POLYMERS WITH REDUCED ESTROGENIC ACTIVITY
    8.
    发明公开
    POLYMERS WITH REDUCED ESTROGENIC ACTIVITY 审中-公开
    POLYMERE MIT REDUZIERTERÖSTROGENWIRKUNG

    公开(公告)号:EP2714772A1

    公开(公告)日:2014-04-09

    申请号:EP12723207.2

    申请日:2012-05-24

    IPC分类号: C08G75/20 C08G65/38

    摘要: A polymer which comprises recurring units derived from at least one monomer (M) having a general formula (I) Y
    1 -Z
    1 -Q-Z
    2 -Y
    2 wherein Y
    1 and Y
    2 , equal or different from each other, are independently selected from a group consisting of OH, SH, C1, Br, NO
    2 or I; Z
    1 and Z
    2 , equal or different from each other, independently comprises at least 1 aromatic ring and, Q comprises at least one hydrophilic moiety (H) selected from the group consisting of a sulfone (SO
    2 ), a ketone (CO), a phosphine oxide (PO), an ether, a thioether, an ester, an anhydride, a carbonate, an amide, an imide, an imine and an urethane group, and the interatomic distance between Y
    1 and Y
    2 is at least 10 Å, the monomer has an EC
    50 response value to the estrogen receptor a (ERα) equal to or at least 26000 nM.

    摘要翻译: 包含衍生自具有通式(I)Y1-Z1-Q-Z2-Y2的至少一种单体(M)的重复单元的聚合物,其中Y1和Y2彼此相同或不同,独立地选自 的OH,SH,Cl,Br,NO 2或I; Z 1和Z 2彼此相同或不同,独立地包含至少1个芳香环,Q包含至少一个亲水部分(H),其选自砜(SO 2),酮(CO),膦 氧化物(PO),醚,硫醚,酯,酸酐,碳酸酯,酰胺,酰亚胺,亚胺和氨基甲酸酯基,Y1和Y2之间的原子间距离至少为10,单体具有 雌激素受体a(ERα)的EC 50应答值等于或至少26000nM。

    PORÖSE HOHLFASER
    10.
    发明公开
    PORÖSE HOHLFASER 审中-公开
    中空纤维多孔

    公开(公告)号:EP2598232A1

    公开(公告)日:2013-06-05

    申请号:EP11775726.0

    申请日:2011-07-28

    摘要: The invention relates to a porous hollow fiber comprising first pores which have an average length in a range of 0.045 μm to 120 μm and an average width in the range of 0.030 μm to 20 μm, each measured in the fiber direction, wherein the ratio of the average length of the first pores to the average width of the first pores is at least 1.5:1. The hollow fibers further comprise second pores which have an average length in the range of 0.1 nm to 99 nm and an average width in the range of 1 nm to 20000 nm, each measured in the fiber direction, wherein the ratio of the average length of the second pores to the average width of the second pores is 1:1.5 at maximum. Preferred application areas of the porous hollow fibers according to the invention comprise use thereof in fillings, in selectively permeable membranes, for the immobilization of enzymes and/or cells, for hemodialysis and for storage of hydrogen.