组合物，医药中间体，抗生素，甜味剂，肽酶，肽类激素，燃料，燃料添加剂组合物，食品和食品添加剂，饮料和饮料添加剂，饲料和饲料添加剂， 药物和药物添加剂，膳食补充剂，纺织品，木材，纸，纸浆，和洗涤剂包括以本发明在雅舞蹈的多肽或多核苷酸。

    Cellucloytic enzymes, nucleic acids encoding them and methods for making and using them
    59.
    发明公开
    Cellucloytic enzymes, nucleic acids encoding them and methods for making and using them 有权
    Cellucloytic酶，编码它们的核酸以及制造和使用它们的方法

    公开(公告)号：EP2444489A1

    公开(公告)日：2012-04-25

    申请号：EP11007475.4

    申请日：2006-12-08

    申请人： Verenium Corporation

    发明人： Gray, Kevin A. ,  Zhao, Lishan ,  Cayouette, Michelle H.

    IPC分类号： C12N9/42

    CPC分类号： C12N9/2437 ,  C12N9/2402 ,  C12N9/2405 ,  C12N9/248 ,  C12Y302/01004 ,  C12Y302/01006 ,  C12Y302/01008 ,  C12Y302/01021 ,  C12Y302/01023 ,  C12Y302/01039 ,  C12Y302/01055 ,  C12Y302/01091 ,  Y02E50/16 ,  Y02E50/17 ,  Y10T428/249921

    摘要： The invention provides polypeptides having any cellulolytic activity, e.g., a cellulase activity, a endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a β-xylosidase, an arabinofuranosidase, and/or an oligomerase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, β-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides having an oligomerase activity, e.g., enzymes that convert recalcitrant soluble oligomers to fermentable sugars in the saccharification of biomass. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.

    摘要翻译： 本发明提供了具有任何纤维素分解活性的多肽，例如纤维素酶活性，内切葡聚糖酶，纤维二糖水解酶，β-葡糖苷酶，木聚糖酶，甘露聚糖酶，β-木糖苷酶，阿拉伯呋喃糖苷酶和/或寡聚体酶活性，编码这些的多核苷酸 多肽，以及制备和使用这些多核苷酸和多肽的方法。 一方面，本发明涉及具有任何纤维素分解活性的多肽，例如纤维素酶活性，例如内切葡聚糖酶，纤维二糖水解酶，β-葡糖苷酶，木聚糖酶，甘露聚糖酶，β-木糖苷酶，阿拉伯呋喃糖苷酶和/或寡聚体酶活性，包括热稳定的和 耐热活性和编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。 在一个方面，本发明提供了具有寡聚体酶活性的多肽，例如在生物质糖化中将难溶性可溶性寡聚物转化成可发酵糖的酶。 本发明的多肽可以用于各种制药，农业，食品和饲料加工和工业环境中。 本发明还提供包含含有至少一种本发明酶的酶混合物的组合物或产品。

    Cellucloytic enzymes, nucleic acids encoding them and methods for making and using them
    60.
    发明公开
    Cellucloytic enzymes, nucleic acids encoding them and methods for making and using them 有权

    公开(公告)号：EP2444488A1

    公开(公告)日：2012-04-25

    申请号：EP11007474.7

    申请日：2006-12-08

    申请人： Verenium Corporation

    发明人： Gray, Kevin A. ,  Zhao, Lishan ,  Cayouette, Michelle H.

    IPC分类号： C12N9/42

    CPC分类号： C12N9/2437 ,  C12N9/2402 ,  C12N9/2405 ,  C12N9/248 ,  C12Y302/01004 ,  C12Y302/01006 ,  C12Y302/01008 ,  C12Y302/01021 ,  C12Y302/01023 ,  C12Y302/01039 ,  C12Y302/01055 ,  C12Y302/01091 ,  Y02E50/16 ,  Y02E50/17 ,  Y10T428/249921

    摘要： The invention provides polypeptides having any cellulolytic activity, e.g., a cellulase activity, a endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a β-xylosidase, an arabinofuranosidase, and/or an oligomerase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, β-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides having an oligomerase activity, e.g., enzymes that convert recalcitrant soluble oligomers to fermentable sugars in the saccharification of biomass. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.