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433 条记录 (耗时 0.015 秒)

    Method for storage stabilization of compounds with oxetane rings
    71.
    发明公开
    Method for storage stabilization of compounds with oxetane rings 有权
    一种用于与氧杂环丁烷环的化合物的储存稳定化方法

    公开(公告)号：EP1013648A3

    公开(公告)日：2000-10-11

    申请号：EP99125436.8

    申请日：1999-12-20

    申请人： Toagosei Co., Ltd.

    发明人： Ito, Naokazu ,  Sasaki, Hiroshi ,  Kuriyama, Akira

    IPC分类号： C07D305/06

    CPC分类号： C07D305/06

    摘要： Storage stabilization of compounds with an oxetane ring or oxetane rings, which are useful as ring opening polymerizable monomers, is improved by addition of basic compounds thereto. The basic compound is preferably an alkali metal hydroxide or an amine. The compound with an oxetane compound preferably has a substituent at the 3- or 2-position thereof. Addition amount of the basic compound is preferably 0.1 to 1,000 ppm by weight, more preferably 1 to 1,000 ppm by weight per the compound with an oxetane.

    Method for storage stabilization of compounds with oxetane rings
    73.
    发明公开
    Method for storage stabilization of compounds with oxetane rings 有权
    具有氧杂环丁烷环的化合物的储存稳定化方法

    公开(公告)号：EP1013648A2

    公开(公告)日：2000-06-28

    申请号：EP99125436.8

    申请日：1999-12-20

    申请人： Toagosei Co., Ltd.

    发明人： Ito, Naokazu ,  Sasaki, Hiroshi ,  Kuriyama, Akira

    IPC分类号： C07D305/06

    CPC分类号： C07D305/06

    摘要： Storage stabilization of compounds with an oxetane ring or oxetane rings, which are useful as ring opening polymerizable monomers, is improved by addition of basic compounds thereto. The basic compound is preferably an alkali metal hydroxide or an amine. The compound with an oxetane compound preferably has a substituent at the 3- or 2-position thereof. Addition amount of the basic compound is preferably 0.1 to 1,000 ppm by weight, more preferably 1 to 1,000 ppm by weight per the compound with an oxetane.

    摘要翻译： 具有氧杂环丁烷环或氧杂环丁烷环的化合物的贮存稳定化通过向其中加入碱性化合物而得到改进，所述氧杂环丁烷环或氧杂环丁烷环可用作开环可聚合单体。 碱性化合物优选为碱金属氢氧化物或胺。 具有氧杂环丁烷化合物的化合物优选在其3位或2位具有取代基。 碱性化合物的添加量相对于具有氧杂环丁烷的化合物优选为0.1〜1000重量ppm，更优选为1〜1000重量ppm。

    Process for producing pressure-sensitive adhesive sheet
    74.
    发明公开
    Process for producing pressure-sensitive adhesive sheet 有权
    韦尔法罕zur Herstellung eines drucksensitiven Klebmittelfilmes

    公开(公告)号：EP0978551A1

    公开(公告)日：2000-02-09

    申请号：EP99115286.9

    申请日：1999-08-02

    申请人： TOAGOSEI CO., LTD.

    发明人： Koketsu, Akemi, c/o Toagosei Co., Ltd. ,  Tanaka, Minoru, c/o Toagosei Co., Ltd. ,  Iesako, Hiroshi, c/o Toagosei Co., Ltd.

    IPC分类号： C09J7/02

    CPC分类号： C09J133/062 ,  C08L33/08 ,  C09J7/22 ,  C09J7/38 ,  C09J7/385 ,  C09J2201/606

    摘要： A process for producing a pressure-sensitive adhesive sheet using an aqueous resin emulsion is disclosed. The aqueous resin emulsion is an aqueous resin emulsion that dispersed particles have a weight average particle diameter of 0.3 µm or smaller and a ratio of the weight average particle diameter thereof to an arithmetic average particle diameter thereof [(weight average particle diameter)/(arithmetic average particle diameter)] is 1.0 to 1.5. The resin contained in the aqueous resin emulsion preferably comprises an alkyl (meth)acrylate monomer unit (a) having 4 to 12 carbon atoms in the alkyl moiety, an α,β-ethylenically unsaturated carboxylic acid monomer unit (b), and a radically polymerizable monomer unit (c) having a cyclic structure, other than the monomer units (a) and (b), the proportions of the monomer unit (a), the monomer unit (b), and the monomer unit (c) being 45 to 97% by weight, 0.1 to 10% by weight, and 2.9 to 30% by weight, respectively, with the total amount of those units being 100% by weight. The aqueous resin emulsion preferably contains a nonionic surfactant. The pressure-sensitive adhesive sheet obtained by the process has a property such that the pressure-sensitive adhesive layer thereof is less apt to blush even upon contact with water by immersion in water, moisture absorption, etc.

    摘要翻译： 公开了一种使用水性树脂乳液制备压敏粘合片的方法。 水性树脂乳液是分散粒子的重量平均粒径为0.3μm以下，其重均粒径与其算术平均粒径的比例Ä（重均粒径）/（ 算术平均粒径）Ü为1.0〜1.5。 包含在水性树脂乳液中的树脂优选包括在烷基部分中具有4至12个碳原子的（甲基）丙烯酸烷基酯单体单元（a），α，β-烯键式不饱和羧酸单体单元（b），和 单体单元（a）和（b）以外的具有环状结构的聚合性单体单元（c）的单体单元（a），单体单元（b）和单体单元（c）的比例为45 至97重量％，0.1至10重量％和2.9至30重量％，其中这些单元的总量为100重量％。 水性树脂乳液优选含有非离子表面活性剂。 通过该方法获得的压敏粘合片具有这样的性质，使得即使在与水接触的情况下，其粘合剂层也易于沾湿，浸渍在水中，吸湿等。

    HEAT-SENSITIVE AND PRESSURE-SENSITIVE ADHESIVE SHEET
    75.
    发明公开
    HEAT-SENSITIVE AND PRESSURE-SENSITIVE ADHESIVE SHEET 失效
    WÄRMEEMPFLINDLICHEUND DRUCKEMPFINDLICHE KLEBESCHICHT

    公开(公告)号：EP0913443A1

    公开(公告)日：1999-05-06

    申请号：EP97930842.6

    申请日：1997-07-18

    申请人： TOAGOSEI CO., LTD.

    发明人： KAMIYA, Daisuke, Toagosei Co., Ltd. ,  MAEDA, Keiji, Toagosei Co., Ltd. ,  OTA, Hiroyuki, Toagosei Co., Ltd.

    IPC分类号： C09J7/02

    CPC分类号： C09J133/064 ,  C08L33/064 ,  C08L2666/04 ,  C09J7/38 ,  C09J7/385 ,  C09J133/066 ,  C09J2201/122 ,  C09J2201/606 ,  C09J2201/61 ,  Y10T428/2826 ,  Y10T428/2891

    摘要： A heat-sensitive adhesive sheet comprising a substrate having formed thereon an adhesive layer comprising a polymer composition (C) which comprises the following aqueous emulsion (A) and copolymer (B), wherein an adhesive force determined by the 180° peeling test method as specified in JIS Z 0237 at a temperature of 25°C is 10 g/25 mm or less:

    Aqueous emulsion (A): An aqueous emulsion containing an alkyl (meth)acrylate-based polymer (a) having a glass transition temperature of -10°C or below, which is obtained by emulsion-polymerizing radically polymerizable monomers containing as the main component an alkyl (meth)acrylate; and
    Copolymer (B): A water-soluble or water-dispersible copolymer (B) having a glass transition temperature of 20°C or above, which is a copolymer obtained by copolymerizing an α,β-ethylenically unsaturated carboxylic acid with other radically polymerizable monomers, wherein a part or the entire amount of carboxyl groups in the copolymer is neutralized with a base having a boiling point of 110°C or below.

    摘要翻译： 1.一种热敏粘合片，其特征在于，具有在其上形成有包含下述水性乳液（A）和共聚物（B））的聚合物组合物（C）的粘合剂层的基材，其中，通过180°剥离试验方法测定的粘合力为 JIS Z 0237在25℃下规定为10g / 25mm以下：水性乳液（A）：含有玻璃化转变温度为（ - ）的（甲基）丙烯酸烷基酯系聚合物（a）的水乳液， 通过使含有作为主要成分的（甲基）丙烯酸烷基酯的自由基聚合性单体进行乳液聚合而获得的10℃以下。 和共聚物（B）：玻璃化转变温度为20℃以上的水溶性或水分散性共聚物（B），其是通过使α，β-烯键式不饱和羧酸与其他可自由基聚合的共聚物 单体，其中共聚物中的部分或全部羧基用沸点为110℃或更低的碱中和。

    ANTISENSE NUCLEIC ACID COMPOUND
    77.
    发明公开
    ANTISENSE NUCLEIC ACID COMPOUND 失效
    反义核酸化合物

    公开(公告)号：EP0769552A1

    公开(公告)日：1997-04-23

    申请号：EP95921109.5

    申请日：1995-06-07

    申请人： TOAGOSEI CO., LTD.

    发明人： UCHIDA, Kiyoshi ,  UCHIDA, Takayoshi ,  TANAKA, Youichi ,  MATSUDA, Yoko ,  KONDO, Shinishi

    IPC分类号： C12N15/11 ,  A61K48/00 ,  G01N33/50

    CPC分类号： C12N15/1136 ,  A61K38/00 ,  C12N2310/315 ,  G01N33/564 ,  G01N33/57496 ,  G01N33/74 ,  G01N2333/475

    摘要： The present invention relates to an antisense nucleic acid compound which has a nucleotide sequence complementary to at least 8 contiguous nucleotides in the nucleotide sequence of a gene coding for a vascular endothelial growth factor and which inhibits the expression of the vascular endothelial growth factor, as well as to a therapeutic or diagnostic agent for cancers, rheumatoid arthritis, diabetes etc., comprising said antisense nucleic acid as active ingredient. Further, the present invention relates to a method of preventing the expression of the vascular endothelial growth factor, comprising use of an antisense nucleic acid compound which has a nucleotide sequence complementary to at least 8 contiguous nucleotides in the nucleotide sequence of a gene coding for a vascular endothelial growth factor and which inhibits the expression of the vascular endothelial growth factor.

    摘要翻译： 本发明涉及一种反义核酸化合物，其具有与编码血管内皮生长因子的基因的核苷酸序列中的至少8个连续核苷酸互补的核苷酸序列，并且还抑制血管内皮生长因子的表达 涉及包含所述反义核酸作为活性成分的癌症，类风湿性关节炎，糖尿病等的治疗剂或诊断剂。 此外，本发明涉及一种防止血管内皮生长因子表达的方法，该方法包括使用反义核酸化合物，该化合物的核苷酸序列与编码一种基因的核苷酸序列中的至少8个连续核苷酸互补 血管内皮生长因子并抑制血管内皮生长因子的表达。

    MULTI-LAYER SHEET AND METHOD FOR PRODUCING SAME
    80.
    发明公开
    MULTI-LAYER SHEET AND METHOD FOR PRODUCING SAME 审中-公开

    公开(公告)号：EP4332188A1

    公开(公告)日：2024-03-06

    申请号：EP22795851.9

    申请日：2022-04-27

    申请人： Toagosei Co., Ltd.

    发明人： IMAHORI Makoto ,  MIYAMURA Kentaro ,  IWATSUKI Keigo ,  TSUDA Takashi

    IPC分类号： C09J7/35 ,  B32B27/00 ,  C09J123/26 ,  C09J151/06 ,  C09J201/00

    摘要： The problem to be solved by the present invention is to provide a multilayer sheet including an adhesive layer that includes an acid-modified polyolefin and a substrate layer that includes a polyphenylene ether, and having high peel strength between the adhesive layer and the substrate layer. The multilayer sheet of the present invention includes: a substrate layer (A) that includes 40 to 99.9% by mass of a polyphenylene ether (a1), 0 to 59.9% by mass of a polystyrene (a2), and an amino group-containing polymer (a3); and an adhesive layer (B) that includes an acid-modified polyolefin.