摘要:
The invention concerns solid foamed active substance preparations based on thermoplastically processed polymers obtained by extruding an active-substance-containing melt of one or a plurality of polymers which is impregnated and expanded with a volatile, physiologically harmless expanding agent.
摘要:
The invention concerns solid medicaments obtained by extrusion with subsequent shaping of a solvent-free melt, containing in addition to one or a plurality of active substances: A) between 10 and 90 wt.% of a thermoplastically processable water-soluble polymer; B) between 5 and 85 wt.% isomalt; and C) between 0 and 5 wt.% lecithin, the total of all the contents equalling 100 wt.%.
摘要:
The present invention concerns water-soluble or water-dispersible polyurethanes prepared from a water-dispersible polyurethane prepolymer that contains terminal isocyanate groups and a primary or secondary amine that contains at least one ionogen or ionic group. The invention also concerns the salts of said polyurethanes. The polyurethanes claimed in the invention find use in Cosmetics and Pharmacy and particularly as hair fixer with improved rinseability.
摘要:
In a cationic modification process for starch, starch is reacted with polymers that contain amino and/or ammonium groups in an aqueous medium at temperatures from 115 to 180 °C under an increased pressure and in the absence of oxidisers, polymerisation initiators and alkali. The reaction is conducted so that maximum 10% by weight starch has its molar weight reduced. Also disclosed is the use of the thus obtained reaction products as dry strength agents for paper.
摘要:
The invention concerns a process for preparing nitrobiphenylene of formula (I) wherein m stands for 1 or 2, R means halogen, R' or OR', R' being a C-organic group which can carry groups which are inert in the reaction conditions, n stands for 0, 1, 2 or 3 and, if n is 2 or 3, the R groups can also be different. According to the invention, a chloronitrobenzene of formula (II) is reacted in the presence of a palladium catalyst and a base in a solvent with a phenyl boric acid (IIIa), one of its alkyl esters of formula (IIIb), R1 meaning C¿1?-C6 alkyl, or one of its anhydrides. The compounds (I) are suitable as initial products for biphenylamines which are in turn intermediate products for fungicidal plant-growth substances.
摘要:
Novel dolasstatin derivatives of the formula (I): R1R2N-CHX-CO-A-B-D-E-(F)¿t?K, in which R?1, R2¿, A, B, D, E, F, K, X and t have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
摘要:
The present invention provides anti-tumor peptides of the Formula (I), A-B-N(CH3)-CHD-CH(OCH3)-CH2CO-Pro-Pro-K, and the acid salts thereof. A is an amino acid residue of the formula (CH3)2N-CHX-CO, wherein X is a normal or branched alkyl group. B is an amino acid residue selected from the group consisting of valyl, isoleucyl, leucyl, and 2-t-butylglycyl. D is a normal or branched C3-C4-alkyl group. K is a t-butoxy group or a substituted amino group. An additional embodiment of the present invention is a method for treating a malignancy in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound or compounds of Formula (I) in a pharmaceutically acceptable composition.
摘要:
Amino and/or alkoxy triazines with at least one C1-C10alkyl group which has a vinyl sulphonyl group or a radical promoting the formation of a vinyl sulphonyl group and is also possibly substituted, their use as fixing auxiliaries in the colouring of organic substrates with hydroxy groups or nitrogen atoms by means of anionic colorants and as cross-linking agents for regenerated cellulose or cellulose-containing materials.
摘要:
Novel peptides of the following formula (I): R1R2N-CHX-CO-A-B-D-E-(G)¿s?-K in which R?1, R2¿, A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.