摘要:
A non-contact apparatus for acquiring velocity information off of an internal rotating housing of an Adams-type centrifuge (10). The apparatus includes a bidirectional transmitter of radiant energy, such as a fiber-optical member (52), positioned at the axis of rotation of the exterior rotatable housing of the centrifuge. A ring (58) of reflective, spaced-apart, members is formed on the lower surface of the rotatable housing adjacent the end of the fiber-optic member. Radiant energy from an exterior, fixed, light source (42) is transmitted through the fiber-optic member and is incident upon the rotating ring. Radiant energy reflected off of the reflecting members of the ring passes back through the fiber-optic member and can be sensed in an externally located, stationary optical sensor (66). The optical sensor generates a train of electrical pulses in response to the incident pulses of reflected radiant energy.
摘要:
A disposable prepackaged fluid processing module (20) for deriving plasma from whole blood includes an integral housing (22) wherein anticoagulant (ACD), saline and collection containers (43,44, and 30), tubing segments (27,28,31,56,60), a membrane filter element (141), and other components (63) required in the procedure are contained. Fluid communication between the containers, tubing segments and filter element is provided by a fluid circuit formed by a panel (36) of the housing (22), and an overlying fluid-impermeable flexible sheet member (71). The fluid circuit includes pump and valve elements (130-137) which operate in response to pressures applied to the sheet member. Upon installation of the system in a related actuator apparatus (21), pneumatic actuator ports (100-107) apply pressures to the pump and valve elements to circulate fluid through the fluid circuit.
摘要:
A blood component collection system (10, 12) which comprises first means (14) for collecting whole blood from a donor for separation into essentially red blood cells and platelet-rich plasma. The system (10, 12) also includes second means (16) for receiving the platelet-rich plasma from the first means (14) and for noncentrifugally separating the platelet-rich plasma into platelet concentrate and virtually platelet-free plasma. The blood component collection system (10, 12) which embodies the first means (14) and second means (16) of the invention is applicable for use in the context of either a nonautomated batch centrifugation process (10) or a continuous flow procedure (12).
摘要:
An apparatus and method of separating a component from a collected quantity of fluid. The apparatus (10) includes a dual member centrifuge (12) and an associated fluid flow transfer set (14). The transfer set (14) has a collection container (44) in which a quantity of fluid can be initially accumulated. The collection container (44) is formed as a disk-shaped plastic member with an elongated generally radially extending barrier member formed therein. A component collection container (64) is in fluid flow communication with the disk-shaped container. The method provides for centrifugation of the collection container (44) in the dual member centrifuge (12) thereby separating out the selected fluid component. The component can then be pumped out of the collection container (44) into the component accumulation container (64). The residual fluid can be sealed in the collection container for later use. The component collection container can be separated and sealed also for later use.
摘要:
The apparatus comprises an elongate, flexible separation chamber (51) receivable in a slot (46) of a rotor, so that rotation of the rotor causes separation of a fluid, supplied through an inlet port (51a) to the chamber (51), in regions (104,106) along opposite walls (50d,50e) of the chamber. Each component is removed through a corresponding outlet port (51b,51c). One of the outlet ports (51c) is arranged adjacent to the inlet port (51a) and a ramp (111) is provided or formed in the chamber (51) to direct flow of the respective component towards that outlet in a direction opposite to the direction of fluid flow through the inlet.
摘要:
A blood separation system operates in a first mode to convey whole blood into the inlet region (48) of a blood processing chamber (38) for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber (38), while maintaining the interface within the chamber (38). The system operates in a second mode to remove the interface from the chamber (38) by conveying packed red blood cells into the inlet region (48). An outlet path (46) conveys the removed interface from the chamber (38). The outlet path (46) includes a first sensing element (OS) to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.
摘要:
A blood separation system operates in a first mode to convey whole blood into the inlet region (48) of a blood processing chamber (38) for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber (38), while maintaining the interface within the chamber (38). The system operates in a second mode to remove the interface from the chamber (38) by conveying packed red blood cells into the inlet region (48). An outlet path (46) conveys the removed interface from the chamber (38). The outlet path (46) includes a first sensing element (OS) to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.
摘要:
The apparatus comprises an elongate, flexible separation chamber (51) receivable in a slot (46) of a rotor, so that rotation of the rotor causes separation of a fluid, supplied through an inlet port (51a) to the chamber (51), in regions (104,106) along opposite walls (50d,50e) of the chamber. Each component is removed through a corresponding outlet port (51b,51c). One of the outlet ports (51c) is arranged adjacent to the inlet port (51a) and a ramp (111) is provided or formed in the chamber (51) to direct flow of the respective component towards that outlet in a direction opposite to the direction of fluid flow through the inlet.
摘要:
Appareil et procédé de séparation d'un composant à partir d'une quantité de fluide collecté. L'appareil (10) comprend une centrifugeuse (12) à deux éléments et un appareillage associé (14) de transfert de l'écoulement de fluide. L'appareillage de transfert (14) possède un conteneur de récupération (44) dans lequel une quantité de fluide peut être initialement accumulée. Le conteneur de récupération (44) est configuré comme un disque en plastique ayant à l'intérieur une barrière s'étendant radialement et généralement allongée. Un conteneur de récupération (64) du composant est en communication d'écoulement fluide avec le conteneur en forme de disque. Le procédé consiste à effectuer une centrifugation dans le conteneur de récupération (44) avec la centrifugeuse (12) à double élément de manière à isoler le composant fluide sélectionné. Le composant peut ensuite être extrait du conteneur de récupération (44) par pompage et être amené dans le conteneur (64) d'accumulation du composant. Le fluide résiduel peut être stocké hermétiquement dans le conteneur de récupération pour une utilisation ultérieure. Le conteneur de récupération du composant peut être séparé et fermé hermétiquement également à des fins d'utilisation ultérieure.