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公开(公告)号:EP3704090A1
公开(公告)日:2020-09-09
申请号:EP18812425.9
申请日:2018-11-02
发明人: MARTIN, Kathleen, Ann , SIDRAUSKI, Carmela , FROST, Jennifer, M. , TONG, Yunsong , XU, Xiangdong , CHUNG, Seungwon , ZHANG, Qingwei, I. , SHI, Lei , MURAUSKI, Kathleen , DART, Michael, J. , RANDOLPH, John, T.
IPC分类号: C07C233/00 , C07C235/00 , C07C237/00 , A61P19/00 , A61P25/00 , A61P21/00 , A61P35/00 , A61K31/16 , A61K31/165 , A61K31/538 , A61K31/352 , A61K31/36 , A61K31/498 , C07D311/66 , C07D319/20 , C07D405/12 , C07D413/06 , C07D265/36 , C07D493/04 , C07D207/22 , C07D209/42
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公开(公告)号:EP3710428A1
公开(公告)日:2020-09-23
申请号:EP18811984.6
申请日:2018-11-02
发明人: MARTIN, Kathleen, Ann , SIDRAUSKI, Carmela , FROST, Jennifer, M. , PLIUSHCHEV, Marina, A. , TONG, Yunsong , BLACK, Lawrence, A. , XU, Xiangdong , SHI, Lei , ZHANG, Qingwei, I. , CHUNG, Seungwon , SWEIS, Ramzi, Farah , DART, Michael, J. , RANDOLPH, John, T. , MURAUSKI, Kathleen
IPC分类号: C07D213/74 , C07C255/57 , C07D231/14 , C07D237/10 , C07D241/12 , C07D241/44 , C07D261/08 , C07D235/14 , C07D307/56 , C07D307/82 , C07D317/62 , C07D401/04 , C07D413/04 , C07D487/04 , C07D275/03 , C07D495/04 , C07D513/04 , C07D213/54 , A61P35/00 , A61K31/165
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公开(公告)号:EP3452456A1
公开(公告)日:2019-03-13
申请号:EP17723904.3
申请日:2017-05-05
发明人: SIDRAUSKI, Carmela , PLIUSCHEV, Marina , FROST, Jennifer, M. , BLACK, Lawrence, A. , XU, Xiangdong , SWEIS, Ramzi, Farah , SHI, Lei , ZHANG, Qinwei, I. , TONG, Yunsong , HUTCHINS, Charles, W. , CHUNG, Seungwon , DART, Michael, J.
IPC分类号: C07D241/12 , C07D261/08 , C07D213/57 , C07C233/74 , C07D213/74 , C07D231/14 , C07D237/10 , C07D241/44 , C07D277/32 , C07D213/54 , C07D307/56 , C07D307/82
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公开(公告)号:EP2376462B1
公开(公告)日:2015-12-16
申请号:EP09775056.6
申请日:2009-12-16
申请人: AbbVie Inc.
发明人: FROST, Jennifer, M. , LATSHAW, Steven, P. , DART, Michael, J. , CARROLL, William, A. , PEREZ-MEDRANO, Arturo , KOLASA, Teodozyj , PATEL, Meena , NELSON, Derek, W. , LI, Tongmei , PEDDI, Sridhar , WANG, Xueqing , LIU, Bo
IPC分类号: C07D277/46 , C07D417/12 , C07D513/04 , A61K31/426 , A61K31/427 , A61K31/428 , A61P3/04 , A61P3/10 , A61P9/00 , A61P11/00 , A61P29/00 , A61P35/00
CPC分类号: C07D417/12 , C07D277/46 , C07D513/04
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公开(公告)号:EP2411371B1
公开(公告)日:2015-05-20
申请号:EP10724168.9
申请日:2010-03-26
申请人: AbbVie Inc.
发明人: WANG, Xueqing , DART, Michael, J. , LIU, Bo
IPC分类号: C07D231/40 , C07D285/135 , A61K31/433 , A61P25/04
CPC分类号: C07D231/40 , C07D285/135
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公开(公告)号:EP4356971A3
公开(公告)日:2024-07-24
申请号:EP23213609.3
申请日:2017-05-05
发明人: SIDRAUSKI, Carmela , PLIUSHCHEV, Marina , FROST, Jennifer, M. , BLACK, Lawrence, A. , XU, Xiangdong , SWEIS, Ramzi, Farath , SHI, Lei , ZHANG, Qingwei , TONG, Yunsong , HUTCHINS, Charles, W. , CHUNG, Seungwon , DART, Michael, J.
IPC分类号: C07D213/73 , C07D317/64 , C07D231/56 , C07D401/04 , C07D237/14 , C07D237/16 , C07D405/08 , C07D241/18 , C07D471/04 , C07D261/08 , C07D261/20 , C07C235/00 , C07D271/113 , C07D213/30 , C07D213/64 , C07D213/66 , A61K31/44 , A61P35/00
CPC分类号: C07D213/73 , C07D317/64 , C07D231/56 , C07C311/13 , C07D401/04 , C07C311/24 , C07D237/14 , C07D237/16 , C07C317/22 , C07D405/08 , C07D241/18 , C07D261/08 , C07D261/20 , C07C235/22 , C07D271/113 , C07D213/30 , C07D213/64 , C07D213/66 , C07C2602/3820170501 , C07C2602/4020170501 , C07C2602/4220170501 , C07C2602/4420170501 , C07C2603/9020170501 , C07D471/04 , A61P25/28
摘要: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
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公开(公告)号:EP4237413A1
公开(公告)日:2023-09-06
申请号:EP21830358.4
申请日:2021-10-29
发明人: MARTIN, Kathleen, Ann , SIDRAUSKI, Carmela , DART, Michael, J. , MURAUSKI, Kathleen, J. , RANDOLPH, John, T. , SHI, Lei , SMITH, Russell, C. , TONG, Yunsong , XU, Xiangdong , BENELKEBIR, Hanae , CHOHAN, Kamaldeep, K. , EDESON, Steven, J. , SCHWENK, Sebastian , STARBUCK, Kathryn, A.
IPC分类号: C07D231/12 , C07D231/18 , C07D231/20 , C07D231/56 , C07D311/24 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D471/04 , C07D213/64 , C07D249/04 , C07D401/04 , C07D401/06 , C07D403/04
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公开(公告)号:EP3962906A1
公开(公告)日:2022-03-09
申请号:EP20727069.5
申请日:2020-04-30
发明人: MARTIN, Kathleen, Ann , SIDRAUSKI, Carmela , SHI, Lei , MURAUSKI, Kathleen, J. , XU, Xiangdong , TONG, Yunsong , RANDOLPH, John, T. , DART, Michael, J. , BENELKEBIR, Hanae , EDESON, Steven , STARBUCK, Kathryn
IPC分类号: C07D311/74 , A61P25/00 , A61P35/00 , A61P37/00 , C07C1/00 , C07D213/53 , C07D265/36 , C07D271/10 , C07D405/06 , C07D405/12 , C07D405/14 , C07D407/12 , C07D413/04 , C07D413/12 , C07D417/12
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公开(公告)号:EP3864003A1
公开(公告)日:2021-08-18
申请号:EP19795413.4
申请日:2019-10-11
发明人: MARTIN, Kathleen, Ann , SIDRAUSKI, Carmela , DART, Michael, J. , FROST, Jennifer, M. , TONG, Yunsong , XU, Xiangdong , SHI, Lei , MURAUSKI, Kathleen , PLIUSHCHEV, Marina , BROWN, Brian, S. , VOIGHT, Eric , RANDOLPH, John, T.
IPC分类号: C07C235/36 , C07C271/34 , C07C303/34 , C07D221/00 , C07F9/09
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公开(公告)号:EP3452448A1
公开(公告)日:2019-03-13
申请号:EP17723899.5
申请日:2017-05-05
发明人: SIDRAUSKI, Carmela , PLIUSHCHEV, Marina , FROST, Jennifer, M. , BLACK, Lawrence, A. , XU, Xiangdong , SWEIS, Ramzi, Farath , SHI, Lei , ZHANG, Qinwei, I. , TONG, Yunsong , HUTCHINS, Charles, W. , CHUNG, Seungwon , DART, Michael, J.
IPC分类号: C07D213/73 , C07D317/64 , C07D231/56 , C07D401/04 , C07D237/14 , C07D237/16 , C07D405/08 , C07D241/18 , C07D471/04 , C07D261/08 , C07D261/20 , C07C235/00 , C07D271/113 , C07D213/30 , C07D213/64 , C07D213/66 , A61K31/44 , A61P35/00
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