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1.发明公开
公开(公告)号：EP1042305A4
公开(公告)日：2003-05-14
申请号：EP98964221
申请日：1998-12-22
申请人： BAYER AG
发明人： MILLER SCOTT , OSTERHOUT MARTIN , DUMAS JACQUES , KHIRE UDAY , LOWINGER TIMOTHY BRUNO , RIEDL BERND , SCOTT WILLIAM J , SMITH ROGER A , WOOD JILL E , GUNN DAVID , HATOUM-MOKDAD HOLIA , RODRIGUEZ MARELI , SIBLEY ROBERT , WANG MING , TURNER TIFFANY , BRENNAN CATHERINE
IPC分类号： C07D295/18 , A61K31/17 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/4015 , A61K31/4025 , A61K31/403 , A61K31/4035 , A61K31/4166 , A61K31/425 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/535 , A61K31/5375 , A61P29/00 , A61P43/00 , C07C205/11 , C07C205/22 , C07C205/37 , C07C205/38 , C07C205/57 , C07C205/58 , C07C275/30 , C07C275/32 , C07C275/34 , C07C275/36 , C07C275/40 , C07C275/42 , C07C309/88 , C07C311/48 , C07C317/42 , C07C323/44 , C07C335/18 , C07D207/26 , C07D207/27 , C07D207/40 , C07D207/404 , C07D209/76 , C07D209/86 , C07D209/88 , C07D213/36 , C07D213/40 , C07D213/53 , C07D213/68 , C07D213/70 , C07D231/08 , C07D233/22 , C07D233/34 , C07D233/70 , C07D263/58 , C07D273/00 , C07D275/00 , C07D277/68 , C07D295/185 , C07D307/20 , C07D333/20 , C07D409/12
CPC分类号： C07D207/27 , A61K31/17 , A61K31/40 , A61K31/403 , A61K31/4035 , A61K31/425 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4436 , A61K31/4439 , A61K31/535 , A61K31/5375 , C07C205/11 , C07C205/22 , C07C205/37 , C07C205/38 , C07C205/57 , C07C205/58 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07C275/42 , C07C309/88 , C07C311/48 , C07C317/42 , C07D207/26 , C07D207/404 , C07D209/76 , C07D209/86 , C07D209/88 , C07D213/40 , C07D213/53 , C07D213/68 , C07D213/70 , C07D231/08 , C07D233/22 , C07D233/70 , C07D263/58 , C07D277/68 , C07D295/185 , C07D307/20 , C07D333/20 , C07D409/12
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
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2.发明公开INHIBITION OF RAF KINASE USING SYMMETRICAL AND UNSYMMETRICAL SUBSTITUTED DIPHENYL UREAS 有权RAF激酶的抑制使用平衡和不平衡取代脲
公开(公告)号：EP1049664A4
公开(公告)日：2001-05-16
申请号：EP98963809
申请日：1998-12-22
申请人： BAYER AG
发明人： MILLER SCOTT , OSTERHOUT MARTIN , DUMAS JACQUES , KHIRE UDAY , LOWINGER TIMOTHY BRUNO , RIEDL BERND , SCOTT WILLIAM J , SMITH ROGER A , WOOD JILL E , GUNN DAVID , RODRIGUEZ MARELI , WANG MING
IPC分类号： C07C275/28 , A61K31/17 , A61K31/357 , A61K31/36 , A61K31/38 , A61K31/381 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K31/4427 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/47 , A61K31/505 , A61P35/00 , A61P43/00 , C07C275/24 , C07C275/30 , C07C275/32 , C07C275/36 , C07C275/38 , C07C275/40 , C07C323/44 , C07D209/00 , C07D213/00 , C07D213/02 , C07D213/04 , C07D213/32 , C07D213/40 , C07D213/50 , C07D213/60 , C07D213/65 , C07D213/68 , C07D213/69 , C07D213/70 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/89 , C07D215/20 , C07D239/24 , C07D239/38 , C07D241/12 , C07D277/32 , C07D277/68 , C07D307/20 , C07D317/48 , C07D317/64 , C07D319/08 , C07D333/02 , C07D401/04 , C07D401/12 , C07D409/12 , C07C275/42 , C07D213/36 , C07D333/20
CPC分类号： C07D213/40 , C07C275/36 , C07D213/32 , C07D213/50 , C07D213/65 , C07D213/68 , C07D213/69 , C07D213/70 , C07D213/75 , C07D213/81 , C07D213/89 , C07D215/20 , C07D239/38 , C07D277/68 , C07D317/64 , C07D401/04 , C07D401/12 , C07D409/12
摘要： This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
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