摘要:
An object of the present invention is to provide a probe, primer, primer set and antibody for determining neonatal alloimmune thrombocytopenic purpura or the risk of developing it. According to the present invention, there is provided a probe, primer, primer set and antibody for use in the detection of the thymine residue at position 1297 in the GPIIIa.
摘要:
Compositions and methods are provided for determining platelet reactivity where the levels of FcγRIIa on the surface of platelets is measured and if the levels of FcγRIIa are greater than a reference value, the platelets have enhanced reactivity.
摘要:
A blood analyzer is provided that comprises: a measurement unit that measures a blood sample and output measurement data; a controller that analyzes the measurement data outputted from the measurement unit, generates analysis data on each of blood cell types including red blood cell, white blood cell, and platelet, and generates support information for discriminating a cause of a reduction in the number of blood cells of a predetermined type among the blood cell types from analysis data including first analysis data on the predetermined blood cell type and second analysis data on a blood cell type other than the predetermined blood cell type; and an output unit that outputs the support information.
摘要:
A method for diagnosis of HIT (Heparin-induced thrombocytopenia) in a patient's serum or plasma sample and a system comprising kits for performing the method are provided, where the method involves incubating a patient's sample with and without heparin and normal control sample with and without heparin with a platelet-rich plasma (PRP) of an individual not having a platelet disorder and then incubating an aliquot of each sample with a first label for both heparin activated and non-heparin activated platelets and a second label for platelets activated by the heparin-immune complex formed in the patient sample. HIT is diagnosed when the difference between the amount of activated platelets from the patient's sample with and without heparin is substantially larger than the difference between the normal control sample with and without heparin.
摘要:
A microchip for measuring platelet function by allowing blood to flow through a channel to induce platelet aggregation, wherein the microchip comprises a channel provided inside thereof, wherein at least a part of the channel is coated with collagen for allowing adhesion of platelets; a plurality of walls extend along the direction of the flow of blood in the channel and divide the width of the channel to form a channel dividing section; and the walls are treated to have a surface roughness (Ra) of 10 to 200 nm.