摘要:
The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral activity against picornavirus such as coxsackievirus, enterovirus, echovirus, poliovirus and rhinovirus, and thus can be effectively used as a pharmaceutical composition for the prevention or treatment of viral diseases such as infantile paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myitis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinus infection, or otitis media.
摘要:
Disclosed is an electrolyte for a battery comprising: (a) an electrolyte salt; (b) an organic solvent; and (c) a functional electrolyte additive. An electrochemical device comprising the electrolyte is also disclosed. The additive used in the electrochemical device effectively controls the surface of a cathode active material, which otherwise causes side reactions with an electrolyte, due to the basic skeleton structure and polar side branches of the additive. Therefore, it is possible to improve the safety of a battery, while not adversely affecting the quality of a battery.
摘要:
The present invention relates to 1,3-dioxoindene derivatives, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient with antiviral activity. The 1,3-dioxoindene derivatives of formula (1) according to the present invention have low cyto-toxicity, and can also demonstrate utility as pharmaceutical compositions for preventing or treating viral diseases such as:; polio, viral paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-mouth disease, blistering diseases, hepatitis A, myositis, myocarditis, pancreatitis, viral diabetes, epidemic myalgia, encephalitis, flu, herpes angina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis, otitis media, and the like, since excellent antiviral activity against picornaviruses such as Coxsackie virus, enterovirus, echovirus, polio virus, rhinovirus, and the like, have been demonstrated.
摘要:
The present invention relates to a process of preparing of a phosphorus-containing phosphorus-alumina support by a sol-gel method and a cobalt/phosphorus-alumina catalyst where cobalt is supported onto the phosphorus-alumina support as an active ingredient. The phosphorus-alumina support is prepared by a sol-gel method and has wide specific surface area with bimodal pore size distribution and high cobalt dispersion, thereby enabling to increase heat and mass transfer, stabilize the structure by modifying the surface property of alumina and decrease the deactivation rate due to the reduced oxidation of cobalt component during the F-T reaction. When Fischer-Tropsch reaction (F-T) is conducted on the catalyst, the catalyst maintains a superior thermal stability, inhibits the deactivation due to water generation during the F-T reaction and also causes relatively high conversion of carbon monoxide and stable selectivity of liquid hydrocarbons.
摘要:
The present invention relates to a flaky α-alumina crystal and a preparation method thereof. More particularly, the present invention relates to a flaky α-alumina crystal comprising aluminum oxide and zinc oxide, which is prepared by hydrolyzing an aluminum precursor solution containing a water-soluble flux and a zinc precursor solution to obtain a gel mixture and aging, drying, calcining and crystallizing it under a specific reaction condition, and a preparation method thereof. Since the flaky α-alumina crystal of the present invention has a thickness of less than 0.5 μm, an average particle diameter of at least 15 μm and an aspect ratio of at least 50, it is useful as high-quality pearlescent pigment material and filler for ceramic materials.
摘要:
The present invention relates to a methanol synthesis method using a synthesis gas generated by a mixed reforming of natural gas and carbon dioxide. More particularly, the method of the present invention seeks to utilize carbon dioxide in an economically advantageous manner, and firstly produces a synthesis gas by using a catalyst (Ni/Ce/MgAlO x , or Ni/Ce-Zr/MgAlO x ) and a reaction process condition under which carbon monoxide, carbon dioxide, and hydrogen maintain a specific ratio [H 2 /(2CO+3CO 2 ) = 0.85-1.15] from the mixed reforming wherein the steam reforming of natural gas and the carbon dioxide reforming of methane are carried out at the same time. Subsequently, the thus-produced synthesis gas is employed to synthesize methanol using a catalyst system (the catalyst consisting of a Cu-Zn-Al-based oxide containing CuO, ZnO, and Al 2 O 3 at a predetermined ratio, and cerium-zirconium oxide produced by a sol-gel method) which is appropriate for a methanol synthesis while producing less by-products. Further, the present invention relates to a methanol synthesis method using carbon dioxide in which the synthesis gas which is the unreacted material remaining after the completion of said reforming, is efficiently recirculated and reused to improve the carbon use efficiency (methane and CO 2 use efficiency) of the whole process as well as energy efficiency.