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    Implantable prosthetic device
    79.
    发明授权
    Implantable prosthetic device 有权
    Implantierbare Prothesevorrichtung

    公开(公告)号：EP2399549B1

    公开(公告)日：2014-03-19

    申请号：EP11005557.1

    申请日：2002-10-11

    申请人： Edwards Lifesciences PVT, Inc.

    发明人： Spenser, Benjamin ,  Benichou, Netanel ,  Bash, Assaf ,  Zakai, Avraham

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/2403 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2421 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2463 ,  A61F2/82 ,  A61F2002/9522 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0069 ,  A61F2250/001 ,  A61F2250/0098

    摘要： A prosthetic device for replacing a deficient native aortic valve is disclosed, comprising: - a collapsible and expandable support stent formed of a shape memory alloy, - the support stent comprising a proximal stent portion (310) configured to expand to a first diameter and - an distal stent portion (320) configured to expand to a second diameter, the first diameter being smaller than the second diameter for preventing deformation of the mitral valve by over expansion and for providing a difference between the support stent and the openings of the coronary arteries; and - a collapsible and expandable valve assembly formed of natural tissue, whereby the valve assembly is attached to the support stent circumferentially along an inlet and sutured to the support stent along commissures for supporting the valve leaflets; wherein the first diameter of the support stent is sized for engagement with leaflets of the native aortic valve and the second diameter of the support stent is sized for engagement with the inner wall of the ascending aorta and wherein the stent is sized to avoid a contact with the inner wall of a left ventricle when implanted.

    摘要翻译： 公开了一种用于替代缺乏的天然主动脉瓣的假体装置，包括： - 由形状记忆合金形成的可折叠和可扩张的支撑支架，所述支撑支架包括构造成扩张到第一直径的近端支架部分（310） 构造成扩张到第二直径的远端支架部分（320），所述第一直径小于所述第二直径，用于防止二尖瓣由于过度膨胀而变形，并且用于在支撑支架和冠状动脉的开口之间提供差异 ; 以及 - 由天然组织形成的可折叠且可膨胀的阀组件，由此所述阀组件沿着入口周向地附接到所述支撑支架，并且沿着用于支撑所述瓣叶的合并缝合到所述支撑支架; 其中所述支撑支架的所述第一直径的尺寸设定成与所述天然主动脉瓣的小叶接合，并且所述支撑支架的所述第二直径的尺寸被设计成与所述升主动脉的内壁接合，并且其中所述支架的尺寸设定成避免与 植入后左心室的内壁。