公开(公告)号：EP1793906B1

公开(公告)日：2015-01-28

申请号：EP05778415.9

申请日：2005-08-05

申请人： Akers Biosciences, Inc.

发明人： RUSSELL, Donald ,  MILUNIC, David

IPC分类号： B01D29/00 ,  B01D29/01 ,  B01D35/00 ,  B01D37/00 ,  B01D39/06 ,  B01D39/20 ,  D21H13/40 ,  G01N33/49

CPC分类号： B01D39/2017 ,  D21H13/40 ,  G01N33/491 ,  Y10T156/109 ,  Y10T442/2008

公开(公告)号：EP1810031A2

公开(公告)日：2007-07-25

申请号：EP05810321.9

申请日：2005-10-04

申请人： Akers Biosciences, Inc.

发明人： MILUNIC, David ,  ANDRELCZYK, Susan

IPC分类号： G01N33/543

CPC分类号： G01N33/6863 ,  B01L3/5023 ,  B01L2200/16 ,  B01L2300/0681 ,  B01L2400/0683 ,  G01N33/54313 ,  G01N33/564 ,  G01N33/6893 ,  G01N33/86 ,  G01N2333/522 ,  G01N2400/40 ,  G01N2800/222

摘要： Methods for determining the presence of heparin/platelet factor 4 antibodies in a sample suspected to contain heparin/platelet factor 4 antibodies are provided, along with apparatus suitable for performing the methods. The method depends upon a color visualization indicating the presence or absence of heparin/platelet factor 4 antibodies in the sample. Preferred methods comprise contacting the sample with particles being complexed to platelet factor 4 (PF4) and which particle-complexed PF4 reacts specifically with heparin/platelet factor 4 antibodies, passing the sample/particle mixture through a filter, and then analyzing the color of the filtrate. The presence of heparin/platelet factor 4 antibodies in the sample is established where the color of the filtrate is substantially different from the color of the receptor-bearing particles.

公开(公告)号：EP1793906A1

公开(公告)日：2007-06-13

申请号：EP05778415.9

申请日：2005-08-05

申请人： Akers Biosciences, Inc.

发明人： RUSSELL, Donald ,  MILUNIC, David

IPC分类号： B01D29/00 ,  B01D29/01 ,  B01D35/00 ,  B01D37/00 ,  B01D39/06

CPC分类号： B01D39/2017 ,  D21H13/40 ,  G01N33/491 ,  Y10T156/109 ,  Y10T442/2008

摘要： A novel composite of glass fiber paper and reinforcing material that is useful for high speed manufacturing of devices comprising it is disclosed. The composite is formed by pressing into a glass fiber paper, having multimodal (at least bi-modal) composition, a hydrophilic reinforcing material. The composite has anisotropic separation properties that are particularly useful for preparing a fluid fraction from whole blood. The preferred glass fiber paper comprises glass fibers such that there are a plurality of short fibers (6) having large diameters and long fibers (2) with smaller diameters. The preferred glass fiber paper also exhibits partial ordering. There are many more of the long fibers (2) with smaller diameters than of the short fibers (6) having large diameters. Also disclosed are several blood separator device designs for efficiently separating the fluid fraction of blood from whole blood using the composite.