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1.发明公开
公开(公告)号：EP3615572A1
公开(公告)日：2020-03-04
申请号：EP18726275.3
申请日：2018-04-27
申请人： Tesaro Inc. , AnaptysBio, Inc.
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公开(公告)号：EP2601217A2
公开(公告)日：2013-06-12
申请号：EP11815158.8
申请日：2011-08-02
申请人： AnaptysBio, Inc.
发明人： HORLICK, Robert , KING, David , BOWERS, Peter , DALTON, Jennifer , WU, Betty , ROBERTS, Traci , ZHANG, Xue , ALTOBELL III, Laurence
IPC分类号： C07K16/00 , A61K39/395 , C12N15/00 , C12N5/16 , C12P21/06
CPC分类号： C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/76 , C07K2317/92
摘要： The disclosure relates to an isolated IL-17-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1 and optionally an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The disclosure also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.
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公开(公告)号：EP4011914A1
公开(公告)日：2022-06-15
申请号：EP21198994.2
申请日：2016-02-03
申请人： AnaptysBio, Inc.
发明人： JUN, Helen Toni , KEHRY, Marilyn , BOWERS, Peter , KING, David J.
摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene-3 (LAG-3). The invention provides a LAG-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the LAG-3-binding agent to treat a disorder or disease that is responsive to LAG-3 inhibition, such as cancer or an infectious disease.
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公开(公告)号：EP3283110A1
公开(公告)日：2018-02-21
申请号：EP16780800.5
申请日：2016-04-15
申请人： AnaptysBio, Inc.
IPC分类号： A61K39/395 , A61P9/10 , A61P29/00 , A61P37/06
CPC分类号： C07K16/2866 , A61K39/395 , A61K39/39533 , A61K2039/505 , A61P29/00 , A61P37/06 , C07K2317/33 , C07K2317/76 , C07K2317/92
摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R). The invention provides an IL-36R-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-36R-binding agent to treat a disorder or disease that is responsive to IL-36R inhibition, such as cancer, an infectious disease, or an autoimmune disease.
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5.发明公开
公开(公告)号：EP3253798A2
公开(公告)日：2017-12-13
申请号：EP16747220.8
申请日：2016-02-03
申请人： AnaptysBio, Inc.
发明人： JUN, Helen Toni , KEHRY, Marilyn , BOWERS, Peter , KING, David J.
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06
CPC分类号： C07K16/2803 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61P31/00 , A61P35/00 , C07K16/2818 , C07K2317/24 , C07K2317/524 , C07K2317/70 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/30 , C07K2319/32 , Y02A50/386
摘要： The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene-3 (LAG-3). The invention provides a LAG-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the LAG-3-binding agent to treat a disorder or disease that is responsive to LAG-3 inhibition, such as cancer or an infectious disease.
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公开(公告)号：EP2601217B1
公开(公告)日：2017-06-14
申请号：EP11815158.8
申请日：2011-08-02
申请人： AnaptysBio, Inc.
发明人： HORLICK, Robert , KING, David , BOWERS, Peter , DALTON, Jennifer , WU, Betty , ROBERTS, Traci , ZHANG, Xue , ALTOBELL III, Laurence
IPC分类号： C07K16/00 , A61K39/395 , C12N15/00 , C12N5/16 , C12P21/06
CPC分类号： C07K16/244 , A61K2039/505 , C07K2317/21 , C07K2317/76 , C07K2317/92
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