公开(公告)号：EP3203295A1

公开(公告)日：2017-08-09

申请号：EP14902940.7

申请日：2014-10-01

申请人： Narishige Lifemed Co., Ltd.

发明人： NOMURA Toru

IPC分类号： G02B21/32 ,  B25J7/00

CPC分类号： B25J7/00 ,  G02B21/32

摘要： A method for positioning a micro-tool (4) comprises: a positioning gauge positioning process (S1) including placing a gauge surface (5d) of a positioning gauge (5) at a needle tip position while the positioning gauge (5) is fixed to a holding part (30), and aligning a mark (5b) provided in the positioning gauge (5) with the optical axis (62a) of an objective lens (62); a positioning gauge focus adjustment process (S2) to focus on the mark (5b) in a state where the positioning gauge (5) has been positioned; and a micro-tool attachment process (S3) including fixing the micro-tool (4) to the holding part (30) after removing the positioning-gauge (5) from the holding part (30).

摘要翻译： 一种用于定位微型工具（4）的方法，包括：定位测量仪定位过程（S1），包括将定位测量仪（5）的测量表面（5d）放置在针尖位置，同时定位测量仪（5）被固定 （30）上，并将设置在定位测量仪（5）中的标记（5b）与物镜（62）的光轴（62a）对齐; 定位仪聚焦调整过程（S2），在定位仪（5）已经定位的状态下聚焦在标记（5b）上; 以及在将所述定位仪（5）从所述保持部（30）移除之后将所述微型工具（4）固定到所述保持部（30）的微型工具安装工序（S3）。

公开(公告)号：EP3079003A1

公开(公告)日：2016-10-12

申请号：EP15163243.7

申请日：2015-04-10

申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

发明人： Huisken, Jan ,  Shah, Gopi

IPC分类号： G02B21/32 ,  G02B21/36

CPC分类号： G02B21/367 ,  F16C32/0406 ,  G01N21/01 ,  G02B21/32

摘要： Method for imaging regions of a sample using a light source and an optical detection means and at least one device for moving the sample in three dimensions, comprising the following method steps:
a) introducing at least one magnetic element into the sample,
b) applying a magnetic field by means of the at least one device for moving the sample in three dimensions, the magnetic field interacting with the at least one magnetic element introduced into the sample,
c) arranging the region of the sample in a radiation region of the light source and in a detection region of the detection means,
d) emitting first light beams from the light source onto the sample,
e) generating second light beams by means of the sample,
f) recording an image of a region of the sample by capturing a proportion, incident on the detection means from the sample, of the second light beams,
g) moving the at least one magnetic element and the sample containing this at least one magnetic element by varying the magnetic field,
h) repeating steps d) to g) until a predeterminable number of images have been recorded.

摘要翻译： 用于使用光源和光学检测装置对样品进行成像的方法和用于三维移动样品的至少一个装置，包括以下方法步骤：a）将至少一个磁性元件引入样品中，b）施加 通过所述至少一个用于在三维上移动所述样本的装置的磁场，与所述至少一个引入到所述样品中的所述至少一个磁性元件相互作用的磁场; c）将所述样品的区域布置在所述光的辐射区域中 源和在检测装置的检测区域中，d）将来自光源的第一光束发射到样品上，e）通过样品产生第二光束，f）通过捕获来记录样品区域的图像 从样品入射到检测装置上的第二光束的比例，g）通过改变磁性元件移动至少一个磁性元件和包含该至少一个磁性元件的样品 字段，h）重复步骤d）至g）直到已经记录了可预定数量的图像。

公开(公告)号：EP2913654A1

公开(公告)日：2015-09-02

申请号：EP13849192.3

申请日：2013-10-04

申请人： Olympus Corporation

发明人： MORIMOTO, Nobuhiko

IPC分类号： G01N1/28 ,  G01N33/48 ,  G02B21/32 ,  G02B21/36

CPC分类号： G01N1/04 ,  B32B41/00 ,  B32B43/006 ,  B32B2310/0831 ,  G01N1/08 ,  G01N1/312 ,  G01N21/6456 ,  G01N2201/025 ,  G02B21/365 ,  Y10T156/1158 ,  Y10T156/1179 ,  Y10T156/19 ,  Y10T156/1917 ,  Y10T156/1983

摘要： The present invention provides a substrate collecting device (1) that includes a stage (3) on which a sheet (11) is placed with a plurality of substrates (2) facing downward, an acquiring section (4) which carries out a predetermined operation on some of the substrates (2), which are disposed at predetermined positions, from above the stage (3) thereby to cause the substrates (2) to come off from the sheet (11) and fall, an observation section (5) and a collecting section (7) disposed below the stage (3), and a moving mechanism (8), which integrally moves the observation section (5) and the collecting section (7) in a horizontal direction. The moving mechanism (8) is capable of positioning the observation section (5) and the collecting section (7) at two positions at which the observation section (5) or the collecting section (7) is positioned substantially vertically below a predetermined position.

摘要翻译： 本发明提供了一种基板收集装置（1），其包括在其上放置有面向下的多个基板（2）的片材（11）的台（3），执行预定操作的获取部分（4） 在从台架（3）的上方配置在预定位置的一些基板（2）上，从而使基板（2）从板材（11）脱落并落下，观察部（5）和 设置在所述台架（3）的下方的收纳部（7）和使所述观察部（5）和所述收集部（7）沿水平方向一体移动的移动机构（8）。 移动机构（8）能够将观察部分（5）和收集部分（7）定位在观察部分（5）或收集部分（7）基本垂直地位于预定位置的两个位置处。

公开(公告)号：EP1630586B1

公开(公告)日：2015-01-07

申请号：EP04745503.5

申请日：2004-06-02

申请人： NIKON CORPORATION

发明人： OKUGAWA, Hisashi, NIKON CORPORATION

IPC分类号： G02B21/30 ,  G02B21/00 ,  G02B21/32 ,  G02B21/26

CPC分类号： G02B21/0088 ,  G02B21/26 ,  G02B21/30 ,  G02B21/32

摘要： A microscope system includes a casing in which an optical element is housed, an airtight specimen chamber, and an environment control unit that controls temperature and humidity in the specimen chamber and also controls temperature inside the casing. An upper plate of the specimen chamber is an open/close lid opened and closed when inserting or removing a biological specimen. The casing becomes sealed by a bottomplate of the specimen chamber as the specimen chamber is set on the casing.

公开(公告)号：EP2806260A1

公开(公告)日：2014-11-26

申请号：EP13405063.2

申请日：2013-05-22

申请人： Studer, Daniel, Dr.

发明人： Studer, Daniel, Dr.

IPC分类号： G01N1/06 ,  G01N1/28 ,  G02B21/32 ,  G02B21/34

CPC分类号： B26D7/01 ,  G01N1/06 ,  G01N1/2813 ,  G01N1/42 ,  H01J2237/20 ,  Y10T83/6572

摘要： Die Vorrichtung zur Übertragung von Schnittbändern auf Probenhalter für die Transmissions- Elektronenmikroskopie (TEM) weist zwei voneinander unabhängige Werkzeuge (4) und (17) einerseits für die Manipulation der Schnittbänder und andererseits für die Manipulation der Probenhalter (grids) auf, welche während des Schneidvorganges selbständig durch zwei voneinander unabhängige Mikromanipulatoren (3) und (10) positionierbar sind. Das Werkzeug (4) zur Manipulation der Schnittbänder (24) umfasst ein Metrallrohr (13), ein Rohr aus einem elektrisch isolierenden Werkstoff (14) sowie eine auswechselbare Spitze (5). In dieser Spitze (5) ist eine mit einer elektrisch leitenden Oberflächenschicht versehene elastische Faser (16) aus dielektrischem Material auswechselbar eingesetzt, welche zur schonenden Handhabung der Schnittbänder verwendet wird.

摘要翻译： 的器件具有两个相互独立的工具来操纵所述第一部分和带第二操纵试样保持器（网格）。 每个工具可以在切割过程中通过两个相互独立的微操纵器被定位unabhängig。 用于操纵部色带该工具有一个金属管，可交换的尖端的电绝缘材料和管。 装配有在导电表面包覆介电材料制成的弹性纤维可更换地安装在所述尖端和用于部分带的小心搬运。

公开(公告)号：EP2064708B1

公开(公告)日：2014-11-12

申请号：EP07823909.2

申请日：2007-09-20

申请人： The University Court of the University of St. Andrews

发明人： MACDONALD, Michael ,  DHOLAKIA, Kishan ,  RHODES, Daniel ,  MILNE, Graham

IPC分类号： G21K1/00 ,  G01N1/10 ,  G02B21/32

CPC分类号： G01N15/0205 ,  G01N1/40 ,  G01N2015/149 ,  G02B21/32

公开(公告)号：EP2776215A1

公开(公告)日：2014-09-17

申请号：EP12848073.8

申请日：2012-11-06

申请人： Sensapex Oy

发明人： VÄHÄSÖYRINKI, Mikko

IPC分类号： B25J7/00 ,  G02B21/32

CPC分类号： B25J7/00 ,  B25J19/0016 ,  G02B21/32 ,  H02N2/02 ,  H02N2/025

摘要： The invention relates to a micromanipulator arrangement comprising at least one drive stem (120, 821), at least one movable element (130, 320, 360) arranged on the drive stem (120, 821) to move along the drive stem (120, 821 ) wherein the drive stem (120, 821) being arranged to cause a change in a position of the movable element (130, 320, 360) with respect to the drive stem (120, 821); wherein an additional factor exists having an effect in the change of the position of the movable element and the micromanipulator arrangement further comprises means (870) for compensating said additional factor such that said effect is diminished.

公开(公告)号：EP2550522A4

公开(公告)日：2014-07-23

申请号：EP11760112

申请日：2011-03-23

申请人： CALIFORNIA INST OF TECHN

发明人： ZHENG GUOAN ,  YANG CHANGHUEI ,  YANG SAMUEL ,  LEE SEUNG AH

IPC分类号： G01N21/49 ,  G01N35/00 ,  G02B21/32

CPC分类号： H04N5/349 ,  G01N15/147 ,  G01N15/1484 ,  G02B21/0008 ,  G02B21/36 ,  G06T3/4053

摘要： A super resolution optofluidic microscope device comprises a body defining a fluid channel having a longitudinal axis and includes a surface layer proximal the fluid channel. The surface layer has a two-dimensional light detector array configured to receive light passing through the fluid channel and sample a sequence of subpixel shifted projection frames as an object moves through the fluid channel. The super resolution optofluidic microscope device further comprises a processor in electronic communication with the two-dimensional light detector array. The processor is configured to generate a high resolution image of the object using a super resolution algorithm, and based on the sequence of subpixel shifted projection frames and a motion vector of the object.

公开(公告)号：EP2730962A2

公开(公告)日：2014-05-14

申请号：EP13182832.9

申请日：2013-09-03

申请人： AOSense, Inc.

发明人： Loftus, Thomas H. ,  Vitouchkine, Artyom ,  Matthews, Michael R. ,  Black, Adam T. ,  Teper, Igor ,  Hollberg, Leo W. ,  Gustavson, Todd L. ,  Young, Brent C.

IPC分类号： G02B21/32 ,  H05H3/04

摘要： The device for producing laser-cooled atoms comprises a two dimensional trap or a three-dimensional trap, or a combination of two- and three-dimensional traps. The two-dimensional trap comprises: three or more permanent magnets arranged around a perimeter of a loop, wherein a plane of the loop is perpendicular to a free axis of the two-dimensional atom trap, and the three or more permanent magnets bracket an internal volume of the two-dimensional atom trap; and one or more laser beam input ports enabling access for one or more laser beams to the internal volume of the two-dimensional atom trap.

摘要翻译： 用于生产激光冷却原子的装置包括二维阱或三维阱，或二维和三维陷阱的组合。 二维陷阱包括：围绕环周围布置的三个或更多个永磁体，其中所述环的平面垂直于所述二维原子阱的自由轴，并且所述三个或更多个永磁体将内部 体积的二维原子阱; 以及一个或多个激光束输入端口，其使得能够访问一个或多个激光束到二维原子阱的内部体积。

公开(公告)号：EP2279444A4

公开(公告)日：2014-01-01

申请号：EP08733626

申请日：2008-03-19

申请人： UNIV TORONTO

发明人： SUN YU ,  WANG WENHUI

IPC分类号： G02B21/32 ,  C12M1/00 ,  C12M1/26 ,  C12M3/00 ,  C12N15/89

CPC分类号： C12N15/89 ,  C12M23/50 ,  C12M35/02 ,  G02B21/32