Abstract:
A spectrophotometer of the type using a pulse motor (P) to rotate a diffraction grating (G) through a speed reducing mechanism (B) has a capability of constructing a conversion table according to a program, by which table a rotation amount of the motor (P) is converted to a corresponding wavelength of output light from a monochromator (MC). The spectrophotometer is capable of designating a calibration mode in which an emission peak at a known wavelength of light from a light source is detected, a coefficient in a conversion equation is determined on the basis of the known wavelength of the emission peak and a rotation amount of the motor (P) at a time when the emission peak is detected, and the determined coefficient is used to construct the conversion table which is then stored in a nonvolatile memory. In an analysis mode, a rotation amount of the motor (P) is converted to a corresponding wavelength in accordance with the conversion table in the nonvolatile memory.
Abstract:
Monochromateur avec une source d'entrée (5) au foyer d'un miroir (2) concave qui envoie un faisceau parallèle sur un réseau plan (1) et recevant en retour les faisceaux diffractés pour les focaliser sur une ou plusieurs sorties (6) sélectives des longueurs d'onde. L'entrée (5) et les sorties (6) sont constituées par des fibres optiques engagées dans un orifice (4) formé dans le réseau (1), dans l'axe de la normale au sommet du miroir (2). Le réseau est déterminé pour recueillir les longueurs d'onde recherchées au voisinage de l'axe du miroir (2).
Abstract:
A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
Abstract:
The present invention relates to a spectrometer (100) for analysing the spectrum of an upstream light beam (1) comprising an entrance slit (101) and angular dispersing means (130). According to the invention, the angular dispersing means comprise at least one polarisation-dependent diffraction grating that is suitable for, at the plurality of wavelengths (11, 12, 13), diffracting a corrected light beam (20) into diffracted light beams (31, 32, 33) in a given particular diffraction order of the polarisation-dependent diffraction grating, which is either the +1 diffraction order or the -1 diffraction order, when the corrected light beam has a preset corrected polarisation state that is circular; and the spectrometer comprises means for modifying polarisation (1100) placed between the entrance slit and the angular dispersion means, which means are suitable for modifying the polarisation state of the upstream light beam in order to generate the corrected light beam with a preset corrected polarisation state.
Abstract:
A manufacturing method for a grating is disclosed for the angular dispersion of light impinging the grating. The grating comprises tapered structures and cavities. A cavity width and/or corrugation amplitude is varied for achieving a desired grating efficiency according to calculation. A method is disclosed for conveniently creating gratings with variable cavity width and/or corrugation amplitude. The method comprises the step of anisotropically etching a groove pattern into a grating master. Optionally a replica is produced that is complementary to the grating master. By variation of an etching resist pattern, the cavity width of the grating may be varied allowing the optimization towards different efficiency goals.