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    HYDROGEL COMPOSITIONS BONDED TO POLYMERIC SUBSTRATES
    81.
    发明公开
    HYDROGEL COMPOSITIONS BONDED TO POLYMERIC SUBSTRATES 审中-公开

    公开(公告)号：EP3356485A1

    公开(公告)日：2018-08-08

    申请号：EP16852358.7

    申请日：2016-09-26

    申请人： 3M Innovative Properties Company

    发明人： YOUNG, Alexi J. ,  RASMUSSEN, Jerald K.

    IPC分类号： C09J7/02 ,  A61L26/00 ,  A61L15/60 ,  C09J11/04 ,  C08J3/075 ,  C08L33/10 ,  C08L33/26

    摘要： Described herein is a multilayer article comprising: a. a polymer substrate comprising an abstractable atom; and b. a hydrogel coating thereon wherein the hydrogel coating has a water content of at least 10 wt % and is covalently bonded to the polymer substrate, and wherein the hydrogel coating is derived from an aqueous composition having a pH less than 9.5, the aqueous composition comprising: (a) a hydrophilic monomer selected from at least one of (meth)acrylate or (meth)acrylamide; (b) at least 0.1 wt % of a water-swellable clay; (c) a first initiator, wherein the first initiator is water-soluble and is a Type I photoinitiator; and (d) a second initiator, wherein the initiator is water-soluble and is a Type II photoinitiator; and (e) an acid.

    MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED COLLAGEN LAYER
    83.
    发明公开
    MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED COLLAGEN LAYER 审中-公开
    具有穿孔胶原蛋白层的多层伤口护理产品

    公开(公告)号：EP3315145A1

    公开(公告)日：2018-05-02

    申请号：EP16196320.2

    申请日：2016-10-28

    申请人： BSN medical GmbH

    发明人： HEMMRICH, Karsten ,  BLUMENTHAL, Nils

    IPC分类号： A61L15/32 ,  A61L15/42 ,  A61L15/46 ,  A61L15/60

    CPC分类号： A61L15/32 ,  A61L15/325 ,  A61L15/425 ,  A61L15/46 ,  A61L15/60 ,  A61L2300/404

    摘要： The invention relates to a multi-layered wound care product comprising (a) an upper liquid-absorbing layer; (b) an intermediate bacteria-adsorbing layer; and (c) a liquid-permeable bottom layer comprising collagen, collagen-like protein or peptides comprising a matrix metalloprotease (MMP) cleavage site or a combination thereof. The invention further relates to the use of said multi-layered wound care product for plastic surgery, tissue engineering and for treatment of acute and chronic wounds and for use in vacuum therapy. The invention finally relates to a method of producing the multi-layered wound care product of the invention.

    摘要翻译： 本发明涉及多层伤口护理产品，其包含（a）上部液体吸收层; （b）中间细菌吸附层; 和（c）包含胶原蛋白，胶原蛋白样蛋白质或包含基质金属蛋白酶（MMP）裂解位点或其组合的液体可渗透底层。 本发明进一步涉及所述多层伤口护理产品用于整形手术，组织工程和用于治疗急性和慢性伤口并用于真空治疗的用途。 本发明最终涉及生产本发明的多层伤口护理产品的方法。