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    TEST STRIP ANALYSIS APPARATUS
    6.
    发明公开
    TEST STRIP ANALYSIS APPARATUS 审中-公开
    TESTSTREIFENANALYSEVORRICHTUNG

    公开(公告)号：EP1459051A1

    公开(公告)日：2004-09-22

    申请号：EP02789764.4

    申请日：2002-11-18

    申请人： QUIDEL CORPORATION

    发明人： ZIEGLER, Walter

    IPC分类号： G01N21/47 ,  G01N35/00

    CPC分类号： G01N21/8483 ,  G01N35/04 ,  G01N2035/00108 ,  G01N2035/0465 ,  G01N2035/0484 ,  Y10T436/110833 ,  Y10T436/113332

    摘要： A test strip analysis apparatus comprising a housing, an insertion station for receiving a test strip to be inspected, an optical measuring unit for measuring the test strip, a transport device for transporting the test strip from said insertion station to the optical measuring unit within the reaction period required for the test strip, and an analyzing unit for evaluating the measurement of the strip, wherein the transport device comprises first and second transport sections which are interconnected through a connecting region and can be driven independently of one another, with the first transport section being capable of transporting the test strip at a higher first transport speed from the insertion station to the connecting region, and the second transport section being capable of transporting the test strip at a slower second transport speed from the connecting region to the optical measuring unit.

    Assays for Trichomonas vaginalis
    7.
    发明公开
    Assays for Trichomonas vaginalis 审中-公开
    Testverfahren zur Bestimmung von Trichomonas vaginalis

    公开(公告)号：EP1422525A1

    公开(公告)日：2004-05-26

    申请号：EP03256386.8

    申请日：2003-10-09

    申请人： Quidel Corporation

    发明人： Lawrence, Paul J. ,  Hughes, Mark A. ,  Chaudhauri, Aulena ,  Andreason, Terrence J.

    IPC分类号： G01N33/50 ,  G01N33/58 ,  C12Q1/34

    CPC分类号： C12Q1/04 ,  C12Q1/34 ,  G01N33/581 ,  G01N2333/44 ,  G01N2800/26 ,  G01N2800/36

    摘要： The release by trichomonads of a hydrolase that hydrolyzes a narrowly defined class of substrates at a low pH without interference from hydrolases that are unrelated to trichomoniasis is the basis for a selective diagnostic assay for trichomoniasis that measures hydrolysis of any of these substrates by vaginal fluid at a low pH. Selective assays for trichomoniasis are also obtained by removing particulate matter from a sample of vaginal fluid to extract a fraction devoid of particles greater than a selected size, and where desired, combining the extracted fraction with any of certain specified hydrolase inhibitors, then testing the fraction for enzymatic hydrolase activity. These qualities of trichomoniasis are the basis for a series of diagnostic tests and test devices that produce results that are detectable by visual and other means with a high degree of accuracy.

    摘要翻译： 水解酶的释放是在低pH条件下水解狭义定义类型的底物而不受水滑石干扰与毛滴虫病无关的水解酶的释放，是选择性诊断滴滴虫病检测的基础，其通过阴道液体测量任何这些底物的水解 低pH值。 毛滴虫病的选择性检测也可通过从阴道液样品中除去颗粒物以提取不含大于所选大小的颗粒的部分，并且如果需要，将提取的级分与某些特定的水解酶抑制剂中的任何一种组合，然后测试级分 用于酶促水解酶活性。 毛滴虫病的这些质量是一系列诊断测试和测试装置的基础，其产生可以通过视觉和其他方式以高精度检测的结果。

    ANTIGEN-SPECIFIC ONE-STEP ASSAYS
    8.
    发明公开
    ANTIGEN-SPECIFIC ONE-STEP ASSAYS 失效
    抗原特异性一步法

    公开(公告)号：EP0705426A1

    公开(公告)日：1996-04-10

    申请号：EP94920037.0

    申请日：1994-05-24

    申请人： QUIDEL CORPORATION

    发明人： MILLER, Steven, Paul ,  QUIWA, Nol ,  PRONOVOST, Allan, D.

    IPC分类号： G01N33 ,  G01N37

    CPC分类号： G01N33/558 ,  G01N33/6854 ,  G01N33/80 ,  Y02A50/57

    摘要： A method and a device for determining, in a biological fluid sample, levels of antigen-specific immunoglobulins, said device comprising a matrix (1) defining an axial flow path, which matrix (1) has a sample receiving zone (2), a labelling zone (3) comprising a visible label bound to a first immunoglobulin-binding substance, a capture zone (4) comprising an immobilized second immunoglobulin-binding substance, and an absorbent pad (5) located sequentially downstream therein. Application of the sample to the sample receiving zone (2) results in specific binding of immunoglobulin present in the sample to labelling complex and accumulation of any antigen-specific immunoglobulin-labelling complex in the capture zone (4). The device and method are useful in determining allergen-specific IgE or other immunoglobulins specific for pathogens; and, may be used to simultaneously determine a plurality of immunoglobulins specific for different antigens or pathogens.