专利检索 ap:("Bayer AG" OR "Bayer Pharma Aktiengesellschaft" OR "The Broad Institute, Inc." OR "President AND Fellows of Harvard College" OR "The General Hospital Corporation") AND inv:"JANZER, Andreas" 第 1 页

1.

发明公开
4,5-ANNULATED 1,2,4-TRIAZOLONES 审中-公开

公开(公告)号：EP3532474A2

公开(公告)日：2019-09-04

申请号：EP17797091.0

申请日：2017-10-25

申请人： Bayer AG , Bayer Pharma Aktiengesellschaft , The Broad Institute, Inc. , President and Fellows of Harvard College , The General Hospital Corporation

发明人： GRADL, Stefan, Nikolaus , NGUYEN, Duy , EIS, Knut , GUENTHER, Judith , STELLFELD, Timo , JANZER, Andreas , CHRISTIAN, Sven , MUELLER, Thomas , EL SHEIKH, Sherif , ZHOU, Han, Jie , ZHAO, Changjia , SYKES, David B , FERRARA, Steven, James , LIU, Kery , HERBERT, Simon, Anthony , MERZ, Claudia , NIEHUES, Michael , NISING, Carl, Friedrich , SCHÄFER, Martina , ZIMMERMANN, Katja , KNAEBLEIN, Jörg , THEDE, Kai , FAUPEL, Thomas

IPC分类号： C07D471/04 , A61K31/4196 , C07D487/04 , C07D498/04 , C07D513/04 , C12N15/70

2.

发明公开
COMPOUNDS AND METHODS USEFUL FOR TREATING OR PREVENTING HEMATOLOGICAL CANCERS 审中-公开

公开(公告)号：EP3344243A1

公开(公告)日：2018-07-11

申请号：EP16762989.8

申请日：2016-08-29

申请人： The Broad Institute Inc. , The General Hospital Corporation , BAYER PHARMA AKTIENGESELLSCHAFT , President and Fellows of Harvard College

发明人： SYKES, David B. , SCADDEN, David , LEWIS, Timothy A. , JANZER, Andreas , MEYER, Hanna , STÖCKIGT, Detlef

IPC分类号： A61K31/27 , A61K31/42 , A61K31/505 , A61P35/02

CPC分类号： A61K31/47 , A61K31/27 , A61K31/277 , A61K31/42 , A61K31/505 , A61K33/36 , A61P35/02

摘要： The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with DHODH inhibitors, such as 6-fluoro-2-(2′-fluoro-[1,1′-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid).

3.

发明公开
2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH 审中-公开

公开(公告)号：EP3532468A1

公开(公告)日：2019-09-04

申请号：EP17788234.7

申请日：2017-10-25

申请人： Bayer Aktiengesellschaft , Bayer Pharma Aktiengesellschaft , The Broad Institute Inc. , President and Fellows of Harvard College , The General Hospital Corporation

发明人： GRADL, Stefan, Nikolaus , NGUYEN, Duy , EIS, Knut , GÜNTHER, Judith , STELLFELD, Timo , JANZER, Andreas , CHRISTIAN, Sven , MUELLER, Thomas , EL SHEIKH, Sherif El , ZHOU, Han, Jie , ZHAO, Changjia , SYKES, David Brian , FERRARA, Steven, James , LIU, Kery , KRÖBER, Michael , MERZ, Claudia , NIEHUES, Michael , SCHÄFER, Martina , ZIMMERMANN, Katja , NISING, Carl, Friedrich

IPC分类号： C07D403/12 , C07D401/12 , C07D405/12 , C07D413/12 , C07D249/12 , A61K31/4196 , A61P35/02

4.

发明公开
THIAZOLE COMPOUNDS USEFUL AS PRMT5 INHIBITORS 审中-公开

公开(公告)号：EP3645531A1

公开(公告)日：2020-05-06

申请号：EP18731125.3

申请日：2018-06-21

申请人： Bayer Aktiengesellschaft , Bayer Pharma Aktiengesellschaft

发明人： BOUCHÉ, Léa, Aurélie , NGUYEN, Duy , KORR, Daniel , KOPPITZ, Marcus , TER LAAK, Antonius , FERNANDEZ-MONTALVAN, Amaury, Ernesto , NGUYEN, Thi, Thanh, Uyen , PRECHTL, Stefan , JANZER, Andreas

IPC分类号： C07D417/12 , C07D417/14 , C07D277/56 , A61P35/00 , A61K31/427