DROPLET ACTUATOR STRUCTURES
    7.
    发明公开
    DROPLET ACTUATOR STRUCTURES 有权
    液滴驱动器结构

    公开(公告)号:EP2121329A1

    公开(公告)日:2009-11-25

    申请号:EP08731243.5

    申请日:2008-03-03

    IPC分类号: B41J2/045

    摘要: Approaches to configuring and wiring electrodes in a droplet actuator are provided. Droplet actuators employing the designs of the invention are useful for conducting a variety of droplet operations. In one set of embodiments, the droplet actuator of the invention includes various single-layer wiring configurations for mitigating the constraints and drawbacks that are associated with single-layer designs, such as wireability constraints, limited mechanisms for performing droplet operations, electrostatic interference from wires, and any combinations thereof. In another set of embodiments, the droplet actuator of the invention includes a reference electrode that is situated on one substrate that is separated by a gap from a second substrate and one or more control electrodes that are situated on the second substrate. The control electrodes may be placed such that the second substrate is interposed between the control electrodes and the first substrate.

    摘要翻译: 提供了在液滴致动器中配置和布线电极的方法。 采用本发明设计的液滴致动器可用于进行各种液滴操作。 在一组实施例中,本发明的液滴致动器包括用于缓解与单层设计相关的约束和缺陷的各种单层布线配置,例如可接线性约束,用于执行液滴操作的有限机制,来自导线的静电干扰 ,及其任何组合。 在另一组实施例中,本发明的液滴致动器包括参考电极,该参考电极位于与第二衬底间隔开的一个衬底上,以及位于第二衬底上的一个或多个控制电极。 控制电极可以被放置为使得第二基板插入在控制电极和第一基板之间。

    ANALYSIS OF DNA
    8.
    发明公开
    ANALYSIS OF DNA 审中-公开
    DNA - 分析

    公开(公告)号:EP2992083A1

    公开(公告)日:2016-03-09

    申请号:EP14791467.5

    申请日:2014-05-01

    IPC分类号: C12M1/34

    摘要: The invention provides pyrosequencing-based methods of analyzing and synthesizing DNA, including methods of DNA error correction, determining DNA size distribution, screening for nucleotide repeat disorders such as fragile X syndrome, determining size distribution and bias in a DNA library, and determining pyrosequencing read length. The methods include on-bench protocols as well as droplet-based protocols that may be conducted on a droplet actuator.

    摘要翻译: 本发明提供了基于焦磷酸测序的分析和合成DNA的方法,包括DNA错误校正的方法,确定DNA大小分布,筛选核苷酸重复病症如脆性X综合征,确定DNA文库中的大小分布和偏差,以及确定焦磷酸测序读数 长度。 这些方法包括工作台协议以及可以在液滴致动器上进行的基于液滴的协议。