利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

345 条记录 (耗时 0.032 秒)

    METHOD FOR PRODUCING OPTICALLY-ACTIVE -SUBSTITUTED- -AMINO ACID
    53.
    发明公开
    METHOD FOR PRODUCING OPTICALLY-ACTIVE -SUBSTITUTED- -AMINO ACID 审中-公开
    VERFAHREN ZUR HERSTELLUNG EINER OPTISCH AKTIVEN SUBSTITUIERTENAMINOSÄURE

    公开(公告)号：EP2796562A1

    公开(公告)日：2014-10-29

    申请号：EP12859103.9

    申请日：2012-12-06

    申请人： Sumitomo Chemical Co., Ltd

    发明人： AKIYAMA, Toshihiko ,  HIRATA, Norihiko

    IPC分类号： C12P41/00 ,  C12P13/04 ,  C12N9/18

    CPC分类号： C12P13/04 ,  C12P41/005

    摘要： The invention provides a method for producing an optically active α,-substituted-β-amino acid represented by formula (2), the method comprising a step in which an optical isomer mixture of an α-substituted-β-amino acid ester represented by formula (1) is subjected to asymmetric hydrolysis by using an enzyme and such capable of asymmetrically hydrolyzing the ester site of said optical isomer mixture.

    (In the formulae, R 1 represents an acyl group, a carboxyl group, or a carboxamide group; R 2 represents an alkyl group, an aryl group, an aralkyl group, a cyclic ether group, or the like; R 3 represents an optionally-substituted C 1 to C 20 hydrocarbon group; R 4 represents an alkyl group; X represents an oxygen atom or a sulfur atom; and * represents the asymmetric center.)

    摘要翻译： 本发明提供一种制备由式（2）表示的光学活性的±， - 取代-2-氨基酸的方法，该方法包括以下步骤：将由 - 取代的2-氨基酸酯的光学异构体混合物 式（1）通过使用酶进行不对称水解，并且能够不对称地水解所述光学异构体混合物的酯位点。 （式中，R 1表示酰基，羧基或羧酰胺基; R 2表示烷基，芳基，芳烷基，环状醚基等）; R 3表示可以具有 取代的C 1至C 20烃基; R 4表示烷基; X表示氧原子或硫原子; *表示不对称中心。

    Table assembly
    55.
    发明公开
    Table assembly 有权
    表组件

    公开(公告)号：EP2752129A1

    公开(公告)日：2014-07-09

    申请号：EP14162832.1

    申请日：2011-06-02

    申请人： Steelcase Inc.

    发明人： Martin, Kirt ,  Eberlein, David C.

    IPC分类号： A47B21/06

    CPC分类号： A47B3/06 ,  A47B13/003 ,  A47B13/02 ,  A47B13/08 ,  A47B17/04 ,  A47B21/06 ,  A47B2021/062 ,  A47B2083/025

    摘要： A table assembly comprising at least a first leg member that forms a leg opening and a first support surface and a rigid elongated channel member that forms a channel that extends between first and second ends, at least the first end forming a wire passing opening suitable to pass wires into and out of the channel, the first end supportable by the first support surface in at least first and second different locations, wherein, when the channel is supported by the support surface at either of the first and second different positions, the wire passing opening is aligned with the leg opening so that wires can pass through the leg opening and into the channel.

    摘要翻译： 一种桌子组件，其包括形成腿部开口和第一支撑表面的至少第一腿部构件和形成在第一端部与第二端部之间延伸的通道的刚性细长通道构件，至少第一端部形成适于 使得导线进入和离开所述通道，所述第一端可由所述第一支撑表面在至少第一和第二不同位置处支撑，其中，当所述通道在所述第一和第二不同位置中的任一个处由所述支撑表面支撑时，所述导线 通过开口与腿部开口对准，使得导线可以穿过腿部开口并进入通道。

    3-(BIARYLOXY) PROPIONIC ACID DERIVATIVE
    60.
    发明公开
    3-(BIARYLOXY) PROPIONIC ACID DERIVATIVE 有权
    3-（双环己基）丙酸衍生物

    公开(公告)号：EP2471792A1

    公开(公告)日：2012-07-04

    申请号：EP10811982.7

    申请日：2010-08-27

    申请人： Daiichi Sankyo Company, Limited

    发明人： NISHI, Tatsuya ,  NAKAMOTO, Yumi ,  OCHIAI, Yuichi ,  KITAZAWA, Ryoko ,  HASEGAWA, Masashi ,  SUSAKI, Hiroshi

    IPC分类号： C07D471/04 ,  A61K31/4375 ,  A61K31/4545 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/542 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/10 ,  C07D401/04 ,  C07D413/04 ,  C07D498/04 ,  C07D513/04

    CPC分类号： C07D413/04 ,  C07D401/04 ,  C07D471/04 ,  C07D498/04 ,  C07D513/04

    摘要： A compound of the general formula (I):

    [wherein, R 1 represents a halogen atom, or the like, R 2 represents a hydrogen atom, or the like, R 3 and R 4 , each independently, represent a hydrogen atom, a C 1-4 alkyl group, or the like, R 5 represents a hydrogen atom, a halogen atom, or the like, R 6 represents a hydrogen atom, a halogen atom, or the like, R 7 and R 8 , each independently, represent a hydrogen atom, a halogen atom, or the like, R 9 and R 10 , each independently, represent a hydrogen atom, a C 1-4 alkyl group, R 11 and R 12 , each independently, represent a hydrogen atom, a C 1-4 alkyl group, or the like, X represents an oxygen atom, a group -CH 2 -, or the like, Y represents a nitrogen atom, a group =CH-, or the like, and Z represents a nitrogen atom, or the like] or a pharmacologically acceptable salt thereof, which has an excellent suppressive action on platelet aggregation, and is useful for prevention and/or treatment of thromboembolism.

    摘要翻译： 通式（I）的化合物：[其中，R 1表示卤素原子等，R 2表示氢原子等，R 3和R 4各自独立地表示氢原子，C 1-4烷基 基团等，R 5表示氢原子，卤素原子等，R 6表示氢原子，卤素原子等，R 7和R 8各自独立地表示氢原子，卤素原子等。 R 9和R 10各自独立地表示氢原子，C 1-4烷基，R 11和R 12各自独立地表示氢原子，C 1-4烷基等，X表示氧 原子，基团-CH2-等，Y表示氮原子，基团= CH-等，并且Z表示氮原子等]或其药理学上可接受的盐，其具有优异的 对血小板凝集的抑制作用，可用于预防和/或治疗血栓栓塞症。