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2.发明公开
公开(公告)号：EP4375294A1
公开(公告)日：2024-05-29
申请号：EP22846209.9
申请日：2022-07-20
发明人： KIM, Yong Sung , LEE, Dasom , SEO, Jisu , KWEON, Hae Jin , KIM, Dae-Seong
摘要： The present invention relates to: a cell-penetrating degrading antibody in which U-Box of E3 that can bind to E2 of an ubiquitin-proteasome system (UPS), which is an intracellular protein degradation system, or an E3 recruiter (E3 recruiting ligand) that can bind to E3 of the UPS is fused to a cell-penetrating interfering antibody that penetrates into the cytosol of living cells and specifically recognizes a target protein; a composition comprising same; and use thereof.
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3.发明授权
公开(公告)号：EP3581175B1
公开(公告)日：2023-12-13
申请号：EP18751180.3
申请日：2018-02-08
发明人： KIM, Moon Suk , HEO, Ji Yeon
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公开(公告)号：EP3335760B1
公开(公告)日：2021-09-29
申请号：EP16835444.7
申请日：2016-08-10
发明人： KIM, Chul Ho , KANG, Sung Un , CHOI, Jae Won
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公开(公告)号：EP2392191B1
公开(公告)日：2021-06-30
申请号：EP10736078.6
申请日：2010-02-02
发明人： OH, Seong-Keun , LEE, Min
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公开(公告)号：EP3266865B1
公开(公告)日：2021-01-27
申请号：EP16761938.6
申请日：2016-03-04
发明人： SUH, Hae Young , KIM, Sung Soo , CHANG, Da Young , JUNG, Jin Hwa , LEE, Young Don , HWANG, Woo Sup , PARK, Jin Sung , LEE, Su Jung
IPC分类号： A61P1/00 , C12N5/0775 , C12N5/077 , A61K35/12 , A61K31/506 , A61K31/4188 , A61K31/4745 , A61K33/24 , A61K31/675 , A61K31/704 , A61K31/513 , A61K45/06 , A61K35/02
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公开(公告)号：EP3718554A1
公开(公告)日：2020-10-07
申请号：EP18882507.9
申请日：2018-11-23
发明人： JUNG, Yi Sook , KIM, Tae Ho
IPC分类号： A61K36/535 , A23L33/105
摘要： The present invention relates to a pharmaceutical composition or health functional food composition comprising a Perilla frutescens fermented extract for prevention or treatment of a sleep disorder. In addition, the present invention relates to a composition or a fiber or fragrance composition comprising a Perilla frutescens fermented extract for sleep improvement. In addition, the present invention relates to a method for treatment of a sleep disorder, the method comprising a step of administering a Perilla frutescens fermented extract to a patient with a sleep disorder. In addition, the present invention relates to a use of a Perilla frutescens fermented extract for use in the preparation of a composition for treatment of a sleep disorder or for prevention or treatment of a sleep disorder. Therefore, in the present invention, the Perilla frutescens fermented extract, compared with an unfermented Perilla frutescens extract, significantly shortens sleep latency and significantly increases total sleeping time, and thus the Perilla frutescens fermented extract is effective as a composition for prevention, alleviation, or treatment of a sleep disorder or for sleep improvement, and can be also effectively used in a treatment method for a sleep disorder.
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公开(公告)号：EP2599230B1
公开(公告)日：2020-07-08
申请号：EP11812763.8
申请日：2011-07-27
发明人： OH, Seong Keun , KIM, Jae Hyun , LEE, Min , LEE, Hyun Jin , KIM, Ji Su
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公开(公告)号：EP3323894B1
公开(公告)日：2020-03-11
申请号：EP16811916.2
申请日：2016-06-15
发明人： LEE, Pyung Cheon , KIM, Jin Ho
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公开(公告)号：EP2744120B1
公开(公告)日：2019-10-09
申请号：EP12823529.8
申请日：2012-08-10
发明人： OH, Seong-Keun , LEE, Min
IPC分类号： H04B7/06 , H04B7/0404 , H04B7/08 , H04B7/022
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