-
公开(公告)号：EP3472183B1
公开(公告)日：2023-08-09
申请号：EP17734575.8
申请日：2017-06-15
发明人： DUDMAN, Joshua , HANTMAN, Adam , LOOGER, Loren , RITOLA, Kimberly , SCHAFFER, David , TERVO, Dougal Gowanlock Robinson , VISWANATHAN, Sarada , HWANG, Bum-Yeol , KARPOVA, Alla
IPC分类号： C07K14/015 , C12N7/01 , A61K48/00
-
公开(公告)号：EP3207131B1
公开(公告)日：2022-09-28
申请号：EP15850739.2
申请日：2015-10-16
发明人： SINGER, Robert , DENG, Wulan , LIONNET, Timothee
IPC分类号： C12Q1/68 , C12Q1/6804 , C12Q1/6841 , C12N15/01
-
公开(公告)号：EP3540064B1
公开(公告)日：2022-07-27
申请号：EP19160143.4
申请日：2013-10-10
发明人： LOOGER, Loren , SVOBODA, Karel , KIM, Douglas , KERR, Rex
IPC分类号： C12N15/12 , C12N15/85 , C07K14/435 , G01N33/68
-
公开(公告)号：EP3126451B1
公开(公告)日：2020-09-09
申请号：EP15774408.7
申请日：2015-04-01
发明人： LAVIS, Luke, D. , GRIMM, Jonathan, B. , CHEN, Jiji , LIONETTE, Timothee , ZHANG, Zhengjian , REVYAKIN, Audrey , SLAUGHTER, Joel
IPC分类号： C09B57/02 , C07D311/06 , A61K31/37 , A61K31/397 , C09B57/14 , C07D405/04 , C07D413/04
-
公开(公告)号：EP3069367B1
公开(公告)日：2019-01-09
申请号：EP14859522.6
申请日：2014-11-11
发明人： PRICE, John, H. , BOCK, Dravida
-
公开(公告)号：EP2802861A1
公开(公告)日：2014-11-19
申请号：EP13736386.7
申请日：2013-01-11
发明人： ABRAHAMSSON, Sara
CPC分类号： G02B27/4205 , G02B21/367 , G02B27/0075 , G02B27/1086 , G02B27/4211
摘要： An optical imaging system includes a first diffractive optical element that receives a multi-wavelength beam of light and separates the received beam of light into diffractive orders. The optical imaging system also includes a second diffractive optical element that includes panels displaced along the second diffractive element in at least one direction, where each panel is positioned to receive and pass the multi-wavelength beam of one of the diffractive orders. A refractive optical element is positioned to receive multi-wavelength beams of the diffractive orders that pass through the second diffractive element, and an optical lens that receives the multi-wavelength beams of the diffractive orders that pass through the refractive element and focuses each of the multi-wavelength beams of the diffractive orders to a different location on an image plane at the same time.
-
公开(公告)号：EP2496697A2
公开(公告)日：2012-09-12
申请号：EP10829090.9
申请日：2010-11-04
发明人： LOOGER, Loren, Lee , TIAN, Lin
IPC分类号： C12N15/12 , C12Q1/68 , C07K14/705 , G01N33/68
CPC分类号： C07K14/4728 , C07K2319/60 , G01N33/5035
摘要： Provided herein are nucleic acid sequences and polypeptides encoding a genetically encoded calcium indicator (GECI). Also provided are vectors and cells comprising the nucleic acid sequences and/or polypeptides. Kits comprising the nucleic acid sequences, polypeptides, vectors, cells and combinations thereof are also provided. Also provided herein are methods of screening for G-protein coupled receptor (GPCR) agonists and antagonists and methods of monitoring neural activity using the GECIs.
-
公开(公告)号：EP2452221A1
公开(公告)日：2012-05-16
申请号：EP10737408.4
申请日：2010-07-09
发明人： BETZIG, Eric , JI, Na
摘要： Microscopy techniques in which a rear pupil of an optical system is segmented and the segments are individually controlled with a wavefront modulating device to control the direction and phase of individual beamlets of an excitation or emission beam in the optical system, thereby providing an adaptive optics correction to sample and system induced aberrations.
-
公开(公告)号：EP0400047B1
公开(公告)日：1997-04-23
申请号：EP89902467.3
申请日：1989-02-02
CPC分类号： C12N15/86 , A61K38/00 , A61K48/00 , C07K14/635 , C07K14/705 , C12N2710/10243 , C12N2740/13043 , Y10S435/948
摘要： Genetically engineered or transduced hepatocytes which express genetic material of interest introduced or incorporated into them, as well as methods of producing, transplanting and using the genetically engineered hepatocytes. The genetic material of interest can be incorporated through use of a vector, such as a recombinant retrovirus, which contains the genetic material of interest, or by other means.
-
公开(公告)号：EP0391960B1
公开(公告)日：1994-08-17
申请号：EP89900771.0
申请日：1988-12-08
CPC分类号： C12N15/86 , A61K35/44 , A61K38/177 , A61K38/29 , A61K38/47 , A61K48/00 , A61K2035/124 , A61L27/38 , C12N5/069 , C12N2740/16043 , C12Y302/01023 , A61K2300/00
摘要： Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionnally, a selectable marker, as well as methods for making and using the transduced endothelial cells. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone or a drug, to an individual who has had a graft or implant of the transduced cells.
-
-
-
-
-
-
-
-
-
搜索结果
61 条记录 (耗时 0.039 秒)
