Process for producing aminophenyl-beta-hydroxyethylsulfone
    63.
    发明公开
    Process for producing aminophenyl-beta-hydroxyethylsulfone 失效
    生产氨基苯丙氨酸羟基乙氧基化合物的方法

    公开(公告)号:EP0092909A3

    公开(公告)日:1985-04-17

    申请号:EP83301683

    申请日:1983-03-25

    CPC分类号: C07C323/00 C07C317/00

    摘要: A process for producing aminophenyl-β-hydroxyethylsulfone of the formula (I),
    which comprises steps:
    (1) condensing nitrohalobenzene with mercaptoethanol in the presence of an alkali hydroxide and at least one reaction medium selected from N-alkyl-substituted amides and sulfoxides to produce mono-nitrophenyl-β-hydroxyethylsulfide of the formula (II):
    (2) oxidizing the mononitrophenyl-β-hydroxyethylsulfide (II) to produce mononitrophenyl-β-hydroxyethylsulfone of the formula (III):
    and (3) reducing the mononitrophenyl-β-hydroxyethylsulfone to produce the aminophenyl-β-hydroxyethylsulfone of the formula (I). This compound is useful as an intermediate for aminophenyl-β-sulfatoethylsulfone represented by the following formula:
    which is an important intermeidate for vinyl sulfone type reactive dyes largely used for dyeing cellulose fiber materials.