摘要:
A method of immunologically analyzing a plasmin degradation product of stabilized fibrin characterized in that a) a monoclonal antibody that does not react with stabilized fibrin, fibrinogen or a plasmin degradation product of fibrinogen but reacts with a neoantigen of D domain generated by plasmin degradation of stabilized fibrin and (b) a monoclonal antibody that specifically reacts with a plasmin degradation product of stabilized fibrin by recognizing a site different from that for the monoclonal antibody (a) are used in combination, one of the monoclonal antibodies (a) and (b) is conjugated to a magnetic particle and the other monoclonal antibody is labeled with an enzyme, and a chemiluminescent substrate is used as a substrate for the enzyme is disclosed.
摘要:
A measuring device (100) comprising a cofocal-point optical microscope (110), an excitation light source unit (130) that emits an excitation light for generating fluorescence from a fluorescent material, and a light receiving unit (140). The cofocal-point optical microscope (110) has an excitation light input port (112) for capturing an excitation light from the excitation light source unit (130), and an output port (113) for outputting fluorescence generated by an excitation light. The light receiving unit (140) has an input unit (141) for capturing a signal light including fluoresence from the microscope (110). The input unit (141) of the light receiving unit (140) is optically connected to the output port (113) of the microscope (110) via an optical fiber (153).
摘要:
Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
摘要:
An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.
摘要:
The invention relates to a sample device (1) comprising an array of reaction chambers/wells (3) in a titer plate (2) and a two-dimensional array (10) of thin-film-light sensor elements (12), and each light-sensitive element (12) of the sensor array (10) is disposed directly underneath the individual reaction chamber (3) in order to detect chemical and/or biological reactions.
摘要:
A multi-well plate (1910) having an array of wells, wherein said array corresponds to a 96-well plate or 384-well plate configuration comprising one or more sectors (1910A,1910B,1910C) having wells. Said multi-well plate (1910) having a plurality of electrodes on a top surface and a plurality of contact surfaces on a bottom surface, wherein said plurality of electrodes are electrically connected to said plurality of contact surfaces. A kit for use in the conduct of an ECL assay comprising in one or more containers, the multi-well plate (1910) and at least one ECL label.
摘要:
This invention provides compositions and methods for detection of hematophagous ectoparasitic activity in an enclosure or area. The compositions comprise a reagent or reagents which are reactive against antigens or markers as they appear in the excrement or other ectoparasitic materials. Such markers or antigens may be produced by the ectoparasite itself or may have been introduced into the ectoparasite because of its blood feeding activity. The method of the present invention comprises collecting from the enclosure or area, a sample comprising environmental dust or materials and subjecting the sample to tests for detecting the presence of hematophagous ectoparasitic markers, host markers or both.