公开(公告)号：EP4374862A1

公开(公告)日：2024-05-29

申请号：EP22846065.5

申请日：2022-06-27

申请人： Chung Ang University Industry Academic Cooperation Foundation

发明人： YOON, Yoo Sik ,  SIM, In Ae ,  LEE, Jong Kyu ,  LIM, Hye Mi

IPC分类号： A61K31/7048 ,  A61K36/65 ,  A61P21/00 ,  A23L33/125

CPC分类号： A61K36/65 ,  A61K31/7048 ,  A61P21/00 ,  A23L33/125

摘要： The present invention relates to a pharmaceutical composition for preventing or treating cachexia and muscle loss containing paeoniflorin. The pharmaceutical composition containing paeoniflorin may be used to effectively prevent or treat cachexia and muscle loss.

公开(公告)号：EP3760215A1

公开(公告)日：2021-01-06

申请号：EP19761453.0

申请日：2019-02-28

申请人： Chung Ang University Industry Academic Cooperation Foundation

发明人： YOON, Yoo Sik ,  JANG, Jae Woong ,  CHAE, Se Yeon ,  BAE, Tae Hyun ,  LEE, Hyun Ji ,  SONG, Jae Won

IPC分类号： A61K36/65 ,  A23L33/105 ,  A61P35/00

摘要： The present disclosure relates to a composition containing a Paeoniae radix extract as an active ingredient. The composition may alleviate inappetence, weight loss, muscle loss and fatigue and inhibit hematopoietic toxicity. Thus, the composition may be effectively used for the prevention, alleviation or treatment of cachexia and muscle loss.

公开(公告)号：EP3712518A1

公开(公告)日：2020-09-23

申请号：EP20160848.6

申请日：2020-03-04

申请人： LG Electronics Inc. ,  Chung Ang University Industry Academic Cooperation Foundation

发明人： JEON, Jongkeon ,  CHUNG, Haeyoong ,  KANG, Jiyoung ,  LEE, David Kangseong ,  KWAK, Daeyoung ,  PARK, Sohee

IPC分类号： F24F3/16 ,  F24F13/28 ,  F24F13/20

摘要： An air purifying system may include at least three air cleaners or purifiers capable of independently operating and a docking station to support the at least three air purifiers. Since the air purifiers may be separated or stacked together on the docking station, the air purifying system may be operated in various states desired by a user.

公开(公告)号：EP3712514A1

公开(公告)日：2020-09-23

申请号：EP20164348.3

申请日：2020-03-19

申请人： LG Electronics Inc. ,  Chung Ang University Industry Academic Cooperation Foundation

发明人： KANG, Jiyoung ,  CHUNG, Haeyoong ,  JEON, Jongkeon ,  LEE, David Kangseong ,  KWAK, Daeyoung ,  PARK, Sohee

IPC分类号： F24F1/0071 ,  A47L9/28 ,  F24F3/16 ,  F24F11/30 ,  F24F11/89

摘要： An air purifying system includes a robot cleaner configured to generate map information during vacuum cleaning and at least one air purifier that is operated based on the generated map information. Air purifying is performed using updated map information acquired by the robot cleaner during cleaning. The at least one air purifier includes two portable air purifiers mounted on a base air purifier. The two portable air purifiers are configured to be lifted from the base air purifier and moved to separate indoor rooms. The base air purifier includes a controller that determines, based on the generated map information and other information, which rooms the two portable air purifiers should be placed in so that air purifying may be efficient.

公开(公告)号：EP2995300B1

公开(公告)日：2020-04-22

申请号：EP13875242.3

申请日：2013-12-19

申请人： Chung-Ang University Industry-Academic Cooperation Foundation

发明人： LEE, Kangseok ,  BAE, Jeehyeon ,  SEONG, Maeng Je ,  HAN, Min Su ,  YEOM, Ji Hyun ,  RYOU, Sang Mi ,  HA, Nam Chul

IPC分类号： A61K47/54 ,  A61K47/69 ,  A61P35/00 ,  A61K38/00 ,  C12N15/115

公开(公告)号：EP3184639A1

公开(公告)日：2017-06-28

申请号：EP14900237.0

申请日：2014-12-30

申请人： Chung-Ang University Industry-Academy Cooperation Foundation

发明人： KANG, Hyun Ah ,  MOON, Hye Yun ,  KIM, Hong Jin

IPC分类号： C12N15/70 ,  C12N1/19 ,  C12R1/865 ,  A61K39/00

CPC分类号： C12N15/81 ,  A61K9/0053 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/523 ,  A61K2039/54 ,  C07K14/005 ,  C12N15/70 ,  C12N2770/30022 ,  C12N2770/30034 ,  C12N2770/30071 ,  C12R1/865

摘要： The present invention relates to a ribosomal DNA nontranscribed spacer (rDNA NTS)-based gene multiple insertion cassette set and a GRAS-grade recombinant yeast strain using the same. In particular, a gene multiple insertion cassette set including rDNA NTS fragments and an auxotrophic selection marker having an incomplete promoter is developed, and a safe oral recombinant strain having no antibiotic resistant marker is constructed by multiple insertion of an optimum number of the developed gene multiple insertion cassette sets into chromosomes of a Saccharomyces cerevisiae strain. In addition, the present invention provides a vaccine composition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or nodavirus capsid protein (NNVcp) isolated and purified therefrom. In addition, the present invention provides a composition for feed addition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or squalene or oxidosqualene isolated and purified therefrom. Furthermore, the present invention provides a technique of preparing a GRAS-grade recombinant yeast strain for mass production of various recombinant proteins or useful metabolites.

摘要翻译： 本发明涉及基于核糖体DNA非转录间隔区（rDNA NTS）的基因多重插入盒组和使用其的GRAS级重组酵母株。 特别地，开发了包含rDNA NTS片段的基因多重插入盒组和具有不完全启动子的营养缺陷型选择标记，并且通过多次插入最适数量的显现基因倍数构建不具有抗生素抗性标记的安全口服重组菌株 插入盒置于酿酒酵母菌株的染色体中。 此外，本发明提供了一种疫苗组合物，其包含从其分离和纯化的上述菌株，其培养产物，细胞裂解物或诺达病毒衣壳蛋白（NNVcp）作为活性成分。 此外，本发明提供了一种用于饲料添加的组合物，其包含作为活性成分的上述菌株，其培养产物，细胞裂解物或由其分离和纯化的角鲨烯或氧化角鲨烯。 此外，本发明提供了制备用于大量生产各种重组蛋白质或有用代谢物的GRAS级重组酵母菌株的技术。

公开(公告)号：EP2382989A1

公开(公告)日：2011-11-02

申请号：EP11163914.2

申请日：2011-04-27

申请人： Chung-Ang University Industry-Academy Cooperation Foundation

发明人： Kim, Won Yong ,  Chung, In Sik ,  Kim, Jong-Bum ,  Shon, Dong-Hwa ,  Than, Van Thai ,  Yoon, Jang Won ,  Park, Joo Hyoung ,  Baek, In-Hyuk

IPC分类号： A61K39/29 ,  A61K39/15 ,  C07K14/10 ,  C07K14/14

CPC分类号： A61K39/29 ,  A61K39/12 ,  A61K39/15 ,  A61K2039/5256 ,  A61K2039/5258 ,  A61K2039/55566 ,  A61K2039/627 ,  A61K2039/64 ,  C07K14/005 ,  C07K2319/00 ,  C12N2710/14143 ,  C12N2720/12322 ,  C12N2720/12334 ,  C12N2770/32234 ,  C12N2770/32422 ,  C12N2770/32434 ,  G01N33/56983 ,  G01N2333/14 ,  Y02A50/464

摘要： Disclosed are a construct for expressing a rotavirus antigen complex loaded with a heterologous virus epitope, a vaccine composition containing the rotavirus antigen complex, a virus-like particle of rotavirus containing the rotavirus antigen complex, and a vaccine composition containing the virus-like particle of rotavirus. According to the present disclosure, an antigen complex containing a rotavirus antigen as well as a heterologous virus epitope and a virus-like particle of rotavirus containing the antigen complex can be produced in large scale at low cost. Thus, the present disclosure may be applied for research and development of novel complex vaccines for rotavirus and heterologous virus.

摘要翻译： 本发明公开了用于表达载有异源病毒表位，疫苗组合物包含的轮状病毒抗原复合物，含有该轮状病毒抗原复合轮状病毒的病毒样颗粒，以及含有的病毒样颗粒的疫苗组合物中的轮状病毒抗原复合物的构建体 轮状病毒。 。根据本公开，对抗原复合物含一个轮状病毒抗原以及异源病毒的表位和包含抗原复合轮状病毒的病毒样颗粒可以在大规模低成本地制造。 因此，本发明可以应用于研究和轮状病毒复杂和异源病毒的新型疫苗的发展。

公开(公告)号：EP1566007A4

公开(公告)日：2009-07-22

申请号：EP02808184

申请日：2002-11-29

申请人： KOREA ELECTRONICS TELECOMM ,  CHUNG ANG UNIVERSITY

发明人： KIM KWANG-SOON ,  CHANG KYUNG-HI ,  CHO YONG-SOO ,  KIM TAE-GON

IPC分类号： H04B7/26 ,  H04L27/26 ,  H04L7/00

CPC分类号： H04L27/2656 ,  H04L5/0023 ,  H04L5/0048 ,  H04L5/0053 ,  H04L27/2613 ,  H04L27/2657 ,  H04L27/2662 ,  H04L27/2678

摘要： In an OFDMA-based cellular system, a frame of a downlink signal includes a common slot and traffic slots. The common slot includes a synchronization preamble and a cell search preamble. The synchronization preamble has a structure for synchronizing time and frequency, and the cell search preamble has a cell search structure. The traffic slot includes pilot symbols provided on the time and frequency axes. A cyclic prefix is used to estimate initial symbol synchronization, and the initial symbol synchronization and the synchronization preamble are used to synchronize the frame. The synchronization frame and the cell search preamble are used to estimate time and frequency synchronization. The cell search preamble is used to search cells. When the initial synchronization is performed, the cyclic prefix is used to track the frequency, the synchronization preamble is used to track symbol synchronization, and the cell search preamble is used to track fine frequency synchronization.

公开(公告)号：EP1566007A1

公开(公告)日：2005-08-24

申请号：EP02808184.2

申请日：2002-11-29

申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE ,  CHUNG-ANG UNIVERSITY

发明人： KIM, Kwang-Soon,Hana Apt. 109-1203 ,  CHANG, Kyung-Hi,Clover Apt. 104-1409 ,  CHO, Yong-Soo,Shinbanpo Apt. 25-1006 ,  KIM, Tae-Gon,679 Sangdo 1-dong

IPC分类号： H04L7/00

CPC分类号： H04L27/2656 ,  H04L5/0023 ,  H04L5/0048 ,  H04L5/0053 ,  H04L27/2613 ,  H04L27/2657 ,  H04L27/2662 ,  H04L27/2678

摘要： In an OFDMA-based cellular system, a frame of a downlink signal includes a common slot and traffic slots. The common slot includes a synchronization preamble and a cell search preamble. The synchronization preamble has a structure for synchronizing time and frequency, and the cell search preamble has a cell search structure. The traffic slot includes pilot symbols provided on the time and frequency axes. A cyclic prefix is used to estimate initial symbol synchronization, and the initial symbol synchronization and the synchronization preamble are used to synchronize the frame. The synchronization frame and the cell search preamble are used to estimate time and frequency synchronization. The cell search preamble is used to search cells. When the initial synchronization is performed, the cyclic prefix is used to track the frequency, the synchronization preamble is used to track symbol synchronization, and the cell search preamble is used to track fine frequency synchronization.

公开(公告)号：EP3546428A1

公开(公告)日：2019-10-02

申请号：EP18849998.2

申请日：2018-08-28

申请人： LG Chem, Ltd. ,  Chung Ang University Industry Academic Cooperation Foundation

发明人： SUNG, Da Young ,  KIM, Myung Gil ,  JANG, Minchul ,  HWANG, Hyewon

IPC分类号： C01G51/00 ,  C01B21/082 ,  C01B21/097 ,  H01M4/36 ,  H01M4/62 ,  H01M4/587 ,  H01M10/052

摘要： A method for preparing a negative electrode active material, a negative electrode active material prepared using the same, and a lithium secondary battery, and in particular, to a method for preparing a negative electrode active material including the steps of (a) preparing a coating composition including a precursor of metal-phosphorous-oxynitride; (b) forming a precursor layer on a negative electrode active material with the coating composition of (a) using a solution process; and (c) forming a metal-phosphorous-oxynitride protective layer on the negative electrode active material by heat treating the negative electrode active material having the precursor layer formed thereon. The method for preparing a negative electrode active material uses a solution process, which is advantageous in terms of simplifying the whole process and reducing costs, and high capacity, high stabilization and long lifetime are obtained as well by the formed protective layer having excellent properties.