公开(公告)号：EP2948126A4

公开(公告)日：2016-11-02

申请号：EP14743761

申请日：2014-01-24

申请人： OTAGO INNOVATION LTD

发明人： MELEDANDRI CARLA JOY ,  SCHWASS DONALD ROYDEN

IPC分类号： A61K33/38 ,  A61K6/00 ,  A61K9/10 ,  A61K9/14 ,  A61K47/20 ,  A61P31/04

CPC分类号： A61K33/38 ,  A61C19/06 ,  A61K9/0063 ,  A61K9/1075 ,  A61K9/14 ,  A61K47/20 ,  A61N1/205 ,  A61N1/30

摘要： An assembly of micelle aggregates, wherein each aggregate comprises micelles of an anionic surfactant and nano-sized particles of metallic silver. A product comprising such assemblies for use in treating or preventing bacterial infections.

公开(公告)号：EP2849774A4

公开(公告)日：2015-11-25

申请号：EP13790791

申请日：2013-05-17

申请人： OTAGO INNOVATION LTD

发明人： WISE LYN MARIE ,  FLEMING STEPFEN BRUCE ,  MERCER ANDREW ALLAN

IPC分类号： A61K38/16 ,  A61K9/06 ,  A61K9/107 ,  A61K38/18 ,  A61K38/20 ,  A61P17/02

CPC分类号： A61K38/1866 ,  A61K9/06 ,  A61K38/2066 ,  A61K2300/00

摘要： Viral VEGF and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

公开(公告)号：EP2029745A4

公开(公告)日：2009-12-16

申请号：EP07808640

申请日：2007-06-07

申请人： OTAGO INNOVATION LTD

发明人： ASSINDER STEPHEN JOHN ,  STANTON JO-ANN

IPC分类号： C12N15/11 ,  A61B5/00 ,  C12Q1/00

CPC分类号： C07K14/4748 ,  C12Q1/6816 ,  C12Q1/6886 ,  G01N33/5023 ,  G01N33/57434 ,  G01N2500/00 ,  G01N2800/52 ,  C12Q2543/101

公开(公告)号：EP1929015A4

公开(公告)日：2009-02-25

申请号：EP06799576

申请日：2006-08-30

申请人： OTAGO INNOVATION LTD

发明人： CARDNO TONY STUART ,  TATE WARREN PERRY

IPC分类号： C12N15/62 ,  C12Q1/68

CPC分类号： C12N15/62 ,  C07K14/43595 ,  C07K2319/60 ,  C12N15/10

摘要： The invention relates to a translational recoding reporter construct comprising: a first fluorescent protein coding sequence; a second fluorescent protein coding sequence encoding a fluorescent protein different from the first fluorescent protein; and a linker sequence interposed between the first and second fluorescent protein coding sequence; wherein the a first fluorescent protein coding sequence and the second fluorescent protein coding sequence are out-of-frame with respect to each other but are co-expressed as a single fusion polypetpdie upon recoding. The invention also relates to methods of use of the construct in screening modulators of recoding.

公开(公告)号：EP3011337A4

公开(公告)日：2016-12-21

申请号：EP14813075

申请日：2014-06-20

申请人： OTAGO INNOVATION LTD

发明人： MCLENNAN IAN STUART ,  PANKHURST MICHAEL WILLIAM

IPC分类号： G01N33/53

CPC分类号： G01N33/74

公开(公告)号：EP2825865A4

公开(公告)日：2016-04-06

申请号：EP13757679

申请日：2013-03-08

申请人： OTAGO INNOVATION LTD

发明人： RAWLE CHRISTOPHER BRUCE

IPC分类号： G01N27/10 ,  B01L7/00 ,  B01L9/06 ,  C12Q1/68 ,  C12Q1/70 ,  G01N21/03 ,  G01N21/15 ,  G01N21/64 ,  G02B27/14 ,  H01L35/00 ,  H05B1/00 ,  H05B3/00

CPC分类号： G01N21/6452 ,  B01L7/52 ,  B01L9/06 ,  B01L2300/0654 ,  C12Q1/686 ,  C12Q1/689 ,  C12Q1/701 ,  G01N21/0332 ,  G01N21/6486 ,  G01N2021/158 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6463 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/068 ,  G02B27/146

摘要： An optical assembly 140 for a portable device for detecting molecule(s) within reaction vessels 110 comprises a collimator 403, a beam splitter arrangement and a plurality of guide arrangements 143. The collimator 403 collimates an excitation beam from an excitation source 400. The beam splitter arrangement splits the excitation beam from the collimator into a plurality of split excitation beams. Each beam splitter splits an incoming beam into two beams. In the case where the beam splitter arrangement comprises more than one beam splitter, the beam splitters are arranged in tiers such that a first tier comprises one beam splitter for receiving the excitation beam from the collimator, and each of the other tiers comprises one or more beam splitters. Each beam splitter in at least one of the other tiers receives a split excitation beam from a previous tier. Each guide arrangement 140 guides a respective one of the plurality of split excitation beams along an excitation path A from the beam splitter arrangement into a reaction vessel 110 containing a sample to stimulate an emission of a reaction light from the sample. Each guide arrangement 140 further guides reaction light from the sample along a detection path B towards a detector arrangement 142.

公开(公告)号：EP2263086A4

公开(公告)日：2012-10-17

申请号：EP09713096

申请日：2009-02-20

申请人： OTAGO INNOVATION LTD

发明人： PEMBERTON CHRISTOPHER JOSEPH ,  RICHARDS ARTHUR MARK ,  NICHOLLS MICHAEL GARY ,  YANDLE TIMOTHY GRANT

IPC分类号： G01N33/53 ,  C07K7/06 ,  C07K16/26 ,  G01N33/68

CPC分类号： C07K16/26

公开(公告)号：EP2265641A4

公开(公告)日：2012-08-01

申请号：EP09719459

申请日：2009-03-12

申请人： OTAGO INNOVATION LTD

发明人： PEMBERTON CHRISTOPHER JOSEPH ,  RICHARDS ARTHUR MARK ,  NICHOLLS MICHAEL GARY ,  YANDLE TIMOTHY GRANT

IPC分类号： C07K16/18 ,  C07H21/04 ,  C07K7/06 ,  C12N15/12 ,  G01N33/487 ,  G01N33/53

CPC分类号： C07H21/04 ,  C07K14/62 ,  C07K16/18 ,  G01N33/6893 ,  G01N33/74 ,  G01N2333/62 ,  G01N2800/042 ,  G01N2800/324 ,  G01N2800/50

摘要： The invention provides binding agents and assays tor insulin signal peptide. The agents and assays are useful in methods tor predicting, diagnosing, assessing or monitoring acute cardiac disorders, glucose handling disorders and diabetes in a subject. Also provided are nucleotides, polypeptides, and kits useful in the methods of the invention.

摘要翻译： 本发明提供了胰岛素信号肽的结合剂和测定法。 这些试剂和测定法可用于预测，诊断，评估或监测受试者中急性心脏病，葡萄糖治疗障碍和糖尿病的方法。 还提供了可用于本发明方法的核苷酸，多肽和试剂盒。

公开(公告)号：EP1940450A4

公开(公告)日：2010-12-29

申请号：EP06812850

申请日：2006-10-26

申请人： OTAGO INNOVATION LTD

发明人： MCLENNAN IAN STUART ,  KOISHI KYOKO ,  WANG PEI-YU

IPC分类号： A61K38/18 ,  A61K38/27 ,  A61P25/00 ,  G01N33/53

CPC分类号： G01N33/6896 ,  A61K31/198 ,  A61K31/565 ,  A61K31/568 ,  A61K31/57 ,  A61K38/185 ,  A61K38/22 ,  G01N2500/04 ,  G01N2800/2814 ,  A61K2300/00

公开(公告)号：EP2828282A4

公开(公告)日：2015-08-26

申请号：EP13764431

申请日：2013-03-15

申请人： OTAGO INNOVATION LTD

发明人： PEMBERTON CHRISTOPHER JOSEPH ,  RICHARDS ARTHUR MARK ,  BYERS MATHEW SIMON

IPC分类号： C07K7/06 ,  C07K14/63 ,  C12Q1/68 ,  G01N33/68 ,  G01N33/74

CPC分类号： G01N33/74 ,  C07K14/575 ,  C07K14/63 ,  C07K16/26 ,  G01N33/6893 ,  G01N2800/12 ,  G01N2800/325

摘要： Ghrelin signal peptide fragment assays and kits useful in the diagnosis, prognosis, risk stratification, assessing, staging, monitoring, categorizing and determination of further diagnoses and treatment regimens in subjects with various disorders, diseases and conditions including, pneumonia, heart failure, or pneumonia and heart failure or suspected pneumonia, heart failure, or pneumonia and heart failure, and methods for monitoring treatment.

摘要翻译： 生长激素释放肽信号肽片段测定和试剂盒可用于各种疾病，疾病和病症（包括肺炎，心力衰竭或肺炎）的受试者的诊断，预后，风险分层，评估，分期，监测，分类和确定其他诊断和治疗方案 心力衰竭或疑似肺炎，心力衰竭，肺炎和心力衰竭以及监测治疗方法。