公开(公告)号：EP1424942B1

公开(公告)日：2008-12-31

申请号：EP02796399.0

申请日：2002-08-22

申请人： Montana State University-Bozeman

发明人： NICKEL, Eric, c/o Montana State University-Bozeman ,  SPANGLER, C. W., Montana State University-Bozeman ,  REBANE, A., c/o Montana State University-Bozeman

IPC分类号： A61K41/00 ,  A61P35/00

CPC分类号： A61K41/008 ,  A61B2017/22087

摘要： A method of increasing the multi-photon absorption cross-section of a porphyrin-based photosensitizer by attaching at least one TPA-chromophore at the meso- or beta-positions of a porphyrin structure of the porphyrin-based photosensitizer, and at least one intersystem crossing enhancing substituent to meso- or beta-positions of a porphyrin structure of the porphyrin-based photosensitizer, to thereby increase multi-photon absorption cross-section of the porphyrin-based photosensitizer to at least about 30 GM units at about its maximum wavelength for two-photon absorption. The TPA-chromophore is selected from a group of p-conjugated structures. The resulting porphyrin-based photosensitizer absorbs two photons of radiation in the range of about 700 nm to about 1300 nm. (Figure 2) discloses the molecular structures of three porphyrins.

公开(公告)号：EP1590698A2

公开(公告)日：2005-11-02

申请号：EP04705220.4

申请日：2004-01-26

申请人： Montana State University-Bozeman

发明人： HIMMER, P. A. ,  DICKENSHEETS, David L.

IPC分类号： G02B26/08

CPC分类号： G02B26/06 ,  G02B26/0825

摘要： An optical element (Fig. 1) with multi-layer composites(12, 14, 16, 18) that deforms to reduce optical aberrations in off-axis optic. Methods are also described in relation to the optical element.

公开(公告)号：EP1438256A2

公开(公告)日：2004-07-21

申请号：EP02780484.8

申请日：2002-10-21

申请人： Montana State University-Bozeman

发明人： DICKENSHEETS, David L. ,  KAISER, Todd J. ,  HIMMER, Philip A. ,  LUTZENBERGER, Jeffrey ,  FRIHOLM, Robert A.

IPC分类号： B81B3/00

CPC分类号： B81B3/007

摘要： Stiffened surface micromachined structures and a method to fabricate the same. A silicon substrate (10) is first etched to produce a mold containing a plurality of trenches or grooves (14) in a lattice configuration. Sacrificial oxide (15) is then grown on the silicon substrate (10) and then a stiffening member (16) (silicon nitride) is deposited over the surface of the substrate, thereby backfilling the grooves with silicon nitride. The silicon nitride is patterned to form mechanical members and metal (40) is then deposited and patterned to form the leads and capacitors for electrostatic actuation of mechanical members. The underlying silicon and sacrificial oxides are removed by etching the mold from underneath the fabricated micromachined devices, leaving free-standing silicon nitride devices with vertical ribs. The devices exhibit increased out-of-plan bending stiffness because of the presence of stiffening ribs. Silicon nitride biaxial pointing mirrors with stiffening ribs are also described.

公开(公告)号：EP1424942A1

公开(公告)日：2004-06-09

申请号：EP02796399.0

申请日：2002-08-22

申请人： Montana State University-Bozeman

发明人： NICKEL, Eric,c/o Montana State University-Bozeman ,  SPANGLER, C. W.,Montana State University-Bozeman ,  REBANE, A.,c/o Montana State University-Bozeman

IPC分类号： A61B10/00 ,  A61B5/00 ,  A61B8/00

CPC分类号： A61K41/008 ,  A61B2017/22087

摘要： A method of increasing the multi-photon absorption cross-section of a porphyrin-based photosensitizer by attaching at least one TPA-chromophore at the meso- or beta-positions of a porphyrin structure of the porphyrin-based photosensitizer, and at least one intersystem crossing enhancing substituent to meso- or beta-positions of a porphyrin structure of the porphyrin-based photosensitizer, to thereby increase multi-photon absorption cross-section of the porphyrin-based photosensitizer to at least about 30 GM units at about its maximum wavelength for two-photon absorption. The TPA-chromophore is selected from a group of p-conjugated structures. The resulting porphyrin-based photosensitizer absorbs two photons of radiation in the range of about 700 nm to about 1300 nm. (Figure 2) discloses the molecular structures of three porphyrins.

公开(公告)号：EP0994961B1

公开(公告)日：2006-10-18

申请号：EP98932782.0

申请日：1998-06-17

申请人： Montana State University - Bozeman ,  UNIVERSITY OF IOWA RESEARCH FOUNDATION ,  THE UNIVERSITY OF ROCHESTER

发明人： DAVIES, David, G. ,  COSTERTON, John, William ,  PARSEK, Matthew, R. ,  GREENBERG, Everett, P. ,  PEARSON, James, P. ,  IGLEWSKI, Barbara, H.

IPC分类号： A01N43/08 ,  A61K31/365

CPC分类号： C02F1/50 ,  A01N43/08 ,  A01N2300/00

摘要： A method to control the formulation, persistence and dispersion of microbial biofilms by taking advantage of the natural process of cell-cell communication in bacteria. Addition of N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL) and N-butyryl-L-homoserine lactone (BHL) either in combination or separately or the addition of chemicals which will enhance or inhibit the activity of OdDHL and BHL can inhibit the formation, persistence or dispersion of bacterial and algal biofilms, in industrial, medical and environmental situations.

公开(公告)号：EP1604230A2

公开(公告)日：2005-12-14

申请号：EP04775822.2

申请日：2004-03-03

申请人： Montana State University-Bozeman

发明人： DICKENSHEETS, David, L.

IPC分类号： G02B1/00

CPC分类号： G02B21/0048 ,  A61B5/0068 ,  A61B5/0084 ,  A61B5/745 ,  G02B21/0028 ,  G02B26/0825

摘要： A confocal optical device (10) is described. The device includes a tri-axial scanning mirror (48a) that can provide for three-dimensional scanning of objects. In particular, the scanning mirror (48a) has a deformable reflective membrane (48h) mounted on two annular gimbaled members (48c, 48d) to provide for rotation about two orthogonal axes. The deformable membrane, which can be provided at other suitable locations in the device, is used to control the focusing spot of the light beam transmitted from the device to the object being scanned. Various methods relating to the confocal optical device are also described.

公开(公告)号：EP1487269A1

公开(公告)日：2004-12-22

申请号：EP03714161.1

申请日：2003-03-13

申请人： Montana State University-Bozeman

发明人： LIVINGHOUSE, Tom

IPC分类号： A01N43/08 ,  A01N37/28 ,  C07D307/26 ,  C07D333/04

CPC分类号： C07D307/33 ,  C07D307/26 ,  C07D307/32

摘要： Autoinducer compounds which enhance gene expression in a wide variety of microorganisms, therapeutic compositions and therapeutic methods wherein gene expression within microorganisms is regulated are disclosed.

公开(公告)号：EP2911519A2

公开(公告)日：2015-09-02

申请号：EP13848736.8

申请日：2013-10-23

申请人： Montana State University-Bozeman

发明人： GIROUX, Michael

IPC分类号： A21D2/00 ,  A23L1/05

CPC分类号： A23L7/198 ,  A01H5/10 ,  A23L7/10 ,  A23L7/109 ,  A23L29/212 ,  A23L33/21 ,  C07K14/415 ,  C12N15/8245

摘要： The present invention provides compositions and methods of altering/improving Durum wheat phenotypes. Furthermore, methods of breeding Durum wheat and/or other closely related species to produce plants having altered or improved phenotypes are provided.

公开(公告)号：EP2897638A1

公开(公告)日：2015-07-29

申请号：EP13771738.5

申请日：2013-09-24

申请人： Montana State University-Bozeman

发明人： PASCUAL, David W. ,  MADDALONI, Massimo

IPC分类号： A61K39/108 ,  A61K35/74 ,  A61P37/06

CPC分类号： A61K39/0258 ,  A23L33/135 ,  A23V2002/00 ,  A61K35/744 ,  A61K35/747 ,  A61K2039/523 ,  A61K2039/58 ,  Y02A50/474

摘要： The present disclosure relates generally to therapeutic compositions comprising recombinant bacteria. Further, the disclosure elaborates upon methods of utilizing the taught therapeutic compositions to treat autoimmune and inflammatory disease. The present teachings also relate to the disclosed recombinant bacteria and methods of producing the recombinant bacteria utilized in the compositions and methods. Further taught herein are dietary supplements and food additive compositions comprising the taught recombinant bacteria.

公开(公告)号：EP1575419B1

公开(公告)日：2015-05-27

申请号：EP03786898.1

申请日：2003-12-10

申请人： Duke University ,  Montana State University-Bozeman

发明人： STAMLER, Jonathan, S. ,  SINGEL, David, J.

IPC分类号： C07K14/805

CPC分类号： C07K14/805