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1.发明公开
公开(公告)号：EP3684374A1
公开(公告)日：2020-07-29
申请号：EP18859097.0
申请日：2018-09-21
申请人： Riboscience LLC
发明人： SMITH, Mark , KLUMPP, Klaus G.
IPC分类号： A61K31/7072 , A61K31/7076 , C07H19/04
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公开(公告)号：EP3647414A1
公开(公告)日：2020-05-06
申请号：EP18790650.8
申请日：2018-06-07
发明人： YAO, Bin , LUO, Huiying , LIU, Weina , GE, Jianzhong , TU, Tao , HUANG, Huoqing , SU, Xiaoyun , BAI, Yingguo , WANG, Yuan , WANG, Yaru , MENG, Kun
摘要： Provided are a glucose oxidase CnGODA, an encoding gene thereof, a recombinant expression vector comprising the gene, and a recombinant strain; the amino acid sequence of the glucose oxidase CnGODA is as represented in SEQ ID NO.1 or SEQ ID NO.2. Further provided is a method for use in preparing glucose oxidase CnGODA, and application of glucose oxidase CnGODA.
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3.发明公开
公开(公告)号：EP3569705A1
公开(公告)日：2019-11-20
申请号：EP17891647.4
申请日：2017-10-24
发明人： LI, Yangyuan , WANG, Jianrong , YANG, Ling , QU, Man , CHEN, Lizhi , HUANG, Jiale
摘要： The present invention relates to the field of genetic engineering, particularly to a method for efficiently expressing pullulanase in bacillus subtilis and recombinant bacillus subtilis. said method includes steps of constructing modified bacillus subtilis strain with deletion of alkaline protease gene and neutral protease gene, constructing expression vector including an optimized combination of promoter and signal peptide and pullulanase gene, and transforming said modified bacillus subtilis strain with by said expression vector. A series of combinations of promoter and signal peptide are optimized to obtain the combination for efficiently expressing pululanase, provide an industrial application basis.
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公开(公告)号：EP3137080B1
公开(公告)日：2019-09-04
申请号：EP15720242.5
申请日：2015-04-27
申请人： Orphomed, Inc.
发明人： SINGH, Nikhilesh
IPC分类号： A61K31/485 , A61P25/04 , C07D489/00 , C07C233/16 , A61K31/137 , A61K31/167
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公开(公告)号：EP2552944B1
公开(公告)日：2019-08-14
申请号：EP11712739.9
申请日：2011-03-28
IPC分类号： C07K14/195 , C07K14/21 , C07K14/245 , C07K14/285 , C07K16/12 , A61K38/16 , A61K39/02 , A61K39/102 , A61K39/104 , A61K39/108 , G01N33/569 , G01N33/68
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公开(公告)号：EP2410957B1
公开(公告)日：2019-08-14
申请号：EP10756932.9
申请日：2010-03-26
申请人： Llorens, Steven , Marcial, Maria
发明人： Llorens, Steven , Marcial, Maria
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7.发明公开
公开(公告)号：EP3509620A1
公开(公告)日：2019-07-17
申请号：EP17764662.7
申请日：2017-08-29
申请人： Nymox Corporation
发明人： AVERBACK, Paul
IPC分类号： A61K38/10 , A61P13/08 , A61K31/18 , A61K31/473 , A61K31/4985 , A61K31/505 , A61K31/517 , A61K31/58
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公开(公告)号：EP3490580A1
公开(公告)日：2019-06-05
申请号：EP17746197.7
申请日：2017-07-14
申请人： Nymox Corporation
发明人： AVERBACK, Paul
IPC分类号： A61K38/10 , A61K31/517 , A61P13/02
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公开(公告)号：EP3454800A1
公开(公告)日：2019-03-20
申请号：EP17722615.6
申请日：2017-04-27
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公开(公告)号：EP3072962B1
公开(公告)日：2018-12-26
申请号：EP13897309.4
申请日：2013-11-12
发明人： YAO, Bin , HUANG, Huoqing , LUO, Huiying , SHAO, Chao , BAI, Yingguo , WANG, Yaru , YANG, Peilong , SHI, Pengjun , MENG, Kun , ZHAO, Heng , MA, Rui
IPC分类号： C12N15/52
CPC分类号： C12N9/16 , A23K20/189 , C12N1/14 , C12N1/20 , C12N15/52 , C12N15/63 , C12Y301/03
摘要： The present invention relates to the field of genetic engineering, in particular, the present invention relates to a method for producing a phytase variant with an improved thermal stability, and a phytase variant and the use thereof. The phytase variant contains at least one proline modification, compared to the phytase from Escherichia coli and other mutants thereof. The phytase variants with the modification have preferably improved properties, such as the thermal stability, optimal reaction temperature, pH property, specific activity, protease resistance and performance in animal feeds.
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