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    APPARATUS USING A LASER LUCENT NEEDLE
    4.
    发明授权
    APPARATUS USING A LASER LUCENT NEEDLE 失效
    - 激光半透明针装置

    公开(公告)号：EP0582686B1

    公开(公告)日：1998-08-12

    申请号：EP92917323.5

    申请日：1992-03-24

    申请人： INDIGO MEDICAL, INCORPORATED

    发明人： CONN, Richard, L. ,  LOREE, Thomas, Robert ,  BIGIO, Irving, Joseph ,  STROBL, Karlheinz

    IPC分类号： A61N5/06 ,  A61B17/36 ,  G02B6/00

    CPC分类号： A61N5/062 ,  A61B18/22 ,  A61B2017/22072 ,  A61B2017/22087 ,  A61B2018/00011 ,  A61B2018/2261 ,  A61N5/0601 ,  A61N2005/067

    摘要： Apparatus formed of a laser lucent hollow, transparent needle (10) with an optical fiber (12) disposed within its interior. Means such as a spacer (14) can be used to retain the fiber in position within the needle. In a particular embodiment, the end of the needle adjacent to the energy transmitting end of the fiber is closed, and energy scatterers or diffusers (18) may be provided to alter the characteristics of the transmitted energy. In further embodiments, scattering or diffusing materials (32) are disposed within the walls and the closed end (16) of the needle to form a laser lucent apparatus customized to specific hyperthermia requirements. In other embodiments, the needle is open-ended for insertion of a specialized instrument for such uses as biopsies and spectroscopic tissue analyses. These procedures can be conducted before or after hyperthermia treatment of the tissue by replacing fiber in the needle casing with such a specialized instrument or vice-versa. A particular application facilitates the use of laser-induced hyperthermia to treat benign prostatic hypertrophy.

    MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE
    10.
    发明公开
    MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE 有权
    药物化学治疗疾病的治疗

    公开(公告)号：EP1311261A1

    公开(公告)日：2003-05-21

    申请号：EP01954627.4

    申请日：2001-07-10

    申请人： Photogen, Inc.

    发明人： DEES, H., Craig ,  SCOTT, Timothy

    IPC分类号： A61K31/352

    CPC分类号： A61K41/0057 ,  A61B2017/22062 ,  A61B2017/22087 ,  A61F7/00 ,  A61K9/0014 ,  A61K9/0019 ,  A61K31/352 ,  A61K41/0071 ,  A61K47/10 ,  A61K47/12 ,  A61K47/20 ,  A61N5/0601 ,  A61N5/062 ,  C07D311/82 ,  Y02A50/473 ,  Y10T436/193333

    摘要： New chemotherapeutic medicaments and certain medical uses and methods for use of such chemotherapeutic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. Preferably, the halogenated xanthene is Rose Bengal or a functional derivative of Rose Bengal. The halogenated xanthenes constitute a family of useful chemotherapeutic agents that afford selective, persistent accumulation in certain tissues. In preferred embodiments, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another preferred embodiment, such medicaments are produced in various formulations useful for intracorporeal or topical administration, including in liquid, semisolid, solid or aerosol delivery vehicles.