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51 条记录 (耗时 0.015 秒)

    METER
    1.
    发明授权
    METER 有权
    仪表

    公开(公告)号：EP2085778B1

    公开(公告)日：2017-11-29

    申请号：EP09005911.4

    申请日：1998-12-21

    申请人： Roche Diagnostics Operations, Inc.

    发明人： Beaty, Terry ,  Burke, David W. ,  Kuhn, Lance Scott ,  Svetnik, Vladimir

    IPC分类号： G01N33/487

    CPC分类号： G01N27/3274

    摘要： The invention concerns an apparatus (31, 32, 132) and a corresponding method for determining the concentration of a medically significant component of a biological fluid, the apparatus comprising a cell (31) for receiving a sample of the fluid and an instrument (32, 132) including an assessment controller (52, 54, 152, 158, 252) for applying a first signal, preferably having an AC component, to the cell, for determining a first response of the cell to the first signal, for determining the identity of the sample in response of the cell to the first signal, and for producing an indication of the identity of the sample.

    Meter
    4.
    发明公开
    Meter 有权
    仪表

    公开(公告)号：EP2085779A1

    公开(公告)日：2009-08-05

    申请号：EP09005912.2

    申请日：1998-12-21

    申请人： Roche Diagnostics Operations, Inc.

    发明人： Beaty, Terry ,  Burke, David W. ,  Kuhn, Lance Scott ,  Svetnik, Vladimir

    IPC分类号： G01N33/487

    CPC分类号： G01N27/3274

    摘要： The invention concerns an apparatus (31, 32, 132) and a corresponding method for determining the concentration of a medically significant component of a biological fluid, the apparatus comprising a cell (31) for receiving a sample of the fluid and an instrument (32, 132) including an assessment controller (52, 54, 152, 158, 252) for applying a first signal, preferably having an AC component, to the cell, for determining a first response of the cell to the first signal, for determining the identity of the sample in response of the cell to the first signal, and for producing an indication of the identity of the sample.

    摘要翻译： 本发明涉及一种用于确定生物流体的医学上重要组分的浓度的装置（31,32,132）和相应的方法，该装置包括用于接收流体样本的细胞（31）和器械（32 ，132），其包括评估控制器（52,54,152,158,252），用于将优选具有AC分量的第一信号施加到所述单元，用于确定所述单元对所述第一信号的第一响应，用于确定 细胞对第一信号的反应的样本的同一性，以及用于产生样本的身份的指示。

    AMPEROMETRIC BIOSENSOR TEST STRIP
    5.
    发明授权
    AMPEROMETRIC BIOSENSOR TEST STRIP 有权
    TEST条纹FOR A电流计生物传感器

    公开(公告)号：EP1244809B1

    公开(公告)日：2007-01-31

    申请号：EP00989267.0

    申请日：2000-12-14

    申请人： Roche Diagnostics Operations, Inc.

    发明人： WILSEY, Christopher, D. ,  BURKE, David, W.

    IPC分类号： C12Q1/00 ,  C12Q1/32

    CPC分类号： C12Q1/005 ,  Y10S435/817

    摘要： A reagent and method for determining the levels of 3-hydroxybutyric acid in a sample are provided. The reagent comprises a ferricyanide salt, a catalytic amount of a first enzyme operative to catalyze the oxidation of 3-hydroxybutyric acid in the sample, a cofactor corresponding to said first enzyme, and a catalytic amount of a second enzyme operative to catalyze the oxidization of the cofactor and the reduction of the ferricyanide. The reagent is incorporated into a test strip that generates an electrical output signal indicative of the level of 3-hydroxybutyric acid when the reagent is contacted with a sample.

    EVANESCENT WAVE IMMUNOASSAY SYSTEM
    7.
    发明授权
    EVANESCENT WAVE IMMUNOASSAY SYSTEM 失效
    与渐逝波免疫

    公开(公告)号：EP0815431B1

    公开(公告)日：2006-07-19

    申请号：EP96906213.2

    申请日：1996-01-25

    申请人： Roche Diagnostics Operations, Inc.

    发明人： MESEROL, Peter

    IPC分类号： G01N21/01 ,  G01N21/64 ,  G01N21/03 ,  G01N21/77

    CPC分类号： G01N21/648 ,  G01N21/6428 ,  G01N21/7703

    摘要： Apparatus for assaying a fluid sample with radiation capable of exciting fluorescence in fluorescent material comprises a totally internally reflecting, unitary elongated substrate (24) transmissive to both the excitation radiation and to the fluorescence. The fluorescent material includes at least a moiety of an antibody-antigen complex that includes a tag that will provide the fluorescence when excited by an evanescent wave generated by the excitation radiation. The substrate (24) includes an elongated fiber (36) and an integral lens (38) formed to guide the optical radiation into the fiber (36) within the bounds of a critical angle to assure total internal reflectance. A hollow elongated enclosure (40) is disposed concentrically about and spaced from the fiber (36) so as to provide an interspace of capillary dimensions. A test implement (22) supports the elongated substrate (24), has a reservoir (28) for receiving a fluid sample to be assayed, and is selectively movable to an operative position whereat the fluid sample is caused to flow onto the fiber (36) and, by capillary action, into the interspace between the fiber (36) and the enclosure (40). The apparatus further includes a source of the excitation radiation (74), refractive means (38) for focusing the radiation toward the lens (38), detector means (78) for detecting fluorescence radiation emitted from an end of the fiber (36) responsively to the excitation radiation, and optics frame means (66) for mounting all components in fixed relation to the lens (38) for introducing the excitation radiation into the lens (38) within the critical angle.