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81.发明公开ORAL DISINFECTANT, FOOD ADDITIVE COMPRISING THE DISINFECTANT 有权MUNDDESINFEKTIONSMITTEL UND NAHRUNGSMITTELZUSATZ MIT DIESEM DESINFEKTIONSMITTEL
公开(公告)号：EP2127667A1
公开(公告)日：2009-12-02
申请号：EP07767787.0
申请日：2007-06-28
IPC分类号： A61K38/44 , A23L1/30 , A61K31/19 , A61K31/194 , A61K31/198 , A61K31/7004 , A61P1/02 , A61P31/04
CPC分类号： A61K38/44 , A23C9/1213 , A23C13/16 , A23L29/06 , A23L33/10 , A61K31/19 , A61K31/194 , A61K31/198 , A61K31/7004 , A61K38/443 , C12Y101/03004 , C12Y111/01007 , A61K2300/00
摘要： Disclosed is a disinfectant which is safe, has few adverse side-effects, can be ingested together with a food or beverage by adding the disinfectant to the food or beverage, shows a bactericidal effect in the oral cavity, and has no problem even when ingested on a daily basis over a long period. Also disclosed is a food additive comprising the disinfectant. Specifically, disclosed is an oral disinfectant for the disinfection of an oral bacterium, which comprises lactoperoxidase, glucose oxidase, glucose and a pH-adjusting component.
摘要翻译： 公开了一种消毒剂，其是安全的，具有很少的副作用，可以通过向食品或饮料中加入消毒剂与食物或饮料一起摄取，在口腔中显示杀菌作用，即使摄入也没有问题 长期以来每天都有。 还公开了包含消毒剂的食品添加剂。 具体地，公开了用于消毒口腔细菌的口腔消毒剂，其包括乳过氧化物酶，葡萄糖氧化酶，葡萄糖和pH调节组分。
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公开(公告)号：EP2059606A2
公开(公告)日：2009-05-20
申请号：EP07814724.6
申请日：2007-09-06
发明人： CHILKOTI, Ashutosh
CPC分类号： A61K38/26 , A61K38/00 , A61K38/162 , A61K38/1709 , A61K38/177 , A61K38/1796 , A61K38/212 , A61K38/28 , A61K38/39 , A61K38/443 , A61K38/4873 , A61K47/6435 , C07K14/78 , C07K2319/01
摘要： Therapeutic compositions containing fusion proteins (FPs) including elastin-like peptides (ELPs) and peptide active therapeutic agents, and methods of making and using such compositions and fusion proteins. Therapeutic compositions of such type enable improved efficacy of the peptide active therapeutic agent to be achieved, in relation to the peptide active therapeutic agent alone. Enhanced efficacy of the peptide active therapeutic agent in the therapeutic composition may include improved solubility, bioavailability, bio-unavailability, half-life, etc., as compared to corresponding compositions containing the same peptide active therapeutic agent without associated ELPs.
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83.发明公开AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE 有权MITTEL ZUR VERWENDUNG BEI FRUCTOSE-UNVERTRÄGLICHKEIT
公开(公告)号：EP1951290A4
公开(公告)日：2009-03-11
申请号：EP06820896
申请日：2006-11-15
CPC分类号： A61K38/47 , A23L5/20 , A23L29/06 , A23V2002/00 , A61K9/48 , A61K38/443 , A61K38/52 , C12Q1/32 , C12Y101/01124 , C12Y302/0102 , C12Y302/01026 , C12Y503/01005 , G01N2333/904 , G01N2800/04 , G01N2800/38 , A23V2200/328 , A61K2300/00
摘要： The invention provides a 5-D-fructose dehydrogenase, optionally in combination with invertase and/or maltase and/or glucose isomerase, for use in medicine, preferably in the form of a pharmaceutical composition. More particularly, the invention provides a 5-D-fructose dehydrogenase, optionally in combination with invertase and/or maltase and/or glucose isomerase, for use in the therapy of fructose intolerance.
摘要翻译： 本发明涉及在果糖不耐受的情况下使用的药剂，以及通过施用果糖或果糖的食品或通过在消化道中释放果糖而引起的健康和健康的任何形式的损伤和损害 人或动物来自其他物质，例如 蔗糖。 根据本发明的药剂包含5-D-果糖脱氢酶，任选地与转化酶和/或麦芽糖酶和/或葡萄糖异构酶组合，该酶或酶的组合在医疗领域中首次使用。 优选地，试剂是药物组合物的形式，其可用于治疗果糖不耐症。
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84.发明公开SYNERGISTIC EFFECT BETWEEN A CYANOGENIC SYSTEM AND ANOTHER OXIDATIVE INDUCER FOR THE TREATMENT OF TUMOURS 审中-公开BETWEEN氰生成系统和肿瘤INDUKTOR到另一个氧化处理协同效应
公开(公告)号：EP2003197A2
公开(公告)日：2008-12-17
申请号：EP06841754.2
申请日：2006-12-22
CPC分类号： A61K38/45 , A61K38/443
摘要： The invention relates to a system capable of causing the death of tumor cells by activating caspase-independent apoptosis, comprising:
I. a cyanogenic system comprising the enzymatic activity exerted by linamarase on linamarin and an oxidative stress inducing system comprising the oxidative activity by the glucose oxidase enzyme combined in a single composition or
II. a cyanogenic system comprising the enzymatic activity exerted by linamarase on linamarin and an oxidative stress inducing system comprising the oxidative activity exerted by the glucose oxidase enzyme present in independent compositions.摘要翻译： 本发明涉及一个系统，它能够通过激活胱天蛋白酶非依赖性细胞凋亡，包括使肿瘤细胞死亡的：I.一氰生成系统包含通过亚麻苦苷酶对琳娜·马林发挥的酶活性，并氧化应激诱导系统由葡萄糖包含的氧化活性 氧化酶组合在单个组合物或II。一个氰生成系统包含通过上琳娜·马林亚麻苦苷酶发挥的酶活性和氧化应激诱导系统，其包括由存在于组合物独立葡萄糖氧化酶所发挥的氧化活性。
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公开(公告)号：EP0910342B1
公开(公告)日：2008-12-17
申请号：EP97935238.2
申请日：1997-07-11
CPC分类号： A61K9/0024 , A61K9/0019 , A61K38/28 , A61K38/443 , A61K38/482 , A61K38/4826 , A61K47/10 , Y10S514/944
摘要： Pharmaceutical compositions for the delivery of pharmacologically active proteins are provided by the present invention. The compositions of the present invention comprise a polymeric matrix having thermal gelation properties in which is incorporated a discrete suspension of at least one biologically active macromolecular polypeptide which retains greater than 90 percent of its biological activity. Furthermore, the concentration of the macromolecular polypeptide is greater than 0.5 percent by weight of the composition.
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公开(公告)号：EP1893187B1
公开(公告)日：2008-11-19
申请号：EP06741316.1
申请日：2006-06-13
申请人： Flen Pharma N.V.
CPC分类号： A61L26/008 , A01N31/16 , A01N35/04 , A01N37/40 , A61K31/05 , A61K33/40 , A61K38/44 , A61K38/443 , A61L26/0066 , A61L2300/11 , A61L2300/216 , A61L2300/254 , A61L2300/45 , A61L2300/802 , C12Y101/03004 , C12Y111/01007 , A01N37/46 , A01N59/00 , A01N59/16 , A01N61/00 , A01N2300/00 , A61K2300/00
摘要： The present invention discloses a class of compounds which have an enhancing effect on peroxidase based antimicrobial compositions. The invention relates to pharmaceutical compositions for prolonged topical use comprising enhancing agents such as methoxyphenols and substituted benzylaldehydes. Examples hereof are respectively guaiacol and vanillin.
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87.发明公开Pharmazeutische Zusammensetzungen, die Diaminooxidase enthalten 有权Pharmazeutische Zubereitungen als水凝胶，死二氨基氧化酶焓
公开(公告)号：EP1782824A2
公开(公告)日：2007-05-09
申请号：EP07101239.7
申请日：2005-07-06
申请人： Missbichler, Albert
CPC分类号： A61K9/16 , A23L29/06 , A23L29/262 , A23L33/10 , A23L33/18 , A61K9/06 , A61K9/1623 , A61K9/1652 , A61K9/50 , A61K38/44 , A61K38/443 , C12Y104/03006
摘要： Die vorliegende Erfindung betrifft pharmazeutische Zusammensetzungen und kosmetische Zusammensetzungen umfassend Diaminooxidase und deren Verwendung.
摘要翻译： 用于治疗组胺诱导的疾病的新药物组合物（I），其包含二胺氧化酶（DAO），由表皮，口服，口服或舌下给药的剂型组成，作为水凝胶，胃液抗性丸剂，滴剂（特别是滴眼剂或滴鼻剂 ）或平板电脑，是新的。 还包括独立权利要求：（1）含DAO的营养补充剂组合物或饮食食品（特别是胃液耐药丸，滴剂或输注物）; （2）含DAO的化妆品组合物（特别是以水凝胶，软膏，喷雾剂或滴剂的形式）; 和（3）使用DAO（对制剂类型没有限制）用于生产用于治疗组胺诱发的疾病的药物。 活动：皮肤病学; 抗过敏; 止痒; 解毒剂。 在6/6神经性皮炎/皮肤病患者（比两种情况下比可的松软膏更有效），5/5接触过敏患者和1/2昆虫的情况下，将稳定地并入水凝胶中的DAO的局部应用 咬病人 作用机理：组胺的酶降解。
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公开(公告)号：EP1763363A1
公开(公告)日：2007-03-21
申请号：EP05758617.4
申请日：2005-07-06
申请人： Missbichler, Albert
CPC分类号： A61K9/16 , A23L29/06 , A23L29/262 , A23L33/10 , A23L33/18 , A61K9/06 , A61K9/1623 , A61K9/1652 , A61K9/50 , A61K38/44 , A61K38/443 , C12Y104/03006
摘要： The invention relates to pharmaceutical compositions, food supplement compositions and cosmetic compositions which contain diaminooxidase and to the use thereof.
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89.发明公开POWDERED COMPOSITIONS OF SENSITIVE ACTIVE MATERIALS IN AN AT LEAST PARTIALLY AMORPHOUS STATE 审中-公开敏感的活性成分。在一个至少部分非晶态的粉末组合物
公开(公告)号：EP1720525A1
公开(公告)日：2006-11-15
申请号：EP05717822.0
申请日：2005-02-28
CPC分类号： A61K9/19 , A61K35/74 , A61K35/76 , A61K38/443 , A61K38/50 , A61K38/51 , A61K45/06 , A61K47/26 , A61K47/36 , A61K47/42
摘要： The invention provides a powdered formulation which is a freeze-dried mixture of a sensitive active material and an excipient containing: 0.1-50% by wt of the sensitive active material, 50-99.99% by wt of the excipient, wherein at least 0.1% by wt of the mixture is an amorphous state; the formulation has a substantially reduced hygroscopicity.
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公开(公告)号：EP0910342A4
公开(公告)日：2006-03-22
申请号：EP97935238
申请日：1997-07-11
申请人： UNIV COLORADO
CPC分类号： A61K9/0024 , A61K9/0019 , A61K38/28 , A61K38/443 , A61K38/482 , A61K38/4826 , A61K47/10 , Y10S514/944
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