公开(公告)号：EP3228709A4

公开(公告)日：2018-06-20

申请号：EP15865944

申请日：2015-11-27

申请人： WAKO PURE CHEM IND LTD ,  UNIV OSAKA

发明人： NISHIBU TAKAHIRO ,  IMAWAKA NAOKO ,  NARUSE KEN ,  HANAYAMA RIKINARI

IPC分类号： C12N15/09 ,  C07K1/14 ,  C07K14/705 ,  C07K17/00 ,  C12N7/02 ,  G01N33/53

CPC分类号： G01N33/5076 ,  C07K1/14 ,  C07K14/70503 ,  C07K17/00 ,  C07K17/02 ,  C07K2319/40 ,  C12N7/02 ,  C12N15/09 ,  G01N33/53 ,  G01N33/5432 ,  G01N33/6842 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/149

摘要： An object of the present invention is to provide a carrier and a method for obtaining or removing extracellular membrane vesicle or virus present in a sample in good purity and in an intact state simply and conveniently, as well as and efficiently, or detecting them in high sensitivity. The present invention relates to: "1. a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; 2. a method for obtaining the extracellular membrane vesicle or the virus in the sample; 3. a method for removing the extracellular membrane vesicle or the virus in the sample; 4. a method for detecting the extracellular membrane vesicle or the virus in the sample; 5. a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and 6. a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier".

公开(公告)号：EP3226340A4

公开(公告)日：2017-10-11

申请号：EP15864065

申请日：2015-11-27

申请人： WAKO PURE CHEM IND LTD

发明人： SATO KAZUHIKO ,  KIYOSU TAKAHIRO ,  MIZUTA HIRONORI ,  MORI GORO ,  OKAMOTO KUNIAKI

IPC分类号： H01M10/0568 ,  C07F7/08 ,  H01M10/054 ,  H01M10/0567

CPC分类号： H01M10/0568 ,  C07F7/0836 ,  C07F19/005 ,  H01M4/381 ,  H01M10/054 ,  H01M10/0567 ,  H01M2300/0025

摘要： It is an object of the present invention to provide an electrolytic solution having high oxidation decomposition potential, where dissolution and deposition of magnesium proceed repeatedly and stably, using a non-nucleophilic alkoxide-type magnesium salt. The present invention relates to (1) an electrolytic solution for a magnesium battery comprising a mixture of a compound represented by the following general formula (I), a Lewis acid and a solvent: (2) an electrochemical device comprising the electrolytic solution, a positive electrode and a negative electrode, and (3) a compound represented by the following general formula (I'):

公开(公告)号：EP3124551A4

公开(公告)日：2017-02-01

申请号：EP15768174

申请日：2015-03-27

申请人： WAKO PURE CHEM IND LTD

发明人： SUZUKI KATSUFUMI ,  HORIE TOMOAKI ,  SHIDA YUKIHIKO

IPC分类号： C09B11/28 ,  C07D311/80 ,  C08F20/36 ,  C08F20/60 ,  C08F220/56 ,  C09B11/24 ,  C09B67/20 ,  C09B69/10

CPC分类号： C09B69/103 ,  C07D311/80 ,  C08F20/36 ,  C08F220/18 ,  C08F220/56 ,  C09B11/24

摘要： A colored resin composition using a conventional rhodamine derivative has not provided heat resistance in a practical range. Therefore, it is an object of the present invention to provide a coloring composition having higher heat resistance as compared with the conventional coloring composition. The present invention relates to a compound represented by the following general formula (1), and a polymer having a monomer unit derived from the compound, and the like. (wherein R 1 to R 4 each independently represent a hydrogen atom, an alkyl group, and the like; R 7 represents a hydrogen atom or a methyl group; R 8 and R 9 each independently represent a hydrogen atom or an alkyl group; Y represents a nitrogen atom or a group represented by the following formula (1-1): A 1 represents an alkylene group which has at least one group selected from -O-, -OCO-, -COO-, -NHCO-, -CONH-, -NHCONH- and an arylene group in the chain, and the like; A 2 represents -NH- or -O-; An - represents an anion containing an aryl group having an electron-withdrawing substituent, and the like; n represents an integer of 0 to 3; R 8 and R 9 may form a cyclic structure of a 5 to 6 membered ring together with -N-(CH 2 ) n -Y bonding thereto.)

摘要翻译： 使用常规罗丹明衍生物的着色树脂组合物在实际范围内不具有耐热性。 因此，本发明的目的是提供与常规着色组合物相比具有较高耐热性的着色组合物。 本发明涉及下述通式（1）所示的化合物和具有来自该化合物的单体单元的聚合物等。 （其中R 1至R 4各自独立地表示氢原子，烷基等; R 7表示氢原子或甲基; R 8和R 9各自独立地表示氢原子或烷基; Y 表示氮原子或由下式（1-1）表示的基团：A 1表示具有选自-O - ， - OCO - ， - COO - ， - NHCO - ， - CONH中的至少一个基团的亚烷基 - ，-NHCONH-和链中的亚芳基等; A 2表示-NH-或-O-; An - 表示含有具有吸电子取代基的芳基的阴离子等; n表示具有吸电子取代基的芳基 0至3的整数; R 8和R 9可以与-N（（CH 2）n -Y键合在一起形成5至6元环的环状结构）。

公开(公告)号：EP2940149A4

公开(公告)日：2016-07-27

申请号：EP13869328

申请日：2013-12-24

申请人： WAKO PURE CHEM IND LTD

发明人： HAYASHIDA YUKINOBU ,  YAMAMOTO NAOYUKI

IPC分类号： C12Q1/68 ,  C12N15/09

CPC分类号： C12Q1/6858 ,  C12Q2537/164 ,  C12Q2563/137

公开(公告)号：EP2910607A4

公开(公告)日：2016-06-15

申请号：EP13846619

申请日：2013-10-15

申请人： WAKO PURE CHEM IND LTD

发明人： FUJITA YOSHIKAZU ,  OHASHI TOSHINARI ,  YAMAMOTO NAOYUKI ,  TAKAGAKI TAKASHI ,  HASABA SATOSHI

IPC分类号： C09B11/28 ,  G01N31/00 ,  G01N31/22 ,  G01N33/52 ,  G01N33/84

CPC分类号： G01N33/84 ,  C09B11/24 ,  C09B11/28 ,  C09B49/12 ,  G01N31/00 ,  G01N31/22 ,  G01N33/20 ,  G01N33/90

公开(公告)号：EP2821498A4

公开(公告)日：2015-12-09

申请号：EP13755221

申请日：2013-02-27

申请人： NAT INST OF ADVANCED IND SCIEN ,  WAKO PURE CHEM IND LTD

发明人： TATENO HIROAKI ,  HIRABAYASHI JUN ,  ASASHIMA MAKOTO ,  ITO YUZURU ,  ONUMA YASUKO ,  WARASHINA MASAKI ,  FUKUDA MASAKAZU

IPC分类号： C12Q1/02 ,  C12M1/00 ,  C12M1/34 ,  C12N5/10 ,  G01N33/569

CPC分类号： G01N33/56966

摘要： Provided are a method for accurately evaluating the differentiation status of stem cells by selectively staining only stem cells in an undifferentiated state, and a method for positively isolating only stem cells in an undifferentiated state. Specifically provided is a method for determining differentiation of a cell comprising a step of contacting a test cell with a probe comprising protein (A) or (B) below and a step of detecting the presence of binding of the probe to the test cell. The method for determining differentiation of a cell is capable of detecting the presence or absence of an undifferentiated stem cell in test cells by using a probe that specifically reacts with undifferentiated stem cells and detecting the presence of bonding to the test cell. (A) A protein comprising an amino acid sequence shown in SEQ ID NO: 1 and recognizing a sugar chain structure of "Fuc±1-2Gal²1-3GlcNAc" and/or "Fuc±1-2Gal²1-3GalNAc;" and (B) a protein comprising an amino acid sequence showing 80% or more similarity to the amino acid sequence shown in SEQ ID NO: 1 and recognizing a sugar chain structure of "Fuc±1-2Gal²1-3GlcNAc" and/or "Fuc±1-2Gal²1-3GalNAc."

公开(公告)号：EP2913874A4

公开(公告)日：2015-10-28

申请号：EP13848519

申请日：2013-10-25

申请人： WAKO PURE CHEM IND LTD ,  UNIV TOKYO SCIENCE FOUNDATION

发明人： KOMABA SHINICHI ,  YABUUCHI NAOAKI ,  HAN ZHEN-JI ,  SASAKI TAKEO ,  HASHIMOTO SHOTA ,  OKAMOTO KUNIAKI ,  MAESAWA TSUNEAKI

IPC分类号： H01M4/62 ,  C08F220/06 ,  C08G18/02 ,  C08G59/40 ,  C08K5/00 ,  C08K5/29 ,  C08L33/02 ,  C08L63/00 ,  C08L79/00 ,  H01M4/134 ,  H01M4/36 ,  H01M4/38 ,  H01M10/052

CPC分类号： H01M4/622 ,  C08F122/02 ,  C08G18/025 ,  C08G59/40 ,  C08K5/0025 ,  C08L33/02 ,  C08L63/00 ,  C08L79/00 ,  H01M4/134 ,  H01M4/386 ,  H01M4/625 ,  H01M10/052 ,  H01M10/0525 ,  H01M2004/027 ,  H01M2220/20 ,  C08F220/06 ,  C08F222/1006

摘要： It is an object of the present invention to provide an electrode capable of maintaining superior capacity retention without destruction of an electrode structure, even in the case of using an active material including silicon. The present invention relates to "a binder for a lithium cell, the binder comprising polyacrylic acid cross-liked by a cross-linking agent selected from the compounds described in the general formulae [1] to [13] and the polymer described in the general formula [14] (provided that the one which includes a functional group-containing vinylidene fluoride-based polymer is excluded)"; a "composition for producing an electrode of a lithium cell, the composition comprising 1) an active material containing silicon, 2) a conductive assistant and 3) a cross-linked-type polyacrylic acid (provided that the one containing a functional group-containing vinylidene fluoride-based polymer is excluded)"; and an "electrode for a lithium cell, the electrode comprising 1) an active material containing silicon, 2) a conductive assistant, 3) a cross-linked-type polyacrylic acid, and 4) a current collector (provided that the one containing a functional group-containing vinylidene fluoride-based polymer is excluded)".

公开(公告)号：EP2774994A4

公开(公告)日：2015-09-02

申请号：EP12845274

申请日：2012-10-31

申请人： NAT INST OF ADVANCED IND SCIEN ,  WAKO PURE CHEM IND LTD

发明人： TATENO HIROAKI ,  HIRABAYASHI JUN ,  ITO YUZURU ,  ONUMA YASUKO ,  ASASHIMA MAKOTO ,  KUNO ATSUSHI ,  WARASHINA MASAKI ,  FUKUDA MASAKAZU

IPC分类号： C12Q1/04 ,  C07K14/47 ,  C12N5/0735 ,  C12N5/10 ,  C12N15/09 ,  G01N33/53

CPC分类号： G01N33/56966 ,  C07K14/195 ,  G01N2333/4724 ,  G01N2400/00

公开(公告)号：EP2803672A4

公开(公告)日：2015-08-19

申请号：EP13736389

申请日：2013-01-07

申请人： WAKO PURE CHEM IND LTD

发明人： KOZAKI ATSUSHI ,  SATO MICHIHIKO

IPC分类号： C07J9/00 ,  C08G73/10 ,  C09D179/08 ,  G02F1/1337

CPC分类号： C09K19/56 ,  C07J9/00 ,  C07J41/0055 ,  C07J71/0005 ,  C08G73/10 ,  C08G73/1042 ,  C08G73/1075 ,  C08G73/1078 ,  C09D179/08 ,  G02F1/133723 ,  H05K3/287

公开(公告)号：EP2474527A4

公开(公告)日：2014-06-11

申请号：EP10812034

申请日：2010-08-30

申请人： WAKO PURE CHEM IND LTD

发明人： WATAHIKI TSUTOMU ,  OKAMOTO KUNIAKI ,  SUMINO MOTOSHIGE

IPC分类号： C07C309/20 ,  C07D213/06 ,  C07D213/20 ,  C07D213/68 ,  C07D233/58 ,  C07D295/04 ,  C07D295/08

CPC分类号： C07C309/20 ,  C07D213/06 ,  C07D213/20 ,  C07D213/68 ,  C07D233/58 ,  C07D295/04 ,  C07D295/08